A distributed location system for the active office

Distributed systems for locating people and equipment will be at the heart of tomorrow's active offices. Computer and communications systems continue to proliferate in the office and home. Systems are varied and complex, involving wireless networks and mobile computers. However, systems are underused because the choices of control mechanisms and application interfaces are too diverse. It is therefore pertinent to consider which mechanisms might allow the user to manipulate systems in simple and ubiquitous ways, and how computers can be made more aware of the facilities in their surroundings. Knowledge of the location of people and equipment within an organization is such a mechanism. Annotating a resource database with location information allows location-based heuristics for control and interaction to be constructed. This approach is particularly attractive because location techniques can be devised that are physically unobtrusive and do not rely on explicit user action. The article describes the technology of a system for locating people and equipment, and the design of a distributed system service supporting access to that information. The application interfaces made possible by or that benefit from this facility are presented     

Using simulation‐based experiments for software requirements engineering

We describe the use of simulation‐based experiments to assess the computer support needs of automation supervisors in the United States Postal Service (USPS). Because of the high cost of the proposed system, the inability of supervisors to articulate their computer support needs, and the infeasibility of direct experimentation in the actual work environment, we used a simulation to study end‐user decision making, and to experiment with alternative computer support capabilities. In Phase One we investigated differences between expert and novice information search and decision strategies in the existing work environment. In Phase Two, we tested the impact of computer support features on performance. The empirical results of the two experiments showed how to differentially support experts and novices, and the effectiveness of proposed information systems before they were built. The paper concludes by examining the implications of the project for the software requirements engineering community.     

Direct and GTP-dependent interaction of ADP ribosylation factor 1 with coatomer subunit beta

A site-directed photocrosslink approach was used to elucidate components that interact directly with ADP- ribosylation factor (ARF)-GTP during coat assembly. Two ARF mutants were generated that contain a photolabile amino acid at positions distant to each other within the ARF molecule. Here we show that one of the two positions specifically interacts with coatomer subunit beta both on Golgi membranes and in isolated coat protein complex type I (COPI)-coated vesicles. Thus, a direct and GTP-dependent interaction of coatomer via beta-coat protein complex (COP) with ARF is involved in the coating of COPI-coated vesicles. These data implicate a bivalent interaction of the complex with the donor membrane during vesicle formation.     

Ecclesiastes effects

The reward system in science involves several psychosocial processes that can be named after books in theBible: Merton proposed the Matthew Effect andTurner andChubin offered the Ecclesiastes Hypothesis, based on relevant biblical passages. This article identifies several other bibliometric phenomena described inEcclesiastes, including an explanation of why there is a multiplication of specializations in disciplines with growing literatures.     

Reflected Appraisals, Academic Self-Perceptions, and Math/Science Performance During Early Adolescence.

The authors tested a model of the relations among adolescents' perceptions of parents', teachers', and classmates' support for, valuing of, and beliefs about their competence in math/science; adolescents' own academic self-perceptions concerning math/science; and their academic performance. The sample included 378 middle school students; 65% were Latino, and 21% were European American. Reflected appraisals of adults' beliefs concerning both the importance of and students' competence in math/science, as well as perceived support, predicted students' own self-perceived importance, competence, scholastic behavior, and performance in these courses. Latino students reported lower mean levels of perceived competence than did European American students (controlling for maternal education). Findings have important implications for understanding achievement socialization in ethnically diverse populations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

One-Order-Statistic Conditional Estimators of Shape Parameters of Limited and Pareto Distributions and Scale Parameters of Type II Asymptotic Distributions of Smallest and Largest Values

