Retrospective evaluation of blood immunologic parameters in the course of remission of acute lymphoblastic leukemia in children

The present study concerns 63 patients with autosomal polycystic kidney disease. In 35 patients the disease was linked to chromosome 16, and in the remaining 28 it was not linked to this chromosome. A comparative clinical analysis of the clinical manifestations of each of the forms was carried out using the objective criteria of age at onset of the initial clinical manifestations of ADPKD, age at onset of the hypertension syndrome, age at onset of the initial chronic renal failure and beginning of haemodialysis. The results show that the clinical manifestations of ADPKD in the patients with the unlinked from are milder and with a better prognosis.     

Biochemical evaluation of the therapeutic effectiveness of coccidin in coccidiosis of hens

20-day old chicks were infected with Eimeria tenella, treated with coccidin (250 mg/kg) and free amino acids of the femoral muscle tissues were studied. The infection of chicks was accompanied with metabolism disorders of all amino acids of the muscle tissue excluding leucine, methionine, tyrosine and phenylalanine. During the treatment of infected chicks with coccidin the level of free amino acids re-established within 10 days. This preparation affected most of all metabolism of alanine, isoleucine, aspartic acid and glycine and was less efficient in the re-establishment of the level araginine, lysine and threonine. It is suggested during the tests of coccidiostatics to take into consideration free amino acids of muscle tissues for the estimation of the efficiency of medical substances.