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排序方式: 共有109条查询结果,搜索用时 46 毫秒
1.
Robert H. Doremus Denis Murphy Narottam P. Bansal William A. Lanford Chandra Burman 《Journal of Materials Science》1985,20(12):4445-4453
When liquid water contacts a zirconium-barium-lanthanum fluoride glass, at least three different processes occur. Barium and zirconium fluoride dissolve into the water, water penetrates into the glass, and zirconium fluoride crystals grow on the glass surface, in static solution. The rate of dissolution, as measured by solution analysis, is possibly controlled by diffusion in the solid surface; surface blockage and surface reactions are other possible kinetic steps involved. Diffusion in solution is not the controlling mechanism. Hydrogen profiles in the glass surface suggest that the penetration rate of water into the glass is controlled by diffusion and a surface reaction. 相似文献
2.
M Albert C Athanassopoulos LB Auerbach D Bauer R Bolton B Boyd RL Burman I Cohen DO Caldwell BD Dieterle JB Donahue AM Eisner A Fazely FJ Federspiel GT Garvey RM Gunasingha V Highland J Hill R Imlay K Johnston WC Louis A Lu AK Mann J Margulies K McIlhany W Metcalf RA Reeder V Sandberg M Schillaci D Smith I Stancu W Strossman MK Sullivan GJ VanDalen W Vernon YX Wang DH White D Whitehouse D Works Y Xiao S Yellin 《Canadian Metallurgical Quarterly》1995,51(3):R1065-R1069
3.
A statistically more reliable approach than the traditional visual inspection of peptide maps to identify a drug compound is to generate a set of reference standards from a designed experiment that incorporates many possible factors that affect variation of peptide mapping. In fact, the experiment can be done for a ruggedness study as part of a high-performance liquid chromatography (HPLC) method validation. Once the ruggedness is proved with the study, those articles in the experiment may form a set of reference standards, and future articles can be compared to the set later to prove identity. A quantitative analysis of the ruggedness study can be done using a chemometrics approach, principal component analysis (PCA). The analysis is used to reduce the many channels of peptide maps to a few manageable dimensions. The scores projected onto the reduced dimensions are used to test factor effects of the ruggedness study. As a by-product, the analysis provides visual inspection of the set of articles in the experiment for any outliers and anomalies. 相似文献
4.
SB Christensen A Guider CJ Forster JG Gleason PE Bender JM Karpinski WE DeWolf MS Barnette DC Underwood DE Griswold LB Cieslinski M Burman S Bochnowicz RR Osborn CD Manning M Grous LM Hillegas JO Bartus MD Ryan DS Eggleston RC Haltiwanger TJ Torphy 《Canadian Metallurgical Quarterly》1998,41(6):821-835
Evaluation of a variety of PDE4 inhibitors in a series of cellular and in vivo assays suggested a strategy to improve the therapeutic index of PDE4 inhibitors by increasing their selectivity for the ability to inhibit PDE4 catalytic activity versus the ability to compete for high affinity [3H]rolipram-binding sites in the central nervous system. Use of this strategy led ultimately to the identification of cis-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxyl ic acid (1, SB 207499, Ariflo), a potent second-generation inhibitor of PDE4 with a decreased potential for side effects versus the archetypic first generation inhibitor, (R)-rolipram. 相似文献
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This letter deals with the propagation of coupled electromagnetic and electroacoustic waves in a magnetised compressible continuously stratified electron plasma. Some first-order coupled-wave equations are derived. 相似文献
8.
Often, in practice, one may regard an observed time series as being composed of a function that is smooth over years, with additive seasonal effects. As a modification, we formulate a particular multiplicative model that expresses the observed data as a yearly trend function with additive amplitude-modulated seasonal factors. Without smoothness restrictions on the yearly trend and modulation components, the least squares solutions for the seasonal components are shown to be proportional to the eigenvector corresponding to the maximum eigen value of the within-season covariance matrix. If the trend and seasonal modulations are modeled as smooth splines, we give the comparable estimators for the smooth functions and the seasonal factors. We show consistency for the trend, modulation and seasonal factors as well as asymptotic normality for the seasonal estimates. Model selection, fitting and forecasting are considered for a quarterly earnings series that exhibits extreme nonlinear and nonstationary behavior. We compare the results with those obtained using a competing nonstationary multiplicative ARIMA model 相似文献
9.
Bradley Katharine A.; Bush Kristen R.; Davis Tania M.; Dobie Dorcas J.; Burman Marcia L.; Rutter Carolyn M.; Kivlahan Daniel R. 《Canadian Metallurgical Quarterly》2001,15(4):297
This study evaluated the prevalence and associated risks of binge drinking, defined as having ≥4 drinks on an occasion in the past year, in a female patient population. Of 1,259 female Veterans Affairs patients surveyed, 780 reported drinking alcohol in the past year, and 305 (24% of respondents, 39% of drinkers) reported binge drinking in the past year; 84 (11% of drinkers) had done so monthly or more often. Age-adjusted logistic regression analyses indicated that women who reported past-year binge drinking monthly or more often reported significantly increased odds of morning drinking (odds ratio [OR]?=?40.3), others worrying about their drinking (OR?=?38.6), arguments after drinking (OR?=?13.5), hepatitis or cirrhosis (OR?=?3. 1), frequent injuries (OR?=?2.6), smoking (OR?=?3.7), drug use (OR?=?22.2), and multiple sexual partners (OR?=?4.6). (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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