Functional results of surgical repair of chronic duodenal insufficiency associated with duodenal ulcer

The results of 312 patients examination in late follow-up period after conduction of the organ preserving intervention, gastric resection and reconstructive operation with chronic duodenal insufficiency correction, concurrent with duodenal ulcer, its acute complications, postvagotomy and postresection syndrome are adduced. An excellent and good result was noted in 70.2% of patients, fair--in 23.4%, bad--in 6.4%.     

The changes of serum cortisol and aldosterone in patients with cancer of vestibular section of larynx after irradiation and with and without surgery

Enzyme immunoassay was used to measure serum levels of hydrocortisone and aldosterone in 85 patients with vestibular laryngeal cancer before treatment and after it. The treatment consisted of either radiation alone or radiation followed by surgery. Pretreatment examination revealed adrenal dysfunction evident from enhanced glucocorticoid and inhibited mineral corticoid activity. Radiotherapy alone or in combination with surgery gave rise to a trend to a decline in glucocorticoid activity and stimulated mineral corticoid activity.     

Surgical treatment of duodenal ulcer with chronic duodenal obstruction

Follow-up treatment results of 892 patients with duodenal ulcer (DU) are presented and the choice of surgical policy in its combination with chronic duodenal obstruction (CDO) in 307 (34.4%) patients is substantiated. Depending on peculiarities of DU, the kind and the stage of CDO, organ saving (140) or stomach resection (167) in combination with correction CDO interventions (287) were carried out. The course of the postoperative period was characterised by basic morphofunctional changes and by achievement of completeness of duodenal passage. Intermittent motor-evacuatory disorders were observed in 55 (17.9%) patients. Lethal outcome was in 1 case. Long-term functional results of the operations were studied in 267 patients. Excellent and good results were obtained in 66.3%, favorable-in 32.24% and unfavorable-in 1.44% of patients. The dependence of immediate and remote results of the operations on the effectiveness of the correction of associated CDO was established.     

Endoscopic diagnosis of chronic obstruction of the duodenum in association with peptic ulcer

The results of gut endoscopic examination in 460 patients with duodenal ulcer disease concurrent with its chronic obstruction (CI) are adduced. Direct and indirect endoscopic signs of duodenal CI are revealed in 399 (86.73%) of patients. Endoscopic criteria of the CI stage determination are described: duodenal stenosis, pyloric sphincter deformity and insufficiency, reflux-gastritis and the gastrostasis signs while satisfactory pyloric passability.