Viscoelastic State for the Solutions of Spherically Symmetric Viscoelasticity Problems

The solutions of the spherically symmetric, linear, isothermal, and transient viscoelasticity problems via reciprocity theorem have been investigated for a specific material. The integral form of stress–strain relations has been used. The Laplace transform of a viscoelastic state, which is necessary for the integral equation arising as a result of reciprocity theorem, has been derived. This integral equation has been solved by Laplace transform. A sample problem has been solved to test the presented formulation. A numerical application of the analytic solution of this problem has been given.     

Grammar constraints

With the introduction of the Regular Membership Constraint, a new line of research has opened where constraints are based on formal languages. This paper is taking the next step, namely to investigate constraints based on grammars higher up in the Chomsky hierarchy. We devise a time- and space-efficient incremental arc-consistency algorithm for context-free grammars, investigate when logic combinations of grammar constraints are tractable, show how to exploit non-constant size grammars and reorderings of languages, and study where the boundaries run between regular, context-free, and context-sensitive grammar filtering.     

Effects of Different Oil Sources and Residues on Biomass and Metabolite Production by Yarrowia lipolytica YB 423-12

Yarrowia lipolytica is known to have the ability to assimilate hydrophobic substrates like triglycerides, fats, and oils, and to produce single-cell oils, lipases, and organic acids. The aim of the present study was to investigate the effects of different oil sources (borage, canola, sesame, Echium, and trout oils) and oil industry residues (olive pomace oil, hazelnut oil press cake, and sunflower seed oil cake) on the growth, lipid accumulation, and lipase and citric acid production by Y. lipolytica YB 423-12. The maximum biomass and lipid accumulation were observed with linseed oil. Among the tested oil sources and oil industry residues, hazelnut oil press cake was the best medium for lipase production. The Y. lipolytica YB 423-12 strain produced 12.32 ± 1.54 U/mL (lipase activity) of lipase on hazelnut oil press cake medium supplemented with glucose. The best substrate for citric acid production was found to be borage oil, with an output of 5.34 ± 0.94 g/L. The biotechnological production of valuable metabolites such as single-cell oil, lipase, and citric acid could be achieved by using these wastes and low-cost substrates with this strain. Furthermore, the cost of the bio-process could also be significantly reduced by the utilization of various low-cost raw materials, residues, wastes, and renewable resources as substrates for this yeast.     

Kinome-Wide Profiling Identifies Human WNK3 as a Target of Cajanin Stilbene Acid from Cajanus cajan (L.) Millsp.

Pigeon Pea (Cajanus cajan (L.) Millsp.) is a common food crop used in many parts of the world for nutritional purposes. One of its chemical constituents is cajanin stilbene acid (CSA), which exerts anticancer activity in vitro and in vivo. In an effort to identify molecular targets of CSA, we performed a kinome-wide approach based on the measurement of the enzymatic activities of 252 human kinases. The serine-threonine kinase WNK3 (also known as protein kinase lysine-deficient 3) was identified as the most promising target of CSA with the strongest enzymatic activity inhibition in vitro and the highest binding affinity in molecular docking in silico. The lowest binding affinity and the predicted binding constant pKi of CSA (−9.65 kcal/mol and 0.084 µM) were comparable or even better than those of the known WNK3 inhibitor PP-121 (−9.42 kcal/mol and 0.123 µM). The statistically significant association between WNK3 mRNA expression and cellular responsiveness to several clinically established anticancer drugs in a panel of 60 tumor cell lines and the prognostic value of WNK3 mRNA expression in sarcoma biopsies for the survival time of 230 patients can be taken as clues that CSA-based inhibition of WNK3 may improve treatment outcomes of cancer patients and that CSA may serve as a valuable supplement to the currently used combination therapy protocols in oncology.     

An Analytical Model for Compressive Creep Behavior of HDPE Used in Plastic Pipe Manufacturing

The creep behavior of high-density polyethylene has been studied by low compressive creep tests, and empirical results were analyzed and compared with analytically predicted results. The tests are performed upon ASTM standard specimens at various stress levels in the linear region. After these analyses, a mathematical model is derived and used to predict creep strain for long periods of time from the strain-time data obtained at different stresses over a time interval of 24 h.     

