The day of the week when you were born in 700 ms: Calendar computation in an autistic savant.

Some individuals are able to determine the weekday of a given date in a few seconds (finding for instance that June 12, 1900, was a Tuesday). This ability has fascinated scientists for many years because it is predominantly observed in people with limited intelligence and may appear very early in life. Exceptional visual memory, exceptional concentration abilities, or privileged access to lower levels of information not normally available through introspection have been advanced to explain such phenomena. In the present article, the authors show that a simple cognitive model can explain all aspects of the performance of Donny, a young autistic savant who is possibly the fastest and most accurate calendar prodigy ever described. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Using bald eagles to indicate the health of the Great Lakes' environment

The bald eagle (Haliaeetus leucocephalus) is one of the most studied birds of North America, and a great amount of natural life‐history information, including the response of various stressors on the eagles' ability to reproduce, are well known. In Michigan, the eagle has been chosen to track the trends of bioaccumulative compounds of concern across watersheds in the state. The state has been divided into major watersheds, and 20% of these are surveyed each year. A control area in northern Minnesota, Voyageurs National Park, is also sampled annually. We report here on the methods used, the preliminary results of the 1999 field season, and how differences in mercury concentrations varied over a 10‐year period. Mercury in feathers of nestling eagles declined over time only in Lakes Michigan and Huron, but have not decreased among other subpopulations in Michigan. Concentrations of polychlorinated biphenyls (PCBs) and 4,4′‐DDE in blood plasma from nestling eagles have declined over time for most subpopulations; however, they remain greater for breeding areas associated with the Great Lakes' food web. Sea eagles of the genus Haliaeetus are a good sentinel species to track trends in bioaccumulative compounds in aquatic systems.     

Comment on Greenwood (2007): Solving the puzzle of structure/function relations in the aging brain?

Neuroimaging experiments have shown that prefrontal regions of the brain, which have the most age-related volume loss, are also the regions most likely to be more active in older adults than in younger adults. In an attempt to solve this puzzle, P. M. Greenwood (see record 2007-15625-001) has proposed a cascade that flows from age-related atrophy in the brain to changed processing strategies that result in plastic changes in regions adjacent and contralateral to the atrophic areas, culminating in greater functional activity. This hypothesis should stimulate research into these mechanisms and hopefully will ultimately inform researchers' ability to rehabilitate cognitive disorders in the elderly. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Paget's disease of the breast in a man without underlying breast carcinoma

A case of histologically confirmed Paget's disease of the breast in a 72 year old man, without underlying breast carcinoma, is reported. This report raises questions about the pathogenesis of this condition and suggests that Paget's disease is an independent, intraepidermal carcinoma rather than a direct extension of intraductal carcinoma of the breast to the nipple and areola.     

Methods used in dentin bonding tests: an analysis of 50 investigations on bond strength

Researchers have carried out a variety of investigations to determine the properties of available dentin bonding systems. The test methods and variables used in 50 published investigations of bond strength were analyzed. Among the studies analyzed, shear tests predominated, being used in 80% of the studies; dentin from human molar teeth was used most often (in 88% of investigations); and the most prevalent time of testing was 24 hours postcuring. However, a number of potential variables were not recorded in a high proportion of articles, among these the film thickness, the type of dentin tested, and the surface condition (moist or dry). The mode of failure was recorded in only 42% of the investigations assessed. It was found that there is little standardization of test methods in studies of dentin bond strength and that a number of variables are often either not recorded or reported.     

Vertebral artery trauma

The developmental consequences of paternal exposure to acrylamide (50 mg/kg i.p. for 5 days) were assessed in preimplantation embryos. There was a significant increase in the proportion of morphologically abnormal embryos after postmeiotic treatment during spermatogenesis (88.7% vs. 14.8% in control). Abnormal embryos had an average of 1.8 +/- 3.5 cells and > 80% had at least one fragmented nucleus. In addition, morphologically normal embryos were significantly delayed (34.3 +/- 12.8 cells per embryo vs. 57.6 +/- 15.7 in control, P < 0.001). Acrylamide caused 10- and 20-fold increases in frequencies of cells with micronuclei (MN) in morphologically normal and abnormal embryos, respectively (41 and 93 MN per 1,000 cells). Both centromere-negative (MN-) and centromere-positive (MN+) were induced. Nuclei of abnormal embryos were significantly larger (900 microm2 vs. 250 microm2) than controls. In addition, MN of abnormal embryos were larger than those of normal embryos (21.2 microm2 vs. 6.5 microm2, P < 0.01). Among control embryos, MN+ were significantly larger than MN- (P < 0.05). These findings suggest that the preimplantation embryo is a sensitive indicator of paternally transmitted effects on early development. Multiple mechanisms appear to be involved, including cytogenetic damage, proliferation arrest/delay, and fertilization failure. Future studies are needed to establish how induced cytological defects in preimplantation embryos contribute to birth defects and other postimplantation abnormalities.     

A high-current and high-temperature 6H-SiC thyristor

A 6H-SiC thyristor has been fabricated and characterized. A forward breakover voltage close to 100 V and a pulse switched current density of 5200 A/cm² have been demonstrated. The thyristor is shown to operate under pulse gate triggering for turn-on and turn-off, with a rise time of 43 ns and a fall time of less than 100 ns. The forward breakover voltage is found to decrease by only 4% when the operating temperature is increased from room temperature to 300°C. It is found that anode ohmic contact resistance dominates the device forward drop at high current densities     

Why do semantic priming effects increase in old age? A meta-analysis.

Reports a meta-analysis comparing the size of semantic priming effects on young and older adults' lexical decision and pronunciation latency. The analysis included 15 studies with 49 conditions varying the semantic relatedness of a prime stimulus (single word or whole sentence) and a target word. An effect-size analysis on the difference between young and older adults' semantic priming effect (unrelated minus related latency) indicated that semantic priming effects are reliably larger for older than for young adults. There was no evidence for nonhomogeneity in this age difference across the different conditions. The relationship between young and older adults' semantic priming effects was described by a function with a positive intercept and a slope of 1.0. This pattern of findings favors aging models postulating process-specific slowing rather than general cognitive slowing. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychosocial characteristics of adolescents who refuse cancer treatment.

Examined psychosocial variables by comparing 10 13–17 yr old adolescents (and their mothers) who had refused cancer treatment with a group of 10 consenting adolescents who were matched on age and demographic and illness variables. Adolescents completed the State-Trait Anxiety Inventory for Children and measures of family characteristics, locus of control, religion, hopelessness, impact of event, and satisfaction with physician. Mothers completed the State-Trait Anxiety Inventory and measures of coping and religion. Adolescent refusers scored lower on state anxiety and subjective distress but scored higher on trait anxiety, religiosity, and external locus of control. Their mothers also scored higher than did the consenting-group mothers on religiosity and trait anxiety. It is suggested that refusers are prone to anxiety and cope with their present distress by maintaining the belief that their lives are determined by fate or religious convictions. An intervention approach that fosters mastery over the cancer experience is advocated. (8 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)