供水管网DMA优化分区设计方案

实施独立计量分区(district metered area,DMA)是辅助供水管网管理和漏损识别的重要手段.图划分算法是进行DMA分区的方法之一,常规图划分算法应用中,存在解空间受限、分区后原水流状态易发生较大改变、形成较多串联分区(对流量计算不利)的缺点.在常规图划分算法基础上进行了改进:粗化阶段按照特定规则匹配、合并非输水干管两端的节点,形成简化的管网拓扑结构;分区阶段得到管网初步分区方案;细化阶段提出基于贪心算法、枚举算法、蒙特卡洛算法的分区调整方法,结合改进的仪表安置方法、水力模拟、优劣解距离法(technique for order preference by similarity to an ideal solution,TOPSIS),对分区方案进行调整.将该方法应用于YX市供水管网,成功进行了分区.     

Expression of Main Toll-Like Receptors in Patients with Different Types of Colorectal Polyps and Their Relationship with Gut Microbiota

Abnormal activation of Toll-like receptor (TLRs) signaling can result in colon cancer development. The aim of this study was to investigate the expression of important TLRs in different histological types of colorectal polyps and evaluate their relationship with intestinal microbiota. The expression levels of TLR2, 3, 4, and 5 were analyzed in intestinal biopsy specimens of 21 hyperplastic polyp (HP), 16 sessile serrated adenoma (SSA), 29 tubular adenoma (TA), 21 villous/tubulovillous (VP/TVP) cases, and 31 normal controls. In addition, selected gut bacteria including Streptococcus bovis, Enterococcus faecalis, Enterotoxigenic Bacteroides fragilis (ETBF), Fusobacterium nucleatum, Porphyromonas spp., Lactobacillus spp., Roseburia spp., and Bifidobacterium spp. were quantified in fecal samples using absolute qRT PCR, and, finally, the association between TLRs and these gut microbiota- was evaluated by Spearman’s correlation coefficient. Higher expression of TLR2 and TLR4 in VP/TVP and TA, and lower expression levels of TLR3 and TLR5 in all type of polyps were observed. The differences in TLR expression patterns was not only dependent on the histology, location, size, and dysplasia grade of polyps but also related to the intestinal microbiota patterns. TLR2 and TLR4 expression was directly associated with the F. nucleatum, E. faecalis, S. bovis, Porphyromonas, and inversely to Bifidobacterium, Lactobacillus, and Roseburia quantity. Furthermore, TLR3 and TLR5 expression was directly associated with Bifidobacterium, Roseburia, and Lactobacillus quantity. Our results suggest a possible critical role of TLRs during colorectal polyp progression. An abnormal regulation of TLRs in relation to gut microbial quantity may contribute to carcinogenesis.     

基于高频损耗比的干式空心电抗器制造缺陷检测方法及应用探讨

本文通过分析电抗器因制造工艺导致少匝和极限工艺偏差时600Hz损耗,提出高频损耗可作为电抗器制造缺陷的检测手段及其适用范围,并以600Hz的实测损耗与理论损耗之比是否超过1.5作为判据,以同组任两台损耗之比是否超过1.5作为辅助判据,同时列举应用实例.     

安家岭露天矿过采空区危险源辨识及安全措施研究

危险源辨识对提高煤矿安全生产具有重要的现实意义。研究建立了基于层次分析法的安家岭露天矿危险源辨识模型,确定了危险源指标的权重。依据危险源辨识的权重研究了安家岭露天矿过采空区安全开采存在的主要危险源,并把采空区分为高温明火采空区、积水采空区、存在有毒气体的采空区、未冒实采空区,针对不同的类别的采空区提出了相应的安全开采措施。     

马钢张庄矿高压辊磨机装配工艺研究

针对马钢张庄矿高压辊磨机辊套疲劳断裂严重、对辊精度不能满足生产要求等问题，马钢重机公司根据张庄矿实际生产要求对对辊进行国产化，国产化内容包括辊轴、辊套等零部件的新制以及装配工艺攻关，通过技术研发同时结合实际生产经验，成功对高压辊磨机辊套与辊轴以及辊轴与轴承进行装配，完成了张庄矿高压辊磨机整对对辊的国产化，为该型设备后续生产及优化提供了理论和实践参考依据。     

一种CMOS静态双沿顺序脉冲发生器的设计

提出一种基于CMOS技术的静态双沿顺序脉冲发生器结构。他是由以基于CMOS二选一选择器的电平型触发器构成的记忆单元和一个与门阵列组成的转译单元构成的。与门阵列的转译单元使顺序脉冲发生器在时钟上升沿和下降沿处均能输出移位脉冲,从而形成双沿触发的功能。仿真验证其功能正确,且根据分析该结构不仅能够节省芯片面积,还可以大大减小芯片的功耗。     

Profile-Driven Component Placement for Cluster-Based Online Services

The growth of the Internet and of various intranets has spawned a wealth of online services, most of which are implemented on local-area clusters using remote invocation (for example, remote procedure call/remote method invocation) among manually placed application components. Component placement can be a significant challenge for large-scale services, particularly when application resource needs are workload dependent. Automatic component placement has the potential to maximize overall system throughput. The key idea is to construct (offline) a mapping between input workload and individual-component resource consumption. Such mappings, called component profiles, then support high-performance placement. Preliminary results on an online auction benchmark based on J2EE (Java 2 Platform, Enterprise Edition) suggest that profile-driven tools can identify placements that achieve near-optimal overall throughput.