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排序方式: 共有2182条查询结果,搜索用时 15 毫秒
1.
GN Mozhokina GB Sokolova OV Makarova LP Mikha?lova 《Canadian Metallurgical Quarterly》1996,41(7-8):31-33
The effect of lomefloxacin was studied on mice with experimental infection due to Mycobacterium tuberculosis. The antibiotic was administered in doses of 100 and 200 mg/kg. It was shown that the use of lomefloxacin for a month provided a lower death rate of the animals with progressing acute generalized tuberculosis, a lower level of the lesions in the internal organs and a lower number of the Mycobacterium isolates from them. The efficacy of the treatment depended on the drug dose. When lomefloxacin was used in a dose of 200 mg/kg, the survival rate was much higher and the number of the epithelial unicellular granulomas in the tissue of the lung and spleen was markedly decreased while with the lower dose the indices did not differ from those in the control. 相似文献
2.
DC Reynolds CE Leak KK Bajaj CE Stutz RL Jones KR Evans PW Yu WM Theis 《Canadian Metallurgical Quarterly》1989,40(9):6210-6217
3.
Cypriano G da Trindade Neto Ana LP Fernandes Ana IB Santos Waldenice A Morais Marcos VM Navarro Tereza NC Dantas Mrcia R Pereira Jos LC Fonseca 《Polymer International》2005,54(4):659-666
Complexation of chitosan in aqueous solutions by low molecular weight electrolytes is one of the simplest methods for the preparation of aqueous chitosan dispersions. In this work, the influence of storage time, sulfate concentration, method of preparation and surfactant content on some properties of the resultant chitosan dispersions (turbidity, viscosity and zeta potential) was analyzed. Turbidimetry was adequate to monitor the formation of particles, while viscometry was suitable to monitor changes in the dispersing phase. An analysis of the properties of these systems, mainly in terms of particle–particle and macromolecule–macromolecule interactions was carried out. Copyright © 2004 Society of Chemical Industry 相似文献
4.
The atomistic structure and energies of high-index interphase boundaries are explored using a combination of molecular statics
and dynamics simulations with embedded atom potentials. We investigate planar boundaries between the α2 and γ phases in the Ti−Al system. The class of boundaries considered has a high-index boundary orientation; the orientation
relationship between the α2 and γ phases also is high index, and a set of planes from each phase meet edge to edge at the boundary plane. For the particular
case of a boundary that is commensurate in one direction and coincides with a moiré plane given by the so-called “Δg” diffraction condition, the boundary is not structurally singular, but it is energetically stable and does not appear to
dissociate into other low-energy configurations. Misfit compensating defects are not observed; misfit in directions other
than the commensurate one appears to be distributed uniformly. The boundary energy is evaluated as a function of the orientation
of the boundary plane, and the edge-to-edge (moiré) boundary is found to lie in an energy cusp.
This article is based on a presentation made in the “Hume-Rothery Symposium on Structure and Diffusional Growth Mechanisms
of Irrational Interphase Boundaries,” which occurred during the TMS Winter meeting, March 15–17, 2004, in Charlotte, NC, under
the auspices of the TMS Alloy Phases Committee and the co-sponsorship of the TMS-ASM Phase Transformations Committee. 相似文献
5.
The goal of the PMS project is to produce an environment in which the intelligent online assessment of the design for large-scale ADA programming projects is provided. The focus is on the representation of knowledge about the design process for an individual module. Changes in pseudocode complexity are measured in terms of partial metrics. These metrics can take the designers inferences about the pseudocode program structure into account when assessing module complexity. Next, a model of the stepwise refinement process is given which demonstrates how pseudocode elaboration decisions can be modelled in partial metric terms. Finally, the decisions associated with each refinement step for 17 example refinements taken from the computer science literature are described using partial metrics. 相似文献
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M Fornerod J van Deursen S van Baal A Reynolds D Davis KG Murti J Fransen G Grosveld 《Canadian Metallurgical Quarterly》1997,16(4):807-816
The oncogenic nucleoporin CAN/Nup214 is essential in vertebrate cells. Its depletion results in defective nuclear protein import, inhibition of messenger RNA export and cell cycle arrest. We recently found that CAN associates with proteins of 88 and 112 kDa, which we have now cloned and characterized. The 88 kDa protein is a novel nuclear pore complex (NPC) component, which we have named Nup88. Depletion of CAN from the NPC results in concomitant loss of Nup88, indicating that the localization of Nup88 to the NPC is dependent on CAN binding. The 112 kDa protein is the human homologue of yeast CRM1, a protein known to be required for maintenance of correct chromosome structure. This human CRM1 (hCRM1) localized to the NPC as well as to the nucleoplasm. Nuclear overexpression of the FG-repeat region of CAN, containing its hCRM1-interaction domain, resulted in depletion of hCRM1 from the NPC. In CAN-/- mouse embryos lacking CAN, hCRM1 remained in the nuclear envelope, suggesting that this protein can also bind to other repeat-containing nucleoporins. Lastly, hCRM1 shares a domain of significant homology with importin-beta, a cytoplasmic transport factor that interacts with nucleoporin repeat regions. We propose that hCRM1 is a soluble nuclear transport factor that interacts with the NPC. 相似文献
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