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1.
GN Mozhokina GB Sokolova OV Makarova LP Mikha?lova 《Canadian Metallurgical Quarterly》1996,41(7-8):31-33
The effect of lomefloxacin was studied on mice with experimental infection due to Mycobacterium tuberculosis. The antibiotic was administered in doses of 100 and 200 mg/kg. It was shown that the use of lomefloxacin for a month provided a lower death rate of the animals with progressing acute generalized tuberculosis, a lower level of the lesions in the internal organs and a lower number of the Mycobacterium isolates from them. The efficacy of the treatment depended on the drug dose. When lomefloxacin was used in a dose of 200 mg/kg, the survival rate was much higher and the number of the epithelial unicellular granulomas in the tissue of the lung and spleen was markedly decreased while with the lower dose the indices did not differ from those in the control. 相似文献
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VN Dobrovolsky OV Lagutin TV Vinogradova IS Frolova VP Kuznetsov OA Larionov 《Canadian Metallurgical Quarterly》1993,319(1-2):181-184
Transgenic mice carrying a hybrid gene consisting of ovine beta-lactoglobulin gene sequences and human gamma-interferon (hIFN-g) cDNA were produced. hIFN-g expression in the mammary gland of two lactating transgenic founder females was found. The concentration of active hIFN-g in the milk was estimated as being ca. 1800 IU/ml. The hIFN-g ability to express in the mammary gland was found in the progeny of transgenic founder male. 相似文献
4.
NV Tat'ianko LL Gromashevskaia AD Vovk MG Kasatkina OV Liashok VI Matiash SP Iasinovy? IaN Kovgan 《Canadian Metallurgical Quarterly》1996,(5-6):119-122
In this paper, characterization is given of clinical and biochemical features of VH B course against the background of narcomania. Recordable in such patient populations are high percentage of delta hepatitis (14.2%), unusual severity of the intoxication syndrome, protracted course with exacerbations (12.2%) and recurrences (8%), outcome being a chronic hepatitis (14.2%), slower normalization of biochemical indicators, persistently low ratio of AIAT activity in diluted and whole blood sera. The persistence of viral markers in drug addicts discharged from the hospital (68%) is fraught with danger of spreading viral hepatitis of prophylactic measures are not strictly observed. 相似文献
5.
OV Sivochalova 《Canadian Metallurgical Quarterly》1995,(9):1-4
Modern demographic situation stressed the problems of human reproductive health associated with industrial medical topics. The article suggests to regard a family (child and two parents) as a unit under study in industrial medicine. This methodic approach should work in scientific programs reviewing influence of industrial ecology and environmental factors on reproductivity. The authors suggest elaboration of universal strategy for ecologic and epidemiologic studies to form a scientific branch "Epidemiology of reproductive health" and to elaborate methods for better health management during the present demographic crisis. 相似文献
6.
NS Kislitsina BA Katsnel'son LI Privalova OV Driakhlova 《Canadian Metallurgical Quarterly》1995,(10):31-34
The authors proved that animals having higher natural antioxidant activity and lower intensity of lipid peroxidation are more resistant to fibrogenic effects of quartz. The peritoneal macrophages obtained from those animals show higher resistance to quartz exposure "in vitro". Parameters characterizing antioxidant system should be included into a group of indexes describing propensity to silicosis. 相似文献
7.
LIa Iukel'son OV Krasil'nikov EE Gussakovski? BA Tashmukhamedov 《Canadian Metallurgical Quarterly》1977,22(5):806-810
It has been stated that boiled for three hours haemocytocardiotoxin (HT) from cobra poison loses "direct" hemolytic activity and is unable to potentiate a haemolytic effect of phospholipase A. Surface activity of HT does not change. It is shown that in the course of heat denaturation the aggregation of toxin molecules to dimers and trimers takes place and electrophoretic mobility is decreased. The fluorescence of HT tyroxin residues supported the fact of its irreversible heat denaturation. 相似文献
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JANA TALASbreveOVÁ 《国际通用系统杂志》2013,42(4):645-654
This paper gives a brief summary of the linguistic fuzzy systems iheory and describes its possible application in econometric modelling. The essential feature of the used approach is a transformation of if-then rale bases into approximative deterministic behavior functions of considered economic systems. 相似文献
10.
T. ZIKMUND L. KVASNICA M. TÝČ A. KŘÍŽOVÁ J. ČOLLÁKOVÁ R. CHMELÍK 《Journal of microscopy》2014,256(2):117-125
Transmitted light holographic microscopy is particularly used for quantitative phase imaging of transparent microscopic objects such as living cells. The study of the cell is based on extraction of the dynamic data on cell behaviour from the time‐lapse sequence of the phase images. However, the phase images are affected by the phase aberrations that make the analysis particularly difficult. This is because the phase deformation is prone to change during long‐term experiments. Here, we present a novel algorithm for sequential processing of living cells phase images in a time‐lapse sequence. The algorithm compensates for the deformation of a phase image using weighted least‐squares surface fitting. Moreover, it identifies and segments the individual cells in the phase image. All these procedures are performed automatically and applied immediately after obtaining every single phase image. This property of the algorithm is important for real‐time cell quantitative phase imaging and instantaneous control of the course of the experiment by playback of the recorded sequence up to actual time. Such operator's intervention is a forerunner of process automation derived from image analysis. The efficiency of the propounded algorithm is demonstrated on images of rat fibrosarcoma cells using an off‐axis holographic microscope. 相似文献