Radiation risk from screening mammography of women aged 40-49 years

Although direct evidence of carcinogenic risk from mammography is lacking, there is a hypothetical risk from screening because excess breast cancers have been demonstrated in women receiving doses of 0.25-20 Gy. These high-level exposures to the breast occurred from the 1930s to the 1950s due to atomic bomb radiation, multiple chest fluoroscopies, and radiation therapy treatments for benign disease. Using a risk estimate provided by the Biological Effects of Ionizing Radiation (BEIR) V Report of the National Academy of Sciences and a mean breast glandular dose of 4 mGy from a two-view per breast bilateral mammogram, one can estimate that annual mammography of 100,000 women for 10 consecutive years beginning at age 40 will result in at most eight breast cancer deaths during their lifetime. On the other hand, researchers have shown a 24% mortality reduction from biennial screening of women in this age group; this will result in a benefit-to-risk ratio of 48.5 lives saved per life lost and 121.3 years of life saved per year of life lost. An assumed mortality reduction of 36% from annual screening would result in 36.5 lives saved per life lost and 91.3 years of life saved per year of life lost. Thus, the theoretical radiation risk from screening mammography is extremely small compared with the established benefit from this life-saving procedure and should not unduly distract women under age 50 who are considering screening.     

Applying ergonomics to systems: some documented "lessons learned"

Based on evidence accumulated during the author's 45 years of professional experience, the author presents 23 important “lessons learned” regarding applying ergonomics to systems. Documented results from reported cases or other evidence are presented to validate each of these practical learning points.     

Photorefractive Beam splitter for Free-Space Optical Interconnections

A photorefractive beam splitter (PRBS) is introduced as an alternative to a polarizing beam splitter (PBS) for coupling optical power into reflective modulators in a free-space optical interconnection system. The PRBS uses a single diffraction grating recorded in a photorefractive material to redirect the incident laser light into the first diffraction order and onto the modulators. Reflected interconnection light not matching the Bragg angle criteria transmits uncoupled through the beam splitter. Experimental results show that the PRBS provides better, more uniform transmission for off-axis beams than the currently used PBS.     

Similarity-based interference during language comprehension: Evidence from eye tracking during reading.

The nature of working memory operation during complex sentence comprehension was studied by means of eye-tracking methodology. Readers had difficulty when the syntax of a sentence required them to hold 2 similar noun phrases (NPs) in working memory before syntactically and semantically integrating either of the NPs with a verb. In sentence structures that placed these NPs at the same linear distances from one another but allowed integration with a verb for 1 of the NPs, the comprehension difficulty was not seen. These results are interpreted as indicating that similarity-based interference occurs online during the comprehension of complex sentences and that the degree of memory accessibility conventionally associated with different types of NPs does not have a strong effect on sentence processing. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Ergodynamics and macroergonomics in analysis of decision‐making efficiency and complexity

The principles of macroergonomics and the laws of ergodynamics are reviewed. The theories of mutual adaptation and transformation dynamics are presented as a complex basis of the ergodynamics, and they are offered as paradigms for macroergonomic evaluation and design of sociotechnical or human‐machine‐environment decision‐making systems (HMES). Criteria and factors of decision‐making efficiency are studied for different cognitive strategies and their transformations in the course of long‐term training and short‐term decision making in emergencies. Sample system criteria and design guidelines, based on the results of both laboratory studies and actual research and design applications, are provided. A combination of macroergonomics and ergodynamics helps ergonomists to meet rapidly growing requirements of practice and overcome a narrow approach to the workstations analysis when a broader view of complex multilevel system leads to success and instead of traditional static approach the analysis of transformations in technologies, management structures, and work skills is needed.     

A Ducted Fan MAV Anti-torque Control System

The UAVs （unmanned aerial vehicles） exist in various sizes. One of the most interesting niches concerns the UAVs of moderate size （〈 1 m）, also called MAVs （micro air vehicles）. An aerodynamic study of the ULB （Universite Libre de Bruxelles） developed a ducted rotor MAV using the results of full-scale wind tunnel tests that allowed the determination of the platform speed envelope, the power requirements and the endurance characteristics for ISA sea level conditions. Although the ULB MAV appears similar to other ducted-rotor concepts, it fundamentally differs from them as it uses the downwash of a single rotor to compensate the electric motor main rotor torque and to achieve full control around the roll, pitch and yaw axes. This paper explains in detail the components layout of the MAV and the aerodynamic characteristics of the anti-torque blades.     

