全文获取类型
收费全文 | 1018篇 |
免费 | 10篇 |
专业分类
电工技术 | 19篇 |
化学工业 | 84篇 |
金属工艺 | 3篇 |
机械仪表 | 2篇 |
建筑科学 | 15篇 |
矿业工程 | 4篇 |
能源动力 | 1篇 |
轻工业 | 196篇 |
水利工程 | 12篇 |
无线电 | 35篇 |
一般工业技术 | 47篇 |
冶金工业 | 574篇 |
原子能技术 | 1篇 |
自动化技术 | 35篇 |
出版年
2023年 | 6篇 |
2022年 | 6篇 |
2019年 | 10篇 |
2018年 | 6篇 |
2017年 | 6篇 |
2016年 | 6篇 |
2014年 | 9篇 |
2013年 | 12篇 |
2012年 | 10篇 |
2011年 | 11篇 |
2010年 | 10篇 |
2009年 | 10篇 |
2008年 | 11篇 |
2007年 | 13篇 |
2006年 | 13篇 |
2005年 | 16篇 |
2004年 | 11篇 |
2003年 | 14篇 |
2002年 | 11篇 |
2001年 | 13篇 |
2000年 | 6篇 |
1999年 | 19篇 |
1998年 | 188篇 |
1997年 | 132篇 |
1996年 | 72篇 |
1995年 | 43篇 |
1994年 | 29篇 |
1993年 | 37篇 |
1992年 | 11篇 |
1991年 | 9篇 |
1990年 | 15篇 |
1989年 | 12篇 |
1988年 | 13篇 |
1987年 | 8篇 |
1986年 | 21篇 |
1985年 | 21篇 |
1984年 | 10篇 |
1983年 | 5篇 |
1982年 | 10篇 |
1981年 | 12篇 |
1980年 | 12篇 |
1979年 | 4篇 |
1978年 | 6篇 |
1977年 | 15篇 |
1976年 | 43篇 |
1975年 | 11篇 |
1974年 | 10篇 |
1973年 | 10篇 |
1972年 | 8篇 |
1968年 | 4篇 |
排序方式: 共有1028条查询结果,搜索用时 15 毫秒
1.
2.
IR.A.A.P. Schudelaro 《Information & Communications Technology Law》2003,12(1):49-55
The European Electronic Money Directive contains a definition of electronic money. However, determining which systems involving the use of electronic value fall under its scope can be more complicated than one might think. This issue is explored in this article through consideration of the question of whether prepaid mobile phone credits qualify as electronic money—a question that is currently being debated by telecommunications operators and regulators. 相似文献
3.
F Lista V Bertness CJ Guidos JS Danska IR Kirsch 《Canadian Metallurgical Quarterly》1997,57(19):4408-4413
Pilot studies in human populations have demonstrated a correlation between the level of antigen receptor trans-rearrangements and risk (at the population level) of lymphoid malignancy. Irradiation of newborn severe combined immune deficiency mice results in an increased risk of subsequent development of thymic lymphoma (100% of mice so irradiated are dead of thymic lymphoma by 20 weeks of age). We, therefore, assayed the occurrence of trans-rearrangements in this well-controlled mouse mutant system and found a 50-100-fold increase in the absolute number of TCRGV-TCRBJ trans-rearrangements compared to unirradiated littermates (and a comparable fold increase over age-matched BALB/c mice) at 2 weeks following irradiation. We also found a marked disproportion in generating trans-rearrangements versus intralocus rearrangements in the severe combined immune deficiency system compared to BALB/c, independent of irradiation. The trans-rearrangements noted were polyclonal in nature. These data, again, suggest that the absolute level of antigen receptor trans-rearrangements may serve as a biomarker of lymphoma risk. 相似文献
4.
A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides 总被引:1,自引:0,他引:1
FE Di Padova H Brade GR Barclay IR Poxton E Liehl E Schuetze HP Kocher G Ramsay MH Schreier DB McClelland 《Canadian Metallurgical Quarterly》1993,61(9):3863-3872
During the last decade, episodes of sepsis have increased and Escherichia coli has remained the most frequent clinical isolate. Lipopolysaccharides (LPS; endotoxin) are the major toxic and antigenic components of gram-negative bacteria and qualify as targets for therapeutic interventions. Molecules that neutralize the toxic effects of LPS are actively investigated. In this paper, we describe a murine monoclonal antibody (MAb; WN1 222-5), broadly cross-reactive and cross-protective for smooth (S)-form and rough (R)-form LPS. As shown in enzyme-linked immunosorbent assay and the passive hemolysis assay, WN1 222-5 binds to the five known E. coli core chemotypes, to Salmonella core, and to S-form LPS having these core structures. In immunoblots, it is shown to react with both the nonsubstituted core LPS and with LPS carrying O-side chains, indicating the exposure of the epitope in both S-form and R-form LPS. This MAb of the immunoglobulin G2a class is not lipid A reactive but binds to E. coli J5, an RcP+ mutant which carries an inner core structure common to many members of the family Enterobacteriaceae. Phosphate groups present in the inner core contribute to the epitope but are not essential for the binding of WN1 222-5 to complete core LPS. Cross-reactivity for clinical bacterial isolates is broad. WN1 222-5 binds to all E. coli clinical isolates tested so far (79 blood isolates, 80 urinary isolates, and 21 fecal isolates) and to some Citrobacter, Enterobacter, and Klebsiella isolates. This pattern of reactivity indicates that its binding epitope is widespread among members of the Enterobacteriaceae. WN1 222-5 exhibits biologically relevant activities. In vitro, it inhibits the Limulus amoebocyte lysate assay activity of S-form and R-form LPS in a dose-dependent manner and it neutralizes the LPS-induced release of clinically relevant monokines (interleukin 6 and tumor necrosis factor). In vivo, WN1 222-5 blocks endotoxin-induced pyrogenicity in rabbits and lethality in galactosamine-sensitized mice. The discovery of WN1 222-5 settles the long-lasting controversy over the existence of anti-core LPS MAbs with both cross-reactive and cross-protective activity, opening new possibilities for the immunotherapy of sepsis caused by gram-negative bacteria. 相似文献
5.
