Stereotype activation and control of race bias: Cognitive control of inhibition and its impairment by alcohol.

Two experiments tested the hypothesis that alcohol increases race-biased responding via impairment of self-regulatory cognitive control. Participants consumed either a placebo or alcohol and then made speeded responses to stereotypic trait words presented after White and Black face primes while behavioral and event-related brain potential (ERP) data were recorded. Alcohol did not affect stereotype activation in either experiment. Experiment 2 showed that alcohol significantly impaired the ability to inhibit race-biased responses but did not reliably influence control of counterstereotypic responses. This disinhibition appears driven by impairment of regulative cognitive control, as indexed by amplitude of the negative slow wave ERP component. These findings suggest that controlling racial bias can be a function of effective implementation of basic self-regulatory processes in addition to the motivational processes identified in other research. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Short- and long-term effects of fraternity and sorority membership on heavy drinking: A social norms perspective.

This study sought to determine whether the well-established relation between fraternity/sorority (Greek) membership and heavy alcohol use persists beyond the college years and whether some common third variables might account for the relation between Greek status and heavy drinking. During each of 4 years of college and 1 additional year, young adults (N ?=?319) completed measures of alcohol use, personality, alcohol expectancies, and environmental influences on drinking. Throughout the college years, Greeks consistently drank more heavily than non-Greeks. Statistically controlling for previous alcohol use did not eliminate this effect. However, Greek status did not predict postcollege heavy drinking levels. Also, perceived peer norms for heavy drinking mediated the relation between Greek affiliation and heavy alcohol use. Results are discussed in terms of situational determinants of heavy alcohol involvement in young adults. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of alcohol priming on social disinhibition.

Recent studies have suggested that exposure to rudimentary alcohol cues activates mental representations of alcohol expectancies in long-term memory, thereby promoting expectancy-consistent behavior changes. However, reliance in these previous studies on self-report measures raises the possibility that prior findings were an artifact of experimental demand. The present study was aimed at ruling out this alternative explanation by reinvestigating the effects of alcohol priming on nonconsumptive behavior using an implicit measure of social disinhibition. In three experiments, participants were exposed to either alcohol or control beverage images, then asked to type as quickly as possible the first word that came to mind in response to a series of provocative (e.g., feces) and neutral (e.g., chair) stimulus words. Participants’ response times were surreptitiously measured. Results revealed that participants exposed to images of alcohol, relative to control beverages, were faster to generate free associations to provocative, but not neutral, words, suggesting enhanced social disinhibition. This effect was limited to conditions of heightened evaluation, ruling out alternative explanations based on knowledge activation or arousal. Participants reported no suspicions regarding the connection between the image viewing and free association tasks nor any awareness that their response times had been collected. Results suggest that the behavioral effects of alcohol priming do not result from demand characteristics and offer the first evidence that exposure to rudimentary alcohol-related stimuli may suffice to influence social disinhibition in a manner akin to that expected to result from actual or placebo alcohol consumption. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Personality and substance use disorders: A prospective study.

The personality systems of Cloninger (as measured by the Tridimensional Personality Questionnaire [TPQ]) and Eysenck (as measured by the Eysenck Personality Questionnaire [EPQ]) both have been linked to substance use and abuse. The current study examined the predictive utility of both systems for substance use disorder (SUD) diagnoses, both cross-sectionally and prospectively. Participants (N?=?489 at baseline) completed the EPQ and TPQ and were assessed via structured diagnostic interview at baseline and 6 years later (N?=?457 at follow-up). Both the EPQ and TPQ scales demonstrated bivariate cross-sectional and prospective associations with SUDs. Within each system, those dimensions marking a broad impulsive sensation-seeking or behavioral disinhibition trait were the best predictors prospectively, although the 2 systems were differentially sensitive to specific diagnoses. These relations remained significant even with autoregressivity, other concurrent SUD diagnoses, and multiple personality dimensions statistically controlled. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of alcohol on person perception: A social cognitive neuroscience approach.

The acute effects of alcohol on cognitive processing of expectancy violations were investigated using event-related brain potentials and a cued recall task to index attentional and working memory processes associated with inconsistency resolution. As predicted, expectancy-violating behaviors elicited larger late positive potentials (LPP) and were recalled better than expectancy-consistent behaviors. These effects were moderated by alcohol and the valence of initial expectancies. For placebo group participants, positive targets performing negative behaviors elicited the largest LPP responses and were recalled best. For those in the alcohol groups, negative targets behaving positively elicited the largest LPP and recall responses. These findings suggest that alcohol does not globally impair working memory processes in person perception but instead changes the nature of valenced information processing. Findings are discussed in the context of alcohol's effects on working memory processes, reward sensitivity, and the prefrontal cortical structures thought to mediate them. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of alcohol sensitivity on P3 event-related potential reactivity to alcohol cues.

