全文获取类型
收费全文 | 1861篇 |
免费 | 19篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 5篇 |
综合类 | 4篇 |
化学工业 | 81篇 |
金属工艺 | 19篇 |
机械仪表 | 8篇 |
建筑科学 | 47篇 |
矿业工程 | 1篇 |
能源动力 | 7篇 |
轻工业 | 34篇 |
水利工程 | 1篇 |
无线电 | 28篇 |
一般工业技术 | 59篇 |
冶金工业 | 1561篇 |
原子能技术 | 1篇 |
自动化技术 | 25篇 |
出版年
2023年 | 3篇 |
2021年 | 4篇 |
2020年 | 4篇 |
2019年 | 3篇 |
2018年 | 6篇 |
2017年 | 6篇 |
2016年 | 4篇 |
2015年 | 7篇 |
2014年 | 4篇 |
2013年 | 21篇 |
2012年 | 11篇 |
2011年 | 22篇 |
2010年 | 24篇 |
2009年 | 13篇 |
2008年 | 15篇 |
2007年 | 18篇 |
2006年 | 16篇 |
2005年 | 8篇 |
2004年 | 13篇 |
2003年 | 14篇 |
2002年 | 9篇 |
2001年 | 15篇 |
2000年 | 16篇 |
1999年 | 53篇 |
1998年 | 480篇 |
1997年 | 254篇 |
1996年 | 182篇 |
1995年 | 121篇 |
1994年 | 83篇 |
1993年 | 90篇 |
1992年 | 10篇 |
1991年 | 16篇 |
1990年 | 23篇 |
1989年 | 30篇 |
1988年 | 27篇 |
1987年 | 18篇 |
1986年 | 15篇 |
1985年 | 13篇 |
1983年 | 3篇 |
1982年 | 8篇 |
1981年 | 7篇 |
1980年 | 17篇 |
1978年 | 6篇 |
1977年 | 48篇 |
1976年 | 92篇 |
1975年 | 5篇 |
1973年 | 5篇 |
1972年 | 3篇 |
1890年 | 4篇 |
1882年 | 2篇 |
排序方式: 共有1881条查询结果,搜索用时 15 毫秒
1.
ME Sutherlin I Nishimori T Caffrey EP Bennett H Hassan U Mandel D Mack T Iwamura H Clausen MA Hollingsworth 《Canadian Metallurgical Quarterly》1997,57(21):4744-4748
The levels of mRNA expression of three UDP-N-acetyl-alpha-D-galactosamine:polypeptide GalNAc N-acetylgalactosaminyltransferases (GalNAc-transferases) were quantified for human adenocarcinoma cell lines from pancreas, colon, stomach, and breast. Two of the GalNAc-transferases, GalNAc-T1 and GalNAc-T2, were expressed constitutively and at low levels in most or all cell lines examined. A third GalNAc-transferase, GalNAc-T3, was differentially expressed. Well-differentiated adenocarcinoma cell lines expressed high levels and moderately differentiated cell lines expressed lower levels of GalNAc-T3. Cell lines classified as poorly differentiated failed to express GalNAc-T3 mRNA at levels that could be detected by Northern blot analysis. Differential expression of the GalNAc-T3 protein was confirmed in these cell lines by Western blotting. We propose that glycosylation in tumor cell lines may be regulated in part by differential expression of GalNAc-transferases, and we suggest that GalNAc-T3 gene expression may be a molecular indicator of differentiated adenocarcinoma. 相似文献
2.
AG Niessen JG Bollemeijