Medical-grade acrylic adhesives for skin contact

Pressure-sensitive acrylic adhesives for application to skin are made from 2-ethylhexyl acrylate, isooctyl acrylate or n-butyl acrylate copolymerized with polar functional monomers such as acrylic acid, methacrylic acid, vinyl acetate, methyl acrylate, N-vinylcaprolactam, or hydroxyethyl methacrylate. Functional comonomers increase cohesive strength, provide surface polarity, and enhance wear performance. Tack, adhesion to skin, adhesive transfer to skin, and wear performance of the adhesive are governed by the molecular weight, glass transition temperature, and the viscoelastic behavior of the adhesive. Viscoelastic properties of the adhesive as measured by the Williams plasticity number (WPN), dynamic storage modulus (G′), dynamic loss modulus (G″), and tan δ are important polymer properties for good wear performance. Sweating skin, a moist environment, and physical activity are the most important factors influencing the failure of an adhesive tape during wear. A medicalgrade adhesive for application to human skin should be hypoallergenic. Medical-grade adhesives are utilized in making surgical tapes for holding dressings in place, adhesive bandages, adhesive dressings to cover wounds, and surgical operating drapes.     

Speech-as-data technologies for personal information devices

 For small, portable devices, speech input has the advantages of low-cost and small hardware, can be used on the move or whilst the eyes & hands are busy, and is natural and quick. Rather than rely on imperfect speech recognition we propose that information entered as speech is kept as speech and suitable tools are provided to allow quick and easy access to the speech-as-data records. This paper summarises our work on the technologies needed for these tools – for organising, browsing, searching and compressing the stored speech. These technologies go a long way towards giving stored speech the characteristics of text without the associated input problems. Received: 5 March 2002 / Accepted: 1 September 2002 Nick Haddock Consultant Acknowledgements The authors would like to thank the whole HP Labs Gryphon team for their valuable contributions to this work - Mike Collins for the hierarchical chunking algorithm, Erik Geelhoed and David Frohlich for the users perspective, Richard Hull for starting off the compression work, Steve Loughran for productisation, and Dave Reynolds for his consistent advice and support. We would also like to thank our partners at Cambridge University, Steve Young and Tony Robinson, whose expertise and technology formed the foundation for this work, as well as the efforts of Kate Knill on wordspotting, Carl Seymour on compression, James Christie on recognition, and Robin Valenza whose brief excursion into the world of speech technology helped develop a simple and effective summarisation technique. Finally we would like to thank the reviewers for their many helpful comments.     

Efficacy of a tailored tobacco control program on long-term use in a population of U.S. Military troops.

The authors evaluated the effect of a brief tailored smoking control intervention delivered during basic military training on tobacco use in a population of military personnel (N = 33,215). Participants were randomized to either a tobacco use intervention (smoking cessation, smokeless tobacco use cessation, or prevention depending on tobacco use history) or a health education control condition. Results indicated that smokers who received intervention were 1.16 (95% confidence interval [CI] = 1.04, 1.30) times (7-day point prevalence) and 1.23 (95% CI = 1.07, 1.41) times (continuous abstinence) more likely to be abstinent than controls from smoking cigarettes at the 1-year follow-up (p p     

Angular-scattering characteristics of ferroelectric liquid-crystal electro-optical devices operating in the transient-scattering and the extended-scattering modes

The angular distribution of forward-scattered light in transient-scattering-mode (TSM) and extended-scattering-mode (ESM) ferroelectric liquid-crystal (FLC) devices was evaluated by use of circularly polarized incident light. For both modes the intensity and the distribution of forward-scattered light depended primarily on the FLC birefringence, spontaneous polarization, and the cell path length. In the FLC materials examined, the forward-scattering intensity under ESM drive conditions increased with longer FLC pitch lengths, whereas under TSM conditions stronger forward scattering was observed with increasing FLC spontaneous polarization. Although both TSM and ESM drive conditions displayed a similar angular distribution for forward-scattered light, the intensity of ESM scattering over a 0 degrees -6 degrees range was considerably smaller than that observed in earlier experiments with linearly polarized incident light.     

Fluctuation statistics of millimeter-wave scattering fromdistributed targets

The applicability of the Rayleigh fading model for characterizing radar scattering from terrain is examined at 35 GHz for both backscattering and bistatic scattering. The model is found to be in excellent agreement with experimental observations for single-frequency observations of uniform targets such as asphalt and snow-covered ground. The use of frequency averaging to reduce signal fading variations was examined experimentally by sweeping the radar signal from 34-36 GHz in 401 steps. The results show that the formulation based on the Rayleigh model relating the reduction in signal fluctuation to the bandwidth used provides a reasonable estimate for the improvement provided by frequency averaging     

An analysis of messages about tobacco in the Military Times magazines.

The Military Times magazines are seen as an independent source of news and information on the military and are widely read by military members. Given the influence of Military Times as a powerful media outlet within the military and marketing to military personnel by the tobacco industry, we examined tobacco messages and advertisements in a one-year sample from each service. No advertisements for cigarettes or other forms of smoked tobacco were found in any issue published in 2005. However, smokeless tobacco products were advertised frequently, with 11 distinct ads occurring in 105 ad placements. During the year targeted in the present study, smokeless tobacco advertising generated approximately US$564,249 in revenue for the publishers of Military Times. A content analysis suggested that the advertisements intended to pair smokeless tobacco use with a pleasant mood and enjoyable events not directly associated with the product itself. In addition, magazine articles about anti-tobacco topics received among the lowest amount of coverage among all pro-health articles. These findings may partially explain the recent significant increase in smokeless tobacco use among military personnel.     

Relationship between psychosocial functioning and body fat in preschool children: A longitudinal investigation.

Examined whether preschool children differed on measures of psychosocial functioning both cross-sectionally and longitudinally. 132 children who varied in levels of body fat participated in the study along with their natural parents. Results indicated that the children did not differ in levels of self-esteem and family functioning as a function of their body fat. Prospectively, physical self-esteem weakly (but significantly) correlated with body fat at ages 1 and 2 yrs, and father's perception of family functioning predicted body fat at age 1 yr only. Results suggested that childhood obesity may not develop as a result of psychosocial factors. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Locally advanced primary colorectal cancer: intraoperative electron and external beam irradiation +/- 5-FU

PURPOSE: For locally advanced primary colorectal cancer, our institution has combined intraoperative electron irradiation (IOERT) with external beam irradiation (EBRT) +/- 5-fluorouracil (5-FU) and surgical resection. Disease control and survival were compared with the current IOERT and prior non-IOERT regimens. METHODS AND MATERIALS: From April 1981 through August 1995, 61 patients received an IOERT dose of 10-20 Gy, usually combined with 45-55 Gy of fractionated EBRT; 56 had minimum follow-up of 18 months. The amount of residual disease remaining at IOERT after exploration and maximal resection in the 56 patients was gross in 16, < or = microscopic in 39, and unresected in 1. RESULTS: Survival (SR) and disease control were analyzed as a function of potential prognostic factors. Factors that achieved statistical significance for improved overall survival included treatment sequence of preop EBRT + 5-FU (vs. postoperative EBRT + 5-FU, p = 0.003) and < or = microscopic residual disease after maximal resection (vs. gross residual, p = 0.005). Those that appeared to favorably impact disease-free survival included EBRT + 5-FU (vs. EBRT alone, p = 0.01), < or = microscopic residual (vs. gross, p = 0.0014), and colon site of primary (vs. rectum, p = 0.009). Failures within an irradiation field have occurred in 4 of 16 patients (25%) who presented with gross residual after partial resection vs. 2 of 39 (5%) with < or = microscopic residual after gross total resection (p = 0.01). The significant prognostic factors for a decrease in distant metastases were the same as for disease-free SR with respective p-values of 0.013 (EBRT + 5-FU), 0.008 (microscopic residual), and 0.03 (colon primary). The current data suggests a relationship between IOERT dose and incidence of Grade 2 or 3 neuropathy (< or = 12.5 Gy--1 of 29 or 3%, > or = 15 Gy--6 of 26 or 23%, p = 0.03). CONCLUSIONS: Both overall survival and disease control appear to be improved with the addition of IOERT to standard treatment. More routine use of systemic therapy is indicated as a component of IOERT containing treatment regimens because the incidence of distant metastases was 50% of patients at risk.     

Individual cognitive-behavioural interventions in early psychosis

BACKGROUND: Cognitive-behavioural treatments have previously been explored in the treatment of chronic psychotic problems, but recently, the effectiveness of these treatments has been investigated with regard to recent onset and acute psychosis. METHOD: The literature relating to cognitive-behavioural treatments in psychosis is explored and the application of the approach to recent onset psychosis is described in detail. RESULTS: There appears to be a growing body of evidence that the advances made in the treatment of people with chronic treatment resistant psychosis can be similarly applied to people with recent onset and acute psychosis. CONCLUSIONS: Cognitive-behavioural treatments are feasible with recent onset psychotic patients although further evaluation of their effectiveness is necessary.