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排序方式: 共有192条查询结果,搜索用时 46 毫秒
1.
Jon T. Carter Paul E. Krajewski Ravi Verma 《JOM Journal of the Minerals, Metals and Materials Society》2008,60(11):77-81
The hot blow forming of magnesium sheet offers significant opportunity for forming complex, lightweight parts for automotive
applications. This paper characterizes the elevated-temperature formability of AZ31 magnesium sheet materials and the effect
of processing conditions on the performance of these materials. In addition, magnesium sheet application development at General
Motors Corporation is reviewed. 相似文献
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In the present work it was directly demonstrated that increased acetylation level of histones causes the decompactization of 30 nm chromatin fiber, as revealed by low-percentage agarose gel electrophoresis. In the light of obtained results the possible molecular mechanism of the decompactization of acetylated fiber is discussed. 相似文献
4.
Apoptosis in the failing human heart 总被引:1,自引:0,他引:1
G Olivetti R Abbi F Quaini J Kajstura W Cheng JA Nitahara E Quaini C Di Loreto CA Beltrami S Krajewski JC Reed P Anversa 《Canadian Metallurgical Quarterly》1997,336(16):1131-1141
BACKGROUND: Loss of myocytes is an important mechanism in the development of cardiac failure of either ischemic or nonischemic origin. However, whether programmed cell death (apoptosis) is implicated in the terminal stages of heart failure is not known. We therefore studied the magnitude of myocyte apoptosis in patients with intractable congestive heart failure. METHODS: Myocardial samples were obtained from the hearts of 36 patients who underwent cardiac transplantation and from the hearts of 3 patients who died soon after myocardial infarction. Samples from 11 normal hearts were used as controls. Apoptosis was evaluated histochemically, biochemically, and by a combination of histochemical analysis and confocal microscopy. The expression of two proto-oncogenes that influence apoptosis, BCL2 and BAX, was also determined. RESULTS: Heart failure was characterized morphologically by a 232-fold increase in myocyte apoptosis and biochemically by DNA laddering (an indicator of apoptosis). The histochemical demonstration of DNA-strand breaks in myocyte nuclei was coupled with the documentation of chromatin condensation and fragmentation by confocal microscopy. All these findings reflect apoptosis of myocytes. The percentage of myocytes labeled with BCL2 (which protects cells against apoptosis) was 1.8 times as high in the hearts of patients with cardiac failure as in the normal hearts, whereas labeling with BAX (which promotes apoptosis) remained constant. The near doubling of the expression of BCL2 in the cardiac tissue of patients with heart failure was confirmed by Western blotting. CONCLUSIONS: Programmed death of myocytes occurs in the decompensated human heart in spite of the enhanced expression of BCL2; this phenomenon may contribute to the progression of cardiac dysfunction. 相似文献
5.
Optical studies of LiKSO4 crystals were performed in polarized 11yh.t within the temperature range from 300 up to 1000 K. The observations confirmed the existence of two phase transitions at about 700 and 940 K respectively. The high-temperature phase between 700 and 940 K was found to be ferroelastic. 相似文献
6.
A. Krajewski A. Ravaglioli B. Fabbri C. B. Azzoni 《Journal of Materials Science》1987,22(4):1228-1234
The adhesion between bioactive glass and metal is improved by the addition of small amounts of transition ion oxides. Because it is difficult to carry outin vivo tests to check with continuity, chemical information about the interactions of the different doped glasses with living tissues, the behaviour of the different doped bioactive glasses in a liquid simulating physiological conditions was studied. Chemical and EPR analyses show that the mineralization phenomena around the bioglasses in the tissues also take place at an inorganic level. This simulation shows that the ions released from the different vitreous systems are correlated with the adopted doping. In particular an increase in doping with iron involves a decrease in the release rate of the other ions. Furthermore the doping agents allow a control of the release rate and consequently the obtainment of the best biological adaptability. 相似文献
7.
Gianmarco de Felice Maria Antonietta Aiello Carmelo Caggegi Francesca Ceroni Stefano De Santis Enrico Garbin Natalino Gattesco Łukasz Hojdys Piotr Krajewski Arkadiusz Kwiecień Marianovella Leone Gian Piero Lignola Claudio Mazzotti Daniel Oliveira Corina Papanicolaou Carlo Poggi Thanasis Triantafillou Maria Rosa Valluzzi Alberto Viskovic 《Materials and Structures》2018,51(4):95
Textile Reinforced Mortar (TRM), also known as Fabric Reinforced Mortar or Fabric Reinforced Cementitious Matrix, composites are an emerging technology for the external repair and strengthening of existing structures. For most applications, the effectiveness of the TRM reinforcement relies on its bond performance. This recommendation identifies the best practice to characterize the bond behaviour of TRM. A shear bond test method is proposed to determine the peak axial stress (associated with the maximum load that can be transferred from the structural member to the externally bonded TRM reinforcement), the stress–slip relationship and the failure mode that controls the TRM-to-substrate load transfer capacity. Guidelines on specimen manufacturing, experimental setup, test execution, and determination of test results are provided. 相似文献
8.
This study examined whether gender and work stressor context interacted to affect reports of occupational coping strategies. Participants (N=113) were asked to indicate how they would cope with both self-focused (i.e., solitary) and interpersonal (i.e., group) work overload contexts by providing responses to the Cybernetic Coping Scale (J. Edwards & A. J. Baglioni, 1993). Consistent with the hypothesized interaction, male and female participants evidenced similar coping strategies in the self-focused work overload context, whereas female participants showed significantly higher use of coping (T2=.08, p 相似文献
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