M Jarman HM Coley IR Judson TJ Thornton DE Wilman G Abel CJ Rutty 《Canadian Metallurgical Quarterly》1993,36(26):4195-4200
In exploring the structural features which determine the antitumor activity of 2,4,6-tris-[(hydroxymethyl)methylamino]-1,3,5-triazine (trimelamol, 1), we have synthesized analogues in which the methyl groups have been replaced by the electron-withdrawing substituents 2,2,2-trifluoroethyl (5), propargyl (13), and cyanomethyl (15) via the respective tris(alkylamino)triazines 3, 12, and 14. Three mono[(hydroxymethyl)amino]triazines (4, 7, and 10) were also prepared. All the new tris(hydroxymethyl) derivatives showed cytotoxicities toward a variety of experimental rodent and human ovarian tumor cell lines similar to those shown by 1, the cyanomethyl analogue (15) having the most favorable profile. Mono(hydroxymethyl) derivatives (4 and 7) were ca. one-third as toxic. The new tris(hydroxymethyl) analogues were more stable to aqueous hydrolysis than was 1. Half-life (pH 7.5) values were, for 1, 120 min, for 5, 690 min, for 13, 450 min, and for 15, 275 min, but at pH 2.0, 15 (t1/2 350 min) was the most stable. This cyanomethyl analogue was also the most water-soluble, being comparable to 1 whereas 5 and 13 were poorly soluble. 相似文献
6.
7.
42 different plywoods consisting of a maximum number of 9 beechveneers were investigated. This report describes the relations between the composition of the panels and the impact bending behavior. Recommandations are given for the manufacture of plywood with a high shock resistance. 相似文献
8.
9.
A novel method for the computation of the steady state of nonlinear oscillators including distributed elements is presented which exploits advantages of both time-domain and frequency-domain simulation. The oscillator network is divided into a linear subnetwork described by a hybrid matrix in the frequency domain and a nonlinear differential equation solved in the time domain. The periodic steady state of the oscillator is shown to be equivalent to the solution of a boundary value problem, where the boundary conditions are given at a set of points along the time axis. For the solution of the boundary value problem the multiple shooting algorithm is applied. It is shown that the bandwidth in the nonlinear subnetwork can be chosen arbitrarily high regardless of the number of harmonics at the ports connecting the subnetworks. In order to demonstrate the feasibility of the method and to discuss the error mechanisms it is applied to two examples: a Clapp oscillator including a piecewise-linear characteristic and an integrated GaAs MESFET oscillator at 10.7 GHz 相似文献
10.
H King MC McCulloch JA Barrie E Kyriakides CV Beechey BM Cattanach IR Griffiths 《Canadian Metallurgical Quarterly》1997,26(8):557-566
Animals with spontaneous mutations affecting myelin formation have provided useful information about the genetic and cellular mechanisms regulating normal and abnormal myelination. In this paper we describe a novel murine mutation termed hindshaker (hsh), which is inherited in an autosomal recessive manner. Affected mice are characterised by a variable tremor of the hind end which commences at about 2 weeks of age and largely disappears in animals older than 6 weeks. There is hypomyelination affecting predominantly the spinal cord, although the optic nerves and brain are involved to a much lesser degree. The defect of thinly myelinated and naked axons is maximal at 20 days of age and largely resolves with time so that in the adult most axons are myelinated. The myelin structure appears normal and immunostains for the major proteins. Although the distribution of oligodendrocytes in the spinal cord is similar to normal during the period of hypomyelination, there are fewer mature cells. The hsh mutation appears to delay the maturation of oligodendrocytes, particularly in the spinal cord. Additionally, there is a considerable variation in phenotypic expression and in penetrance when the mutation is expressed on different genetic backgrounds, suggesting the hsh locus is subject to the influence of modifying gene(s). Identification of the hsh gene should identify a factor important in the development of oligodendrocytes, particularly those in the spinal cord. 相似文献