Goodbye, CRT

With many developed countries going fully digital in the near future, the entire television landscape is expected to change dramatically in the next few years. Plasma and LCDs as well as several new technologies including the surface-conduction electron-emitter display (SED) are vying to replace the 100-year old CRT. After examining the advantages and disadvantages each of these new options, the paper predicts that LCD televisions will dominate by 2010     

Calcium imaging of motoneuron activity in the en-bloc spinal cord preparation of the neonatal rat

1. This paper describes the use of calcium imaging to monitor patterns of activity in neonatal rat motoneurons retrogradely labeled with the calcium-sensitive dye, calcium green-dextran. 2. Pressure ejection of calcium green-dextran into ventral roots and into the surgically peeled ventrolateral funiculi (VLF) at the lumbar cord labeled spinal motoneurons and interneurons. The back labeled motoneurons often formed two or three discrete clusters of cells. 3. Fluorescent changes (10-20%) could be detected in labeled motoneurons after a single antidromic stimulus of the segmental ventral root. These changes progressively increased in amplitude during stimulus trains (1-5 s) at frequencies from 5 to 50 Hz, presumably reflecting a frequency-dependent increase in free intracellular calcium. 4. Stimulation of the ipsilateral VLF at the caudal lumbar level (L6), elicited frequency-dependent, synaptically induced motoneuronal discharge. Frequency-dependent fluorescent changes could be detected in calcium green-labeled motoneurons during the VLF-induced synaptic activation. 5. The spatial spread of synaptic activity among calcium green-labeled clusters of motoneurons could be resolved after dorsal root stimulation. Low-intensity stimulation of the roots produced fluorescence changes restricted to the lateral clusters of motoneurons. With increasing stimulation intensity the fluorescence change increased in the lateral cells and could spread into the medial motoneuronal group. After a single supramaximal stimulus a similar pattern was observed with activity beginning laterally and spreading medially. 6. Substantial changes in fluorescence of calcium green-labeled motoneurons were also observed during motoneuron bursting induced by bath application of the glycine receptor antagonist strychnine or the potassium channel blocker 4-aminopyridine (4-AP). 7. Our results show that membrane-impermeant fluorescent calcium indicators can be used as a tool to study the activity of specific populations of spinal neurons during execution of motor functions in the developing mammalian spinal cord. They also suggest that lateral clusters of motoneurons in the developing spinal cord of the rat are more recruitable or excitable than more medial clusters. Further understanding of these findings requires identification of these clusters.     

Adaptor realisations for wave switched-capacitor filters with reduced capacitance spread

The design of wave SC adaptors with very low capacitance spread is described and illustrated for the case of the unit-element cascade filter. The adaptors are canonic in the number of operational amplifiers and are parasitic-insensitive.     

Parental knowledge and choice regarding live and inactivated poliovirus vaccines

BACKGROUND: Concern about the 8 to 10 cases per year of vaccine-associated paralytic poliomyelitis caused by the live oral poliovirus vaccine (OPV) has led to revised guidelines for immunization of children in the United States. The use of inactivated poliovirus vaccine (IPV) at 2 and 4 months of age could require administration of 3 injections per visit until combination products are available. OBJECTIVE: To determine parents' knowledge of poliovirus vaccines and the choices they would make between IPV and OPV. METHODS: Parents of 240 children aged 2 weeks to 18 months under the care of 10 private pediatricians in the Baltimore, Md, metropolitan area were interviewed prior to the announcement of revised advisory committee guidelines. RESULTS: The majority (62.5%) of respondents were not aware that 2 poliovirus vaccines are available. After reviewing standardized information about the vaccines and 2 alternate schedules, most (75%) parents would consult someone (primarily their physician) before making a final choice of a vaccine schedule. If parents made the choice without consulting anyone else, 61.3% would choose to have their child receive IPV and 3 injections per visit as compared with an all-OPV schedule and 2 injections per visit. Inactivated poliovirus vaccine was preferred by most parents because it would reduce the risk for vaccine-associated paralytic poliomyelitis. Oral poliovirus vaccine was preferred by 37.9% of parents primarily because it was given orally. If the number of injections at each visit was the same for both vaccines, 76.3% of parents would choose the IPV schedule, and if the number of injections was reduced to 2 by combining IPV with another vaccine, 87.9% of parents would choose IPV. CONCLUSION: The number of injections per visit is an important issue, but a majority of parents would choose to have their children receive extra injections to prevent the low risk for vaccine-associated paralytic poliomyelitis.     

Genetic and environmental impact on protein profiles in barley and malt

Canadian barleys have higher protein content and better protein modification than Australian barleys. Protein and protein modification was investigated in two Australian and two Canadian barley varieties under different levels of nitrogen fertilisation. Mass spectrometry was used to analyse protein profiles in grain and malt to assess how genetic and environmental factors modified the proteins in grain and malt. The differences in grain protein between the Australian and Canadian varieties were mainly in the high molecular weight proteins, less in water soluble proteins and rarely in salt‐soluble proteins, while malt protein variations were observed in all three groups. Generally, Canadian varieties contained more proteins in grain, but less water soluble and salt soluble proteins in malt. Monitoring the protein modification during the malting indicated that more proteins were digested in Canadian varieties. Genetic factors were dominant for protein variation, although environment also affected the protein composition. Barley varieties growing in Canada generally contained slightly higher protein content, and nitrogen fertiliser influenced proteins in grain that ranged from 43,000 to 47,000 Da. The protein pattern of high fermentability and lower fermentability varieties mainly varied from 30,000 to 40,000 Da. © 2018 The Institute of Brewing & Distilling     

