排序方式: 共有26条查询结果,搜索用时 31 毫秒
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IuM Ovchinnikov MIa Bezchinskaia VV Novitski? DM Mashtakov 《Canadian Metallurgical Quarterly》1996,(3):44-45
A novel technique of surgical treatment of chronic tonsillitis is presented. It implies the use of Ne-YAG laser in contract regimen. Good results were obtained in experiments on the exposure of distal tonsils to intralacunar laser radiation. 相似文献
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MIa Otter 《Canadian Metallurgical Quarterly》1997,(6):37-40
Hypoxitherapy proposed by Russian researchers promotes a 2-3-fold decrease in morbidity of poor-health subjects (high risk groups). As shown by the experience gained in the medical department of the Moskvich car corporation hypoxitherapy provides enhancement of the human resistance to extreme ecological conditions responsible for high mortality of population in the Russian Federation. The information on the production of special devices, hypoxicators, for creation of hypoxic mixtures (mountain air) is given. Large-scale application of hypoxitherapy for prevention, treatment and rehabilitation seems most effective in the conditions of sanatoria. 相似文献
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RG Glushkov SP Golitsyn EV Dorodnikova EB Ma?kov MD Mashkovski? IN Merkulova LV Rozenshtraukh MIa Ruda SIa Skachilova EI Chazov SD Iuzhakov 《Canadian Metallurgical Quarterly》1998,(11):38-41
The paper presents experimental and clinical findings of the new antiarrhythmic drug nibentan. The agent was found to be a class-III antiarrhythmic agent in terms of its electrophysiological effects and an inhibitor of the delayed rectifier potassium current in terms of its effects on the ionic channels of cardiomyocytes. The clinical trial of nibentan shows that the drug is highly effective (in 70-100% of cases) in patients with atrial flutter and fibrillation and in those with supraventricular tachycardia and it is less effective in suppressing ventricular premature contractions and tachycardia. The rate of arrhythmogenic effects produced by the drug was inversely related to its antiarrhythmic action. Nibentan has been approved for clinical use. 相似文献
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EIu Kolbanovskaia AL Okorokov KI Panov KM Poliakov RW Hartley MIa Karpe?ski? 《Canadian Metallurgical Quarterly》1994,28(3):602-609
Barnase, an extracellular ribonuclease produced by Bacillus amyloliquefaciens, belongs to a family of small microbial ribonucleases with similar structure and properties. These enzymes hydrolyze phosphodiester bonds on the 3' side of guanosine nucleotides in RNA. The guanylic specificity of barnase is more pronounced in the hydrolysis of dinucleotides or cyclonucleotide phosphates as substrates than in the hydrolysis of RNA or polynucleotides. To have an insight into the molecular basis of this phenomenon, we mutated amino acid residue Ser-57 in the "base recognition loop" of RNase Ba. The mutant protein was expressed in Escherichia coli producing system and purified for the study of the kinetic properties in the cleavage polynucleotide reactions. It was shown that the mutation of amino acid residue Ser-57 for Ala in the "recognition loop" of RNase Ba does not significantly influence the kinetic parametres of hydrolysis of polynucleotide substrates. 相似文献
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