Effect of constant administration of a gonadotropin-releasing hormone agonist on reproductive activity in mares: induction of ovulation during seasonal anestrus

The potential of a gonadotropin-releasing hormone (GnRH) agonist (goserelin acetate), delivered constantly for 28 days via a subcutaneous depot, to induce ovulation in seasonally anestrous mares, was investigated. Two experiments were conducted, in which a range of doses (30 to 240 micrograms/mare/d) was examined. Mares were selected on the basis of lack of substantial follicular development (follicle diameter < 20 mm determined ultrasonically) and low serum concentrations of luteinizing hormone (LH) and progesterone. Constant administration of the GnRH agonist-induced ovulation in anestrous mares, but a dose-response relation was not observed. Furthermore, with identical doses tested in consecutive or alternate years, considerable variation was observed in the ovulatory response. In general, ovulation in all treated mares was accompanied by increased circulating concentrations of LH and a decrease in follicle-stimulating hormone values. Ovulation was preceded by an increase in estradiol and LH concentrations. In mares in which ovulation did not occur, concentration of LH increased during agonist treatment, whereas that of follicle-stimulating hormone either increased or did not change. It was concluded that constant administration of GnRH agonists may induce ovulation in mares during seasonal anestrus; however, percentage of mares ovulating and the lack of reproducibility of effect indicate that this approach is inappropriate for use as a reliable method to manipulate breeding activity in commercial broodmares.     

A Daily Diary Validity Test of Drinking to Cope Measures.

Data from 2 daily diary studies of stress, negative affect, and drinking were used to examine the correspondence between global self-reports of drinking to cope (DTC) and within-person stress/negative affect-drinking associations. In Study 1, 83 community-residing drinkers recorded data in nightly booklets on negative events, perceived stress, negative affect, and drinking for 60 consecutive days. In Study 2, 88 community-residing drinkers recorded data on negative events and negative interpersonal exchanges nightly and negative affect and drinking in near-real time on palmtop computers for 30 consecutive days. Both studies showed only modest correspondence between self-reported DTC and between-person differences in within-day, daily, and weekly associations between stress/negative affect and drinking. The findings indicate that individuals who report higher DTC simply may drink across a wider variety of conditions than those who report relatively lower DTC. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Rigor, rigor mortis, and conspiratorial views of depression research.

The authors reassert the need for methodological changes in depression research appearing in the Journal of Personality and Social Psychology and other personality and social psychology journals. In this rejoinder the authors update their earlier literature review (H. Tennen, J. Hall, & G. Affleck; see record 1995-31710-001) and respond to the commentaries by P C. Kendall and E. C. Flannery-Schroeder (see record 1995-31700-001) and G. Weary, J. A. Edwards, and J. A. Jacobson (see record 1995-31713-001). The authors notice that G. Weary et al.'s own findings demonstrate the need to change how depression is measured and participants are assigned to experimental groups. The authors also challenge G. Weary et al.'s contention that structured interviews are limited because they require interviewer judgments, and they urge personality and social psychologists to learn more about these interviews. Finally, G. Weary et al.'s suspicion that depression research guidelines reflect professional parochialism is disputed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Depression history and coping with chronic pain: A daily process analysis.

This study examined how a previous episode of depression is related to daily pain and reactions to pain among individuals with fibromyalgia, a chronic pain syndrome. Seventy-one women with fibromyalgia (including 30 who were previously depressed) rated their pain and mood 3 times daily for 30 days. Each night, participants rated the extent to which they responded to pain by catastrophizing, how much control they had over that day's pain, their ways of coping with pain that day, and the effectiveness of their coping efforts. Multivariate multilevel regression models revealed that after controlling for neuroticism and current depressive symptoms, formerly depressed and never-depressed individuals differed in how they coped with increased pain and in how they appraised the efficacy of their coping efforts. Formerly depressed participants who also reported more current depressive symptoms showed a greater decline in pleasant mood on more painful days than did formerly depressed participants who were experiencing fewer current depressive symptoms. These findings illustrate how a history of depression can be captured in the dynamics of daily life. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Paper and plastic in daily diary research: Comment on Green, Rafaeli, Bolger, Shrout, and Reis (2006).

The authors applaud A. S. Green, E. Rafaeli, N. Bolger, P. E. Shrout, and H. T. Reis's (2006) response to one-sided comparisons of paper versus electronic (plastic) diary methods (see record 2006-03820-006) and hope that it will stimulate more balanced considerations of the issues involved. The authors begin by highlighting areas of agreement and disagreement with Green et al. The authors review briefly the broader literature that has compared paper and plastic diaries, noting how recent comparisons have relied on study designs and methods that favor investigators' allegiances. The authors note some sorely needed data for the evaluation of the implications of paper versus plastic for the internal and external validity of research. To facilitate evaluation of the existing literature and assist in the design of future studies, the authors offer a balanced comparison of paper and electronic diary methods across a range of applications. Finally, the authors propose 2 study designs that offer fair comparisons of paper and plastic diary methods. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Causal attribution, perceived benefits, and morbidity after a heart attack: An 8-year study.

In a sample of 287 heart attack victims who were interviewed 7 weeks and 8 years after their attack or who were known to have died during follow-up, interrelations among causal attributions for the attack, perceived benefits of the attack, survivor morbidity, and heart attack recurrence were explored. Analyses focused on early cognitive predictors of heart attack recurrence and 8-year morbidity and on the effects of surviving another heart attack on cognitive appraisals. Independently of sociodemographic characteristics and physicians' ratings of initial prognosis, patients who cited benefits from their misfortune 7 weeks after the first attack were less likely to have another attack and had lower levels of morbidity 8 years later. Attributing the initial attack to stress responses (e.g., worrying, nervousness) was also predictive of greater morbidity in 8-year survivors and blaming the initial attack on other people was predictive of reinfarctions. Men who survived a subsequent heart attack were more likely than men who did not have additional attacks to cite benefits and made more attributions 8 years after the initial attack. (37 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Examinations of chronic pain and affect relationships: Applications of a dynamic model of affect.

Two studies of the relationship between pain and negative affect are presented in this article: a study of weekly fluctuations in pain and negative affect among those with arthritis and a study of daily fluctuations in pain and negative affect for participants with fibromyalgia. The roles of positive affect and mood clarity (or the ability to distinguish between different emotions) in modifying the size of the relationship between pain and negative affect were examined in both studies as a means of testing the predictions of a dynamic model of affect regulation. In both studies, the presence of positive affect reduced the size of the relationship between pain and negative affect. Also, for arthritis participants with greater mood clarity, there was less overlap in ratings of negative and positive affective states. (PsycINFO Database Record (c) 2010 APA, all rights reserved)