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1.
The application of titanium dioxide (TiO(2)) films as surgical implant coatings for antibiotic attachment depends crucially on their available surface area and thus their surface morphology and crystallinity. Here, we report our fabrication of high Wenzel ratio TiO(2) films targeted to increase the film surface area using the ion beam-assisted deposition (IBAD) technique at high-deposition temperatures (approximately 610 degrees C). The modulation of the films' surface morphology was accomplished by varying the chemical identity of the concurrent ion beams bombarded on the films during the e-beam evaporation process. Atomic force microscopy (AFM) and scanning electron microscopy (SEM) were employed to investigate the surface morphology of the as-deposited films. X-ray diffractometry (XRD) revealed that these nanocrystalline films primarily consist of anatase phase TiO(2). Wenzel ratio, the ratio of the actual surface area to the projected area, of IBAD films prepared with argon, oxygen, and nitrogen ion beams was measured to be 1.52, 1.31 and 1.49, respectively. The effect of the differences in chemical reactivity and ion size of these three type ion beams are discussed to explain the present results. 相似文献
2.
Barrera OA Haider H Garvin KL 《Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine》2008,222(1):63-74
Arthroplasty outcome is influenced by the 'quality' of bone preparation for implant insertion. Surgeons face increasing choices of technique and instrumentation, yet clinical scoring methods assess the overall outcome and patient satisfaction but not the bone cuts directly. 'Quality management' of bone reshaping is needed to evaluate different bone cutting methods and computer assisted orthopaedic surgery (CAOS) systems. Analyses and experiments in this study were formulated for measurement and computation of four quantitative characteristics of bone preparation 'quality' and produced a highly condensed index for each. These represented (a) surface finish of cuts, (b) implant fit/looseness possible with the cut shape, (c) implant location/misalignment, and (d) accuracy of individual planar cuts. Assessment of synthetic bone cuts verified the robustness of the method for wide application in arthroplasty intraoperatively, in vitro and for comparing navigation systems. 相似文献
3.
Combinatorial interaction testing (CIT) is a cost-effective sampling technique for discovering interaction faults in highly-configurable
systems. Constrained CIT extends the technique to situations where some features cannot coexist in a configuration, and is
therefore more applicable to real-world software. Recent work on greedy algorithms to build CIT samples now efficiently supports
these feature constraints. But when testing a single system configuration is expensive, greedy techniques perform worse than
meta-heuristic algorithms, because greedy algorithms generally need larger samples to exercise the same set of interactions.
On the other hand, current meta-heuristic algorithms have long run times when feature constraints are present. Neither class
of algorithm is suitable when both constraints and the cost of testing configurations are important factors. Therefore, we
reformulate one meta-heuristic search algorithm for constructing CIT samples, simulated annealing, to more efficiently incorporate
constraints. We identify a set of algorithmic changes and experiment with our modifications on 35 realistic constrained problems
and on a set of unconstrained problems from the literature to isolate the factors that improve performance. Our evaluation
determines that the optimizations reduce run time by a factor of 90 and accomplish the same coverage objectives with even
fewer system configurations. Furthermore, the new version compares favorably with greedy algorithms on real-world problems,
and, though our modifications were aimed at constrained problems, it shows similar advantages when feature constraints are
absent. 相似文献
4.
Tang L Garvin MK Lee K Alward WL Kwon YH Abràmoff MD 《IEEE transactions on pattern analysis and machine intelligence》2011,33(11):2245-2258
A robust multiscale stereo matching algorithm is proposed to find reliable correspondences between low contrast and weakly textured retinal image pairs with radiometric differences. Existing algorithms designed to deal with piecewise planar surfaces with distinct features and Lambertian reflectance do not apply in applications such as 3D reconstruction of medical images including stereo retinal images. In this paper, robust pixel feature vectors are formulated to extract discriminative features in the presence of noise in scale space, through which the response of low-frequency mechanisms alter and interact with the response of high-frequency mechanisms. The deep structures of the scene are represented with the evolution of disparity estimates in scale space, which distributes the matching ambiguity along the scale dimension to obtain globally coherent reconstructions. The performance is verified both qualitatively by face validity and quantitatively on our collection of stereo fundus image sets with ground truth, which have been made publicly available as an extension of standard test images for performance evaluation. 相似文献
5.
