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1.
M Kay R Wyllie W Michener M Caulfield R Steffen 《Canadian Metallurgical Quarterly》1993,60(6):473-478
We report two young men with clinical and laboratory evidence of macroscopic ulcerative colitis, sclerosing cholangitis, and insulin-dependent diabetes mellitus. The first patient presented at age 15 with vomiting, abdominal pain, weight loss, and abnormal liver function test results. Liver biopsy and endoscopic retrograde cholangiopancreatography (ERCP) demonstrated sclerosing cholangitis. Colonoscopy with biopsy revealed ulcerative colitis which responded to sulfasalazine. Diabetes occurred at age 18 and insulin therapy was begun. The second patient was 19 at presentation with diarrhea, hematochezia, and weight loss. Proctosigmoidoscopy revealed ulcerative colitis, and sulfasalazine led to clinical remission. Three months later he developed diabetes requiring insulin therapy. At age 28, he developed elevated alkaline phosphatase, and ERCP revealed sclerosing cholangitis. At age 37 he expired from adenocarcinoma that metastasized to the liver. Literature review revealed only one possible case report of this association with microscopic asymptomatic ulcerative colitis in that patient. Statistical analysis suggests that this association is real rather than a chance occurrence. An autoimmune process may be involved and a specific histocompatibility locus antigen (HLA) type may exert a regulatory influence. 相似文献
2.
DiPietro Janet A.; Caulfield Laura E.; Irizarry Rafael A.; Chen Ping; Merialdi Mario; Zavaleta Nelly 《Canadian Metallurgical Quarterly》2006,120(3):687
Fetal and maternal data were monitored serially at 6 gestational ages from 20 to 38 weeks in 195 Peruvian fetuses. Digitized data included fetal heart rate and motor activity, as well as maternal heart rate and electrodermal conductance. Time series analysis evaluated the development of synchrony in 2 streams of fetal functioning and between mothers and fetuses. Intrafetal synchrony between heart rate and motor activity developed in an orderly fashion, with peak cross-correlation approaching an asymptote at 5 s at 28 weeks. Synchrony was not observed between fetal heart rate and maternal measures. Fetal motor activity exhibited synchrony with both maternal electrodermal and heart rate activity. Implications for revealing fundamental properties of neural development prior to birth are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
3.
DiPietro Janet A.; Caulfield Laura; Costigan Kathleen A.; Merialdi Mario; Nguyen Ruby H. N.; Zavaleta Nelly; Gurewitsch Edith D. 《Canadian Metallurgical Quarterly》2004,40(3):445
Longitudinal neurobehavioral development was examined in 237 fetuses of low-risk pregnancies from 2 distinct populations-Baltimore, Maryland, and Lima. Peru-at 20. 24. 28. 32, 36. and 38 weeks gestation. Data were based on digitized Doppler-based fetal heart rate (FHR) and fetal movement (FM). In both groups. FHR declined while variability, episodic accelerations, and FM-FHR coupling increased, with discontinuities evident between 28 and 32 weeks gestation. Fetuses in Lima had higher FHR and lower variability, accelerations, and FM-FHR coupling. Declines in trajectories were typically observed 1 month sooner in Lima, which magnified these disparities. Motor activity differences were less consistent. No sex differences in fetal neurobehaviors were detected. It is concluded that population factors can influence the developmental niche of the fetus. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
4.
5.
Koczor Sándor Vuts József Caulfield John C. Withall David M. Sarria André Pickett John A. Birkett Michael A. Csonka Éva Bálintné Tóth Miklós 《Journal of chemical ecology》2021,47(6):525-533
Journal of Chemical Ecology - The sex pheromone composition of alfalfa plant bugs, Adelphocoris lineolatus (Goeze), from Central Europe was investigated to test the hypothesis that insect species... 相似文献
6.
In a number of prior papers we described and explored a new pattern recognition method called Margin-Setting that accomplishes
excellent generalization using very few training samples. The result was a multi-round classifier with each round consisting
of a set of hyperspheres such that if a datum fell within a certain hypersphere, it was labeled with one particular class.
Margin-Setting achieves concurrent low Vapnik-Chervonenkis (VC) dimension and high accuracy which is a consequence of partitioning
the training set into smaller sets that make this possible. This paper extends Margin-Setting from hyperspheres to hyperellipsoids
resulting in improved performance. 相似文献
7.
Bacteria in a water‐damaged building: associations of actinomycetes and non‐tuberculous mycobacteria with respiratory health in occupants
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J.‐H. Park J. M. Cox‐Ganser S. K. White A. S. Laney S. M. Caulfield W. A. Turner A. D. Sumner K. Kreiss 《Indoor air》2017,27(1):24-33
We examined microbial correlates of health outcomes in building occupants with a sarcoidosis cluster and excess asthma. We offered employees a questionnaire and pulmonary function testing and collected floor dust and liquid/sludge from drain tubing traps of heat pumps that were analyzed for various microbial agents. Forty‐nine percent of participants reported any symptom reflecting possible granulomatous disease (shortness of breath on exertion, flu‐like achiness, or fever and chills) weekly in the last 4 weeks. In multivariate regressions, thermophilic actinomycetes (median = 529 CFU/m2) in dust were associated with FEV1/FVC [coefficient = ?2.8 per interquartile range change, P = 0.02], percent predicted FEF25–75% (coefficient = ?12.9, P = 0.01), and any granulomatous disease‐like symptom [odds ratio (OR) = 3.1, 95% confidence interval (CI) = 1.45?6.73]. Mycobacteria (median = 658 CFU/m2) were positively associated with asthma symptoms (OR = 1.5, 95% CI = 0.97?2.43). Composite score (median = 11.5) of total bacteria from heat pumps was negatively associated with asthma (0.8, 0.71?1.00) and positively associated with FEV1/FVC (coefficient = 0.44, P = 0.095). Endotoxin (median score = 12.0) was negatively associated with two or more granulomatous disease‐like symptoms (OR = 0.8, 95% CI = 0.67?0.98) and asthma (0.8, 0.67?0.96). Fungi or (1→3)‐β‐D‐glucan in dust or heat pump traps was not associated with any health outcomes. Thermophilic actinomycetes and non‐tuberculous mycobacteria may have played a role in the occupants' respiratory outcomes in this water‐damaged building. 相似文献
8.
Optical neural networks 总被引:2,自引:0,他引:2
Caulfield H.J. Kinser J. Rogers S.K. 《Proceedings of the IEEE. Institute of Electrical and Electronics Engineers》1989,77(10):1573-1583
Classical optical information processing and classical neural networks can be adapted and combined to create optical neural networks which offer significant and fundamental advantages over electronic neural networks in various well-defined cases. A systematic morphology of optical neural networks is presented. Special problems they create are discussed. The state of the art of their implementation is indicated, and some supportable speculations on their future are given 相似文献
9.
Nils H. Abramson Hans I. Bjelkhagen H. John Caulfield 《Journal of Modern Optics》2013,60(7):1399-1406
Abstract After placing prior work on time-gated holography and coherence-gated holography in a unified perspective, we broaden both with a new coherence theorem which introduces an assymetry between them and allows otherwise-impossible holograms to be formed. 相似文献
10.