600 A IGBT开关电路及其散热系统设计

采用IGBT开关电路，对大功率电阻带进行直流脉宽调制控制，实现了内燃机车大功率直流发电机负载实验中的负载大小的连续调节。为了避免在实验过程中IGBT器件的温度过高，采用独特的双管IGBT结构和双向强迫风冷的散热系统。实验表明该电路运行稳定、可靠。     

Financial strain, received support, anticipated support, and depressive symptoms in the People's Republic of China.

The purpose of this study is to examine the interface between financial strain, informal received economic support, informal anticipated financial support, and psychological distress in later life. Data provided by a large probability sample of older adults in the People's Republic of China reveal that the relationship between financial difficulty and psychological distress is stronger for older adults who receive more economic assistance. However, the results involving anticipated support are in the opposite direction. More specifically, the association between financial problems and psychological distress is lower for older adults who believe that others stand ready to help in the future should the need arise. A detailed theoretical rationale is developed to explain these results. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Finite-element analysis and experimental study on tensile fatigue behaviour of bitumen–stone adhesion

Tensile fatigue behaviours of bitumen–stone adhesion were investigated using a dynamic mechanics analyser under stress‐controlled mode at two temperatures of 5 and 25°C and various controlled‐stress levels. Failure characteristics including interfacial failure and cohesive failure were examined using image analysis of fracture surfaces. Finite‐element analysis on stress distributions was conducted under different temperatures, film thickness and interfacial bonding conditions. A Coulomb–Mohr like criterion in combination with shear and normal stresses is proposed to deal with the extreme thin adhesive layer, which can be further simplified into an adhesive zone without significant loss of accuracy for stress analysis.     

Cardiovascular effects of conventional sulfonylureas and glimepiride

Sulfonylureas have, in the past, been reported to have adverse cardiovascular effects. Glimepiride is a new sulfonylurea. In spite of stimulating less insulin secretion, it has, depending on the species, equal or higher blood glucose decreasing activity and according to preliminary studies less cardiovascular activity than glibenclamide. Further studies were performed to confirm the lower cardiovascular activity of glimepiride. The IC50 for inhibition of rilmakalim-activated KATP channel currents in isolated ventricular myocytes was 31.6 nM for glimepiride and 6.8 nM for glibenclamide. In endotoxin shock-rats at a dose of 1 x 2 mg/kg i.v., glibenclamide induced a significantly higher blood pressure increase than glimepiride. At two i.v. doses of 20 mg/kg 4 min apart, in normal rats, glibenclamide produced signs of ischemia in the ECG in nearly all animals, glimepiride almost none, in diabetic rats, glibenclamide produced in all animals a lethal cardiogenic shock preceeded by serious ECG changes, glimepiride only in one fifth of the animals. In open-chest dogs, on intracoronary infusion of equieffective blood glucose-lowering doses, glibenclamide, gliclazide and glimepiride all reduced coronary blood flow, increased coronary resistance, depressed the mechanical activity of the heart, enhanced myocardial O2-extraction, reduced the serum potassium level and induced a moderate endocardial ST-segment elevation, but glimepiride to a significantly less extent than glibenclamide and gliclazide. The presented data confirm that glimepiride at equivalent blood glucose decreasing doses has less cardiovascular activity than conventional sulfonylureas.     

Eradication of Barrett''s mucosa with argon plasma coagulation and acid suppression: immediate and mid term results

Microcapsules are used for the formulation of drug controlled release and drug targeting dosage forms. Encapsulated hydrophobic drugs are often applied as their solutions in plant oils. The uptake of the oils in the complex coacervate microcapsules can be improved by the addition of surfactants. In this study, soybean, olive and peanut oils were chosen as the representatives of plant oils. The well characterized complex coacervation of gelatin and acacia has been used to produce the microcapsules. The amount of encapsulated oil has been determined gravimetrically. The encapsulation of the oils was high (75-80%). When the surfactants with HLB values from 1.8 to 6.7 were used, the amount of encapsulated oil was high (65-85%). A significant decrease of the oil content in the microcapsules was found when Tween 61 with HLB = 9.6 had been added into the mixture. No oil was found inside the microcapsules from the coacervate emulsion mixture containing Tween 81 (HLB = 10) and Tween 80 (HLB = 15), respectively. The results of the experiment confirm the dependence of hydrophobic substance encapsulation on the HLB published recently for Squalan.     

The attrition dilemma: Toward a new strategy for psychotherapy research.

Presents an analysis of the attrition dilemma in psychotherapy research and reviews the methods used to compensate for data loss. It is argued that attrition is not ultimately a problem of bias but a problem of lack of information. A reformulation is offered that integrates single-case studies with traditional group comparison methodology in an attempt to find optimal causal relations of treatments to outcomes. (10 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

降低氧化铝生产中熟料折合比的探讨

在氧化铝生产过程中，熟料折合比是烧结法一项重要的综合性指标，本文通过对熟料折合比的定义、计算公式的剖析，分析了生产过程中影响熟料折合比的主要因素，对有效降低熟料折合比的措施进行了探讨。     

清华屏蔽实验反应堆中子注量率能谱的调节和测量

叙述了采用多种屏蔽过滤方法,通过实验获得多种条件下的中子注量率能谱的调节和测量。     

基于PSOS的TM1300应用系统中的BSP研究

通过在应用软件与板级支持包BSP之间加一层库函数的方法较好地解决了应用程序与板级支持包函数间的通信问题，减少了板级支持包函数的维护复杂度，从而为嵌入式系统板级支持包的实现提供了一个有价值的思路。