The influence of socioeconomic and nutritional status on menarche in Nigerian school girls

Two once-daily electroconvulsive shocks (ECS) produced retrograde amnesia in rats trained on a Hebb-Williams maze; Verapamil (12.5 mg/kg, i.p.) or felodipine (10 mg/kg, p.o.) administered half an hour before each ECS attenuated this ECS-induced amnesia. Hence, these drugs may hold promise for the containment of amnesia induced by electroconvulsive therapy (ECT). Speculatively, one or more of several mechanisms may be involved: cerebral vasodilatation, enhancement of cholinergic tone, and inhibition of calcium-mediated impairment of neuronal function. These drugs may also act by attenuating the systolic surge in blood pressure during ECT, thereby decreasing edema due to cerebral hyperperfusion, as well as decreasing the possible transfer of potentially neurotoxic macromolecules through a putative breach in the blood-brain barrier.     

The 9p21 region in bladder cancer cell lines: large homozygous deletion inactivate the CDKN2, CDKN2B and MTAP genes

Homozygous and hemizygous deletions of 9p21 are the earliest and most common genetic alteration in bladder cancer. The identification of two cell cycle regulators, CDKN2 and CDKN2B, that map to the common region of deletion has prompted the hypothesis that they are critical tumor suppressor genes in this malignancy. However, controversy as to whether these genes are the only or even the most important target in bladder cancer oncogenesis remains. To more clearly determine the effect of these 9p21 alterations, we mapped the homozygous deletions and performed a detailed mutational and expression analysis for CDKN2, CDKN2B and a closely linked gene, methylthioadenoside phosphorylase (MTAP), in 16 established bladder cancer cell lines. Nine of the 16 lines exhibit large (30 to > 2000 kb) homozygous deletions on 9p21. All deletions include at least one exon of CDKN2, eight of nine include CDKN2B, and six of nine include MTAP. MTAP function correlates with the genomic deletions. SSCP and sequence analysis does not reveal any inactivating point mutations of CDKN2 or of CDKN2B in any of the cell lines without homozygous deletions, and all express the CDKN2 and the CDKN2B mRNA as well as the encoded p16 protein. The p16 protein levels vary widely and are correlated with absent pRb expression. We conclude that the 9p21 deletions in bladder cancer usually inactivate the CDKN2. CDKN2B, and MTAP genes but that CDKN2 is the most common target. Other mechanisms for inactivating this gene in bladder cancer appear to be uncommon.     

Duality transformations for general bi-isotropic (nonreciprocalchiral) media

The transformation is defined to leave a given bi-isotropic medium invariant, whence it is self-dual in this transformation. It is shown that duality transformations always exist in pairs, labeled as left-hand and right-hand transformations. Self-dual fields are seen to be generalizations of the wave fields E± applied in the analysis of reciprocal chiral media. It is demonstrated that plane wave propagation and reflection problems in bi-isotropic media can be solved easily in terms of self-dual field decompositions. Nonreciprocity is seen to give rise to effects like polarization rotation in reflection, which cannot be interpreted in terms of reciprocal chiral media     

Secure Multi-Party Computation without Agreement

It has recently been shown that authenticated Byzantine agreement, in which more than a third of the parties are corrupted, cannot be securely realized under concurrent or parallel (stateless) composition. This result puts into question any usage of authenticated Byzantine agreement in a setting where many executions take place. In particular, this is true for the whole body of work of secure multi-party protocols in the case that a third or more of the parties are corrupted. This is because these protocols strongly rely on the extensive use of a broadcast channel, which is in turn realized using authenticated Byzantine agreement. We remark that it was accepted folklore that the use of a broadcast channel (or authenticated Byzantine agreement) is actually essential for achieving meaningful secure multi-party computation whenever a third or more of the parties are corrupted. In this paper we show that this folklore is false. We present a mild relaxation of the definition of secure computation allowing abort. Our new definition captures all the central security issues of secure computation, including privacy, correctness and independence of inputs. However, the novelty of the definition is in decoupling the issue of agreement from these issues. We then show that this relaxation suffices for achieving secure computation in a point-to-point network. That is, we show that secure multi-party computation for this definition can be achieved for any number of corrupted parties and without a broadcast channel (or trusted pre-processing phase as required for running authenticated Byzantine agreement). Furthermore, this is achieved by just replacing the broadcast channel in known protocols with a very simple and efficient echo-broadcast protocol. An important corollary of our result is the ability to obtain multi-party protocols that remain secure under composition, without assuming a broadcast channel.     

Plane wave propagation in uniaxial bianisotropic medium

The uniaxial bianisotropic medium is a generalisation of the bi-isotropic and chiral media which recently have been subject to intensive research. Such a medium results, for example, when microscopic helices with parallel axes are positioned in a host dielectric in random locations. Plane wave propagation in such a medium is studied and a simple solution for the dispersion equation is found. Numerical examples for the wave number surfaces of the medium are given.<>