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排序方式: 共有46条查询结果,搜索用时 265 毫秒
1.
Natalia Ziemkiewicz Genevieve Hilliard Nicholas A. Pullen Koyal Garg 《International journal of molecular sciences》2021,22(6)
Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide variety of innate and adaptive immune cells orchestrate the complex process of muscle repair. This review provides information about the various types of immune cells and biomolecules that have been shown to mediate muscle regeneration following injury and degenerative diseases. Recently developed cell and drug-based immunomodulatory strategies are highlighted. An improved understanding of the immune response to injured and diseased skeletal muscle will be essential for the development of therapeutic strategies. 相似文献
2.
The purpose of this study was to analyse the adoption of crisis preparedness measures by meeting planners. The study sought to determine how the adoption of crisis preparedness measures relates to meeting planner characteristics and identify the elements that influence their adoption (or lack of adoption) of these measures. A survey of professional meeting planners identified significant differences in the frequency of use of some key core crisis preparedness measures. Additionally, 10 categories of elements influencing the adoption of or failure to adopt crisis preparedness measures were identified. The findings of this study should be of interest to meeting organizers and professionals who want to make their meetings more crisis prepared rather than crisis prone. 相似文献
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RB Hays L McKusick L Pollack R Hilliard C Hoff TJ Coates 《Canadian Metallurgical Quarterly》1993,7(3):425-431
OBJECTIVES: To examine gay men's patterns of self-disclosure of HIV seropositivity to friends, lovers, relatives and colleagues; to assess the effects of disclosure; and to identify reasons for not disclosing to particular individuals. DESIGN: Longitudinal questionnaire survey of gay men. METHODS: A total of 163 HIV-positive men participating in the AIDS Behavioral Research Project, a longitudinal study of San Francisco gay men, completed questionnaires about their self-disclosure patterns, health status, and psychological well-being. RESULTS: HIV-positive men were most likely to disclose their status to lovers and closest gay friends. Asymptomatic men were less likely to disclose to relatives and colleagues than symptomatic men. Friends and lovers were rated as responding more helpfully than relatives and colleagues. Men who perceived their significant others as responding more helpfully were less depressed and anxious currently and 1 year later. A variety of reasons were given for not disclosing, including not wanting to worry others, fear of discrimination, fear of disrupting relationships, and emotional self-protection. CONCLUSION: While disclosure can have advantages for both HIV-positive individuals and their significant others, HIV-positive individuals must be assured that the benefits of doing so will outweigh the potential costs. 相似文献
6.
A technique is described for preparing compositionally modulated PbTe/Bi films on mica with a well-defined [111] epitaxy by evaporation. For short wavelengths or a large ratio of PbTe to bismuth, the bismuth layers of the film approached a quasi-simple-cubic structure. 相似文献
7.
Superconducting properties of V/Fe superlattices 总被引:1,自引:0,他引:1
H. K. Wong B. Y. Jin H. Q. Yang J. B. Ketterson J. E. Hilliard 《Journal of Low Temperature Physics》1986,63(3-4):307-315
Measurements are reported on the superconducting properties of V/Fe superlatitices showing the interplay between ferromagnetism and superconductivity. When the V layer thickness is on the order of the BCS coherence length and the Fe layer is only a few atomic planes thick, a 2D–3D crossover is observed in the temperature dependence of the parallel upper critical field Hc2. This implies the coexistence of superconductivity and ferromagnetism in the Fe layers. Three-dimensional behavior for thinner Fe layers is observed (1 atomic plane) and 2D behavior for thicker Fe layers (>10 atomic planes).On leave from the Institute of Physics, Academia Sinica, Beijing, China. 相似文献
8.
Tyvette S. Hilliard Brooke Kowalski Kyle Iwamoto Elizabeth A. Agadi Yueying Liu Jing Yang Marwa Asem Yuliya Klymenko Jeff Johnson Zonggao Shi Gifty Marfowaa Madeleine G. Yemc Phillip Petrasko M. Sharon Stack 《International journal of molecular sciences》2021,22(22)
Mesothelin (MSLN), a glycoprotein normally expressed by mesothelial cells, is overexpressed in ovarian cancer (OvCa) suggesting a role in tumor progression, although the biological function is not fully understood. OvCa has a high mortality rate due to diagnosis at advanced stage disease with intraperitoneal metastasis. Tumor cells detach from the primary tumor as single cells or multicellular aggregates (MCAs) and attach to the mesothelium of organs within the peritoneal cavity producing widely disseminated secondary lesions. To investigate the role of host MSLN in the peritoneal cavity we used a mouse model with a null mutation in the MSLN gene (MSLNKO). The deletion of host MSLN expression modified the peritoneal ultrastructure resulting in abnormal mesothelial cell surface architecture and altered omental collagen fibril organization. Co-culture of murine OvCa cells with primary mesothelial cells regardless of MSLN expression formed compact MCAs. However, co-culture with MSLNKO mesothelial cells resulted in smaller MCAs. An allograft tumor study, using wild-type mice (MSLNWT) or MSLNKO mice injected intraperitoneally with murine OvCa cells demonstrated a significant decrease in peritoneal metastatic tumor burden in MSLNKO mice compared to MSLNWT mice. Together, these data support a role for host MSLN in the progression of OvCa metastasis. 相似文献
9.
The nearest-neighbour distance distribution was used as a criterion to investigate the dispersion of triple junctions. Comparison of the expected and measured distributions by the χ2-test indicated that the triple junctions were probably not randomly located, contrary to an earlier conclusion based on an areal probe of the same specimen. The present results suggest that areal probes are insensitive to large deviations from randomness in the location of points in a plane. 相似文献
10.
David Katz Wei Shi Marty Wildes Julia K. Hilliard 《Journal of The Association for Laboratory Automation》2002,7(6):108-113
A robot-assisted automated facility was established within a biosafety level 3 laboratory located on a university campus. A unique integration of a Genesis (TECAN) liquid handler into the SAGIAN Core System (Beckman-Coulter) enabled tube liquid handling and transfer of reagents from tubes to microplates. An automated enzyme immunoassay (ELISA) for detecting herpes B virus antibodies was developed. Repetition experiments of the automated ELISA and comparison to the manual ELISA demonstrated the efficacy and high reproducibility of the automated method. It is anticipated that research and education activities will benefit from the establishment of the automated diagnostic laboratory in an academic environment. 相似文献