One-order-statistic estimators are derived for the shape parameter K of the limited distribution function F1(x, ?, K) = 1 - (? - x)K and the Pareto distribution function F2(y, ?, K) = 1 - (y - ?)-K, given the location parameters ? and ?, respectively. Similar estimators are derived for the scale parameters v1 and Vn, of the Type II asymptotic distributions of smallest and largest values, F3(w, v1, K) = 1 - exp[-(w/v1)-K] and F4(z, vn K) = exp [-(z/vn)-K], given the shape parameter K and assuming the location parameter is zero. The one-order-statistic estimators are K?|? = -1/Cmn 1n(? - xmn) for the limited distribution, K?|? = 1/Cmn 1n(ymn - ?) for the Pareto distribution, ?1|K = Cmn-1/K Wmn and ?n|K = Cmn-1/K Zn-m+1,n for the Type II distributions of smallest and largest values, where Xmn, Ymn, Wmn, Zmn are the mth order statistics of samples of size n from the respective distributions and Cmn is the coefficient for a one-order-statistic estimator of the scale parameter of an exponential distribution, which has been tabled in an earlier paper. It is shown that exact confidence bounds can be easily derived for these parameters using exact confidence bounds for the scale parameter of the exponential distribution. Use of the estimators is illustrated by numerical examples.     

Impact of social comparisons on the developing self-perceptions of learning disabled students.

Learning disabled (LD) children's self-perceptions were investigated using the Perceived Competence Scale for Children. This self-report instrument taps children's perceptions of their scholastic and athletic competence, social acceptance, and feelings of global self-worth. Participants in the study were 86 students in Grades 3–8 who attended a public school LD resource room. Results indicated that social comparison processes play an important role in the formation of LD students' perceived academic competence. LD students perceived themselves as becoming less academically competent across the grade span tested when they compared themselves with normally achieving students in their regular classes. When they compared their abilities with LD peers in their resource room, they maintained high perceptions of their own academic competence. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Fate of endogenous steroid hormones in steer feedlots under simulated rainfall-induced runoff

Steroid hormones pose potential risks to fish and other aquatic organisms at extremely low concentrations. To assess the factors affecting the release of endogenous estrogenic and androgenic steroids from feedlots during rainfall, runoff, and soil samples were collected after simulated rainfall on a 14-steer feedlot under different rainfall rates and aging periods and analyzed for six steroid hormones. While only 17α-estradiol, testosterone, and progesterone were detected in fresh manure, 17β-estradiol, estrone, and androstenedione were present in the surficial soil after two weeks. In the feedlot surficial soil, concentrations of 17α-estradiol decreased by approximately 25% accompanied by an equivalent increase in estrone and 17β-estradiol. Aging of the feedlot soils for an additional 7 days had no effect on estrogen and testosterone concentrations, but androstenedione concentrations decreased substantially, and progesterone concentrations increased. Androstenedione and progesterone concentrations in the surficial soil were much higher than could be accounted for by excretion or conversion from testosterone, suggesting that other potential precursors, such as sterols, were converted after excretion. The concentration of androgens and progesterone in the soil were approximately 85% lower after simulated rainfall, but the estrogen concentrations remained approximately constant. The decreased masses could not be accounted for by runoff, suggesting the possibility of rapid microbial transformation upon wetting. All six steroids in the runoff, with the exception of 17β-estradiol, were detected in both the filtered and particle-associated phases at concentrations well above thresholds for biological responses. Runoff from the aged plots contained less 17α-estradiol and testosterone, but more estrone, androstenedione, and progesterone relative to the runoff from the unaged plots, and most of the steroids had a lower particle-associated fraction.     

Use of a gonadotropin-releasing hormone agonist in the evaluation of postmenopausal virilization due to ovarian hyperthecosis. A case report

BACKGROUND: Hyperthecosis in a postmenopausal woman is a very rare cause of virilization, and only five cases have been reported previously. CASE: A woman presented with a nine-year history of increasing hirsutism and a mild virilization beginning in the perimenopausal period. Initial androgen metabolite concentrations suggested attenuated late-onset adrenal hyperplasia, but a trial of dexamethasone treatment was ineffective. Subsequent use of leuprolide acetate resulted in a biochemical and clinical improvement in the signs and symptoms. CONCLUSION: This case is unique because gonadotropin-releasing hormone agonist administration was utilized as both a diagnostic and therapeutic modality.