Determination of nutrients and volatile constituents of Agaricus bisporus (brown) at different stages

BACKGROUND: The physical properties, proximate composition, mineral and vitamin contents, and estimated volatile components of Portobello mushroom, Agaricus bisporus (brown), were analyzed in three flushes and at two different harvest times. The results showed different trends in the flushes and harvest terms studied. RESULTS: The mean values of texture, diameter, and protein of the harvested produce were 1.78–1.97 kg mm^?2, 4.67–5.02 cm, and 4.18–3.31% wet weight basis (wb), respectively. The mean Zn, Fe, P, Mg, K, Na, and Ca contents of both harvests (mg kg^?1 wb) were 8.15–7.07, 7.40–7.96, 1180.93–1038.69, 88.05–76.29, 213.29–238.82, 2652.0–2500.89, and 534.2–554.80, respectively. In terms of vitamin C, folic acid, thiamin, riboflavin, and niacin, the mean contents (mg kg^?1 wb) were 6.75–3.97, 0.09–0.08, 0.085–0.09, 0.27–0.29, and 3.62–2.94, respectively. The estimated volatile components comprised 18‐ or 16‐carbon compounds such as octadecanoic acid, hexadecanoic acid derivatives, and other important volatiles like dl‐limonene, n‐nonane, benzendicarboxylic acid, and cis‐linoleic acid esters. CONCLUSION: Nutritive contents and estimated volatiles of Portobello mushroom were evaluated in detail at different stages. Copyright © 2009 Society of Chemical Industry     

The Shear Stress–Strain Behaviour of Low-modulus Structural Adhesives

The shear stress–strain behaviour of two low-modulus structural adhesives has been measured using the butt-torsion test. The Nadai correction for non-linear shear behaviour is explained as it is necessary to understand how this correction can be applied to butt joints. The results for one adhesive were accurately used to predict the strength of a lap joint, and it was shown that the strength of such a joint can approach that of a conventional, modern, structural epoxy. Structural adhesives are usually reckoned to be those with a high strength (50 MPa and upwards) and (these days), a strain to failure of at least 10% in tension, and which usually have a tensile modulus of 2 GPa or so. However, adhesives which are significantly less stiff, less strong, but much more ductile are entering the ‘structural’ arena. In order to evaluate their effectiveness and use in design, it is necessary to be able to measure accurately their stress–strain behaviour. Two such materials are 3M 9245 Structural Bonding Tape (SBT) and 3M 7838 B/A.     

CIRCUMFERENTIAL CRACK PROBLEM FOR AN FGM CYLINDER UNDER THERMAL STRESSES

The main objective of this study is to determine the stress intensity factors associated with a circumferential crack in a thin-walled cylinder subjected to quasi-static thermal loading. The cylinder is assumed to be a functionally graded material. In order to make the problem analytically tractable, the thin-walled cylinder is modeled as a layer on an elastic foundation whose thermal and mechanical properties are exponential functions of the thickness coordinate. Hence a plane strain crack problem is obtained. First temperature and thermal stress distributions for a crack-free layer are determined. Then using these solutions, the crack problem is reduced to a local perturbation problem where the only nonzero loads are the crack surface tractions. Both internal and edge cracks are considered. Stress intensity factors are computed as functions of crack geometry, material properties, and time.     

Synthesis and Characterization of Nano‐Encapsulated Black Pepper Oleoresin using Hydroxypropyl Beta‐Cyclodextrin for Antioxidant and Antimicrobial Applications

Previous studies have reported antimicrobial and antioxidant activity of black pepper oleoresin which is associated to its phenolic compounds and piperine. The ability of cyclodextrins to form an inclusion complex with a guest molecule could improve black pepper oleoresin application, bioavailability, and stability in foods. Hydroxypropyl beta‐cyclodextrin (HPBCD) inclusion complex with black pepper olereosin were synthesized using the kneading method and characterized for its physico‐chemical properties and its antioxidant and antimicrobial activities. Inclusion complex size was 103.9 ± 7.6 nm and indicated to be a polydisperse system. The entrapment efficiency was 78.3 ± 3.6%, which suggests that other constituents in black pepper oleoresin have higher affinities for HPBCD than piperine (major compound in black pepper oleoresin). Thermograms showed the disappearance of oxidation peaks of black pepper oleoresin, proving complex formation with HPBCD. Phase solubility results indicated 1:1 stoichiometric inclusion complex formation and an increase of black pepper oleoresin aqueous solubility with HPBCD concentration. Nano‐encapsulation with HPBCD did not affect (P > 0.05) total phenolic content; however, it enhanced (P < 0.05) black pepper oleoresin antioxidant activity. Black pepper oleoresin and its inclusion complex were analyzed for their antimicrobial activity against Escherichia coli K12 and Salmonella enterica serovar Typhimurium LT2. Both free and encapsulated black pepper oleoresin effectively inhibited bacterial growth within the concentration range tested. Black pepper oleoresin encapsulated in HPBCD was able to inhibit Salmonella at lower (P < 0.05) concentrations than its corresponding free extract. Therefore, black pepper oleoresin‐HPBCD nanocapsules could have important applications in the food industry as antimicrobial and antioxidant system.