Garvin T. Dreger 《Building Research & Information》2013,41(6):337-341
Professor Dreger of the College of Architecture at the Georgia Institute of Technology highlights the synergistic effect of the discrete conditions which individually contributed to the failure of the exterior stucco cladding system of the newly completed US$35 million Justice Center in Fort Myers, Florida in March 1985. He discusses the severe corrosion of the metal fixing components, the high level of water‐soluble chlorides, and the phenomena of both ‘stress corrosion’ and ‘crevice corrosion’. 相似文献
6.
KP Papadopoulos JH Garvin M Fetell LT Vahdat TJ Garrett DG Savage C Balmaceda J Bruce M Sisti S Isaacson R De LaPaz R Hawks E Bagiella KH Antman CS Hesdorffer 《Canadian Metallurgical Quarterly》1998,22(7):661-667
The prognosis in patients with primary brain tumors treated with surgery, radiotherapy and conventional chemotherapy remains poor. To improve outcome, combination high-dose chemotherapy (HDC) has been explored in children, but rarely in adults. This study was performed to determine the tolerability of three-drug combination high-dose thiotepa (T) and etoposide (E)-based regimens in pediatric and adult patients with high-risk or recurrent primary brain tumors. Thirty-one patients (13 children and 18 adults) with brain tumors were treated with high-dose chemotherapy: 19 with BCNU (B) and TE (BTE regimen), and 12 with carboplatin (C) and TE (CTE regimen). Patients received growth factors and hematopoietic support with marrow (n = 15), peripheral blood progenitor cells (PBPC) (n = 11) or both (n = 5). The 100 day toxic mortality rate was 3% (1/31). Grade III/IV toxicities included mucositis (58%), hepatitis (39%) and diarrhea (42%). Five patients had seizures and two had transient encephalopathy (23%). All patients had neutropenic fever and all pediatric patients required hyperalimentation. Median time to engraftment with absolute neutrophil count (ANC) >0.5 x 10(9)/l was 11 days (range 8-37 days). Time to ANC engraftment was significantly longer (P = 0.0001) in patients receiving marrow (median 14 days, range 10-37) than for PBPC (median 9.5 days, range 8-10). Platelet engraftment >50 x 10(9)/l was 24 days (range 14-53 days) in children. In adults, platelet engraftment >20 x 10(9)/l was 12 days (range 9-65 days). In 11 patients supported with PBPC, there was a significant inverse correlation between CD34+ dose and days to ANC (rho = -0.87, P = 0.009) and platelet engraftment (rho = -0.85, P = 0.005), with CD34+ dose predicting time to engraftment following HDC. Overall, 30% of evaluable patients (7/24) had a complete response (CR) (n = 3) or partial response (PR) (n = 4). Median time to tumor progression (TTP) was 7 months, with an overall median survival of 12 months. These TE-based BCNU or carboplatin three-drug combination HDC regimens are safe and tolerable with promising response rates in both children and older adults. 相似文献
7.
8.
9.
Centerbar David B.; Schnall Simone; Clore Gerald L.; Garvin Erika D. 《Canadian Metallurgical Quarterly》2008,94(4):560
In five studies, the authors examined the effects on cognitive performance of coherence and incoherence between conceptual and experiential sources of affective information. The studies crossed the priming of happy and sad concepts with affective experiences. In different experiments, these included approach or avoidance actions, happy or sad feelings, and happy or sad expressive behaviors. In all studies, coherence between affective concepts and affective experiences led to better recall of a story than did affective incoherence. The authors suggest that the experience of such experiential affective cues serves as evidence of the appropriateness of affective concepts that come to mind. The results suggest that affective coherence has epistemic benefits and that incoherence is costly in terms of cognitive performance. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
10.
Examined the concept of salience (ease of localization) in 4 experiments, using 43 undergraduates. A test of the relative salience of stimuli used in Exps 2–4 was conducted in Exp 1. Exp 2 showed that a designated target (an H or a column of Hs) was used as the standard against which the designated standard for localization (a line end) was judged when the former was more salient than the latter. Exp 3 showed that thin lines similar to those in Exp 2 were judged as shorter than they were, which suggests a mislocalization toward fixation. In Exp 4, when standards covered the entire display background, a single H (but not columns of Hs) was mislocalized toward fixation. (French abstract) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献