Although alcoholics and individuals at risk for alcoholism often show smaller amplitude of the P3 event-related brain potential (ERP), recent data (K. Namkoong, E. Lee, C. H. Lee, B. O. Lee, & S. K. An, 2004) indicate that alcohol-related cues elicit larger P3 amplitude in alcoholics than in controls. Little is known concerning the ERP profiles or alcohol cue reactivity of social drinkers at risk for alcoholism due to low sensitivity to alcohol's effects. Participants differing in alcohol sensitivity viewed images of alcoholic and nonalcoholic beverages while ERPs were recorded and provided information about their alcohol use patterns at baseline and 4 months later. Compared to high-sensitivity participants, those low in sensitivity showed larger P3s to alcohol cues, even when recent alcohol use was statistically controlled for. Moreover, the P3 elicited by alcohol cues predicted alcohol use at follow-up, a finding supporting the idea that P3 amplitude reflects the motivational significance of substance-related cues. These findings point to risk status, not consumption history, as an important predictor of cue reactivity effects. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Specificity of P3 event-related potential reactivity to alcohol cues in individuals low in alcohol sensitivity.

Recent research using event-related potentials (ERPs) has shown that individuals low in alcohol sensitivity show increased P3 reactivity to alcohol cues (Bartholow, Henry, & Lust, 2007). The current research sought to test the specificity of this effect by including other arousing cues in addition to alcohol, and by controlling for individual differences in trait impulsivity. Forty-seven participants varying in self-reported alcohol sensitivity completed a visual oddball task including neutral, arousing (erotic and adventure-related), and beverage-related images while ERPs were recorded. Low-sensitivity participants showed increased P3 reactivity to alcohol cues relative to their high-sensitivity peers. However, P3 amplitude elicited by all other targets did not differ as a function of alcohol sensitivity levels. Differences in impulsivity and recent alcohol consumption did not account for sensitivity group differences in alcohol cue reactivity. These results point to the specific motivational salience of alcohol cues to individuals at risk for alcohol problems because of low alcohol sensitivity and suggest that P3 reactivity to alcohol cues could be a new endophenotype for alcohol use disorder risk. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Stress-response-dampening effects of alcohol: Attention as a mediator and moderator.

The present study sought to characterize alcohol's stress-response-dampening (SRD) effects on multiple measures of stress and whether these effects are mediated by reductions in sustained attention and, further, whether baseline levels of sustained attention moderate SRD. One hundred six men consumed either an alcohol (0.70 g/kg) or a placebo beverage prior to learning that they would deliver a self-disclosing speech. Structural equation models controlling for multiple baseline periods indicated that alcohol directly reduced self-reported anxiety and skin conductance levels in response to the stressor. Alcohol's effect on reducing heart rate response, in contrast, was indirect and mediated by effects on prestress baseline. As hypothesized, differences in sustained attention partially mediated the effects of alcohol on skin conductance (but not heart rate or self-reported anxiety) and served as a moderator of alcohol's effects on skin conductance response. Findings are discussed in terms of theoretical links among alcohol consumption, specific cognitive abilities, and stress reactivity. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Interactive effects of alcohol outcome expectancies and alcohol cues on nonconsumptive behavior.

Experimental research and popular belief suggest that, among its many effects, alcohol consumption reduces tension and facilitates aggression. Such observations could result from direct, pharmacological effects of alcohol on neural control of behavior but also may be accounted for by positing that drinking behavior activates mental representations of relaxation-related or aggression-related alcohol expectancies in long-term memory. Building on this latter view, in 2 experiments, the authors investigated whether rudimentary drinking-related cues, which presumably activate encoded alcohol expectancies, facilitate tension reduction and hostility in the complete absence of actual or placebo alcohol consumption. In Experiment 1, following contextual exposure to alcohol-related words, individuals with stronger expectancies that drinking reduces tension showed an increased willingness to meet with an opposite-gender stranger under relatively anxiety-provoking circumstances, suggesting that they experienced less apprehension regarding the meeting. Analogously, in Experiment 2, following near-subliminal exposure to alcohol-related words, individuals with stronger expectancies that drinking fosters aggression showed greater hostility toward a target person following an experimentally engineered provocation. Neither of the latter effects was obtained following exposure to nonalcoholic beverage words, which presumably did not activate alcohol outcome expectancy representations in long-term memory. Moreover, the strength of relevant, content-specific expectancies (i.e., for tension reduction or aggression, respectively) moderated alcohol cue exposure effects, but the strength of other expectancies (e.g., for sociability or sexual arousal) did not. Together, these findings demonstrate that exposure to rudimentary alcohol cues independently engenders expectancy-consistent behavior, thereby attesting to the remarkable breadth and subtlety of the behavioral impact of alcohol expectancy activation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol Use and High-Risk Sexual Behavior Among Men Who Have Sex With Men: The Effects of Consumption Level and Partner Type.

Alcohol use may increase HIV sexual risk behavior, although findings have varied across study populations and methods. Using event-level data from 1,712 seronegative men who have sex with men, the authors tested the hypothesis that social context would moderate the effect of alcohol consumption on unprotected anal sex (UAS). For encounters involving a primary partner, rates of UAS did not vary as a function of alcohol use. However, consumption of 4 or more drinks tripled the likelihood of UAS for episodes involving a nonprimary partner. Thus, the effects of alcohol vary according to the context in which it is used. Interventions to reduce substance-related risk should be tailored to the demands of maintaining sexual safety with nonprimary partners. (PsycINFO Database Record (c) 2010 APA, all rights reserved)