Misalignment tolerance analysis of free-space optical interconnects via statistical methods

System-level packaging is one of the critical issues that need to be addressed for free space optical interconnections (FSOI) to become useful in desktop systems. The performance of FSOI, e.g., in terms of system bit-error rate, is greatly affected by misalignments in the optical system. Therefore tolerancing, i.e., the ability to analyze and predict the effects of misalignments in the system, is of prime importance to system designers. We introduce an approach in which we study the effects of optical misalignments and other tolerance factors using statistical methods. We use Monte Carlo simulations, design of the experiments, and regression techniques to fit a polynomial equation that expresses the relationship between the system performance and the tolerance factors. This prediction model can be used for design, cost optimization, and quality control purposes. In addition, we perform a sensitivity analysis to determine those tolerance variables that have the greatest effect on system performance.     

Immunolocalization of transforming growth factor-beta 1 and transforming growth factor-beta 2 in the mouse ovary during gonadotrophin-induced follicular maturation

An immunohistochemical approach was utilized to evaluate the cellular distribution of transforming growth factor-beta 1 (TGF beta 1) and transforming growth factor beta 2 (TGF beta 2) at different stages of follicle development in the prepubertal mouse ovary under the following conditions: (i) after pregnant mare's serum gonadotrophin (PMSG) treatment; (ii) after PMSG and human chorionic gonadotrophin (HCG) treatment; (iii) after PMSG and HCG treatment plus mating. In the immature ovary, TGF beta 1 and TGF beta 2 immunoreactivities are localized in theca and granulosa cells and in oocytes. After PMSG treatment, TGF beta 1 and TGF beta 2 immunoreactivities are localized in granulosa cells; in addition, TGF beta 2 staining is noted in the matrix surrounding antral cells. Staining for both TGR beta 1 and TGF beta 2 drops in the theca but persists in the oocyte. PMSG plus HCG treatment results in a significant increase in TGF beta 1 and TGF beta 2 immunoreactivity in the theca and in the maintenance of TGF beta 1 staining in both basal granulosa cells and cumulus cells whereas TGF beta 2 immunoreactivity is essentially localized in the matrix surrounding cumulus cells. Staining for TGF beta 1 and TGF beta 2 persists in the oocyte. Following PMSG plus HCG treatment and mating, TGF beta 1 immunoreactivity is localized in the luteal cells of corpora lutea and TGF beta 2 shows a similar localization pattern. This study provides evidence that TGF beta 1 and TGF beta 2 peptides are expressed in specific cell types during induced follicular maturation in the mouse ovary.     

Determining the cost-benefits of ergonomics projects and factors that lead to their success

Managers usually can justify financially supporting a proposed ergonomics project only when it is supported by a sound cost-benefit analysis. The factors to consider and sources of information for calculating the costs and benefits of proposed ergonomic projects are described. Based upon his experience and review of numerous ergonomics projects, the common characteristics of successful ergonomics interventions gleaned by the author are described and then illustrated by actual documented cases.     

A theory and method of love.

Previous work by the authors and colleagues (1984) extended J. A. Lee's (1973/1976) theory of 6 basic love styles: eros (passionate love); ludus (game-playing love); storge (friendship love); pragma (logical, "shopping list" love); mania (possessive, dependent love); and agape (all-giving, selfless love). In Study 1, 807 undergraduates completed a 42-item rating questionnaire, with 7 items measuring each of the love styles. Six love style scales emerged clearly from factor analysis. Internal reliability was shown for each scale, and the scales had low intercorrelations with each other. Significant relationships were found between love attitudes and several background variables, including gender, ethnicity, previous love experiences, current love status, and self-esteem. Study 2, with 567 Ss, replicated the factor structure, factor loadings, and reliability analyses of the 1st study. The significant relationships between love attitudes and gender, previous love experiences, current love status, and self-esteem were also consistent with the results of Study 1. (30 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)