Effect of grass silage and concentrate based finishing strategies on cull dairy cow performance, carcass and meat quality characteristics

Sixty-eight spring calving Holstein-Friesian dairy cows on completion of lactation were randomly assigned to one of four dietary treatments. The experiment commenced on 17th December 2005 and was completed on 27th June 2006. Pre-experimental live weight and BCS were 605kg (s.d. 68.9) and 2.7 (s.d 0.28), respectively. The four treatments were: ad-lib grass silage (GS), GS+3kg concentrate (GS+3), GS+6kg concentrate (GS+6) and GS+9kg concentrate (GS+9). All cows were finished to a live weight>620kg and a BCS>3.5. Live animal, carcass and meat quality characteristics were measured. Mean (s.d.) total feed utilized was similar, at 1.5 (0.05) tonnes DM/cow across all treatments. There was a linear (P<0.001) increase in ADG (kg/day) for the first three dietary treatments, GS (0.71), GS+3 (0.91), GS+6 (1.14) with no additional response to the final increment, GS+9 (1.15). As concentrate proportion in the diet increased there was a linear decrease (P<0.001) in days to slaughter. Cows on the GS+9 treatment (84 days) finished on average 12, 25 and 38 days earlier than those on the GS+6, GS+3, and GS treatments. The GS+9 treatment had lower carcass fat yellowness ('b' value) than the GS treatment but the GS+3 and GS+6 treatments did not differ from either GS or GS+9. There was no effect of treatment (P>0.05) on muscle redness ('a' value) following exposure to oxygen. When cull cows are finished to pre-defined slaughter criteria, similar carcass classifications and carcass quality can be achieved with diets ranging from GS to GS+9, however significant difference in physical performance and days to slaughter will result.     

Genetics of grass dry matter intake, energy balance, and digestibility in grazing irish dairy cows

The objective of this study was to estimate genetic parameters for grass dry matter intake (DMI), energy balance (EB), and cow internal digestibility (IDG) in grazing Holstein-Friesian dairy cows. Grass DMI was estimated up to 4 times per lactation on 1,588 lactations from 755 cows on 2 research farms in southern Ireland. Simultaneously measured milk production and BW records were used to calculate EB. Cow IDG, measured as the ratio of feed and fecal concentrations of the natural odd carbon-chain n-alkane pentatriacontane, was available on 583 lactations from 238 cows. Random regression and multitrait animal models were used to estimate residual, additive genetic and permanent environmental (co)variances across lactations. Results were similar for both models. Heritability for DMI, EB, and IDG across lactation varied from 0.10 [8 days in milk (DIM)] to 0.30 (169 DIM), from 0.06 (29 DIM) to 0.29 (305 DIM), and from 0.08 (50 DIM) to 0.45 (305 DIM), respectively, when estimated using the random regression model. Genetic correlations within each trait tended to decrease as the interval between periods compared increased for DMI and EB, whereas the correlations with IDG in early lactation were weakest when measured midlactation. The lowest correlation between any 2 periods was 0.10, −0.36, and −0.04 for DMI, EB, and IDG, respectively, suggesting the effect of different genes at different stages of lactations. Eigenvalues and associated eigenfunctions of the additive genetic covariance matrix revealed considerable genetic variation among animals in the shape of the lactation profiles for DMI, EB, and IDG. Genetic parameters presented are the first estimates from dairy cows fed predominantly grazed grass and imply that genetic improvement in DMI, EB, and IDG in Holstein-Friesian cows fed predominantly grazed grass is possible.     

Inductive telemetry of multiple sensor modules

One of the many challenges associated with sensor networks is how to transmit data and power the sensors. Sensing multiple parameters in the environment requires miniaturized sensor nodes, relatively powerful programming platforms to interface with and process the data, and reliable long-term power solutions. Batteries provide the most obvious power source as long as the modules are reasonably big (a few square centimeters), easily accessible, and few in number so that the batteries can be easily replaced or recharged. In the vision of ubiquitous computing, where modules are embedded into everyday objects, computer hardware should be invisible and replacing batteries isn't compatible with this vision. Several solutions to the power problem exist, such as reducing power consumption to the point where batteries can last the module's lifetime. Another solution is energy scavenging - that is, extracting energy from ambient sources such as vibrations, hear, light, and water. A new approach provides a power source and fast communication for miniaturized modules' sensor nodes using a 13.56 MHz carrier. Although its powering range is limited, this method is well suited for applications in which communication must be fast but the sensor modules are hard to access.     

Canonic adaptor realisations for wave switched-capacitor filters

The principles of the design of canonic wave SC adaptors based on parasitic-insensitive voltage storage and subtraction are described. The adaptors may be used in any filter configuration and have a minimum number of operational amplifiers.     

Toughening effects of interleaved nylon veils on glass fabric/low‐styrene‐emission unsaturated polyester resin composites

The effectiveness of using interleaved nylon veils to increase the interlaminar toughness of glass fiber reinforced, low‐styrene emission unsaturated polyester resin composites has been investigated. Samples were manufactured by a hand lay‐up technique followed by compression moulding. Nylon 66 veils were used, with the veil content varying from 0% to 4% by weight. Double cantilever beam, short beam shear, and three point bend tests were performed. The increasing levels of nylon veil content improved the interlaminar toughness of the composites, which was characterized by critical strain energy release rate (G_IC). The maximum G_IC for crack propagation of a nylon interleaved composite increased by almost 170% over the baseline glass fiber reinforced composite. Dynamic Mechanical Analysis revealed an increase in the damping parameter of up to 117%. Image analysis via Digital Image Correlation and Scanning Electron Microscopy revealed increased fiber bridging between adjacent plies as a key reason for these improvements. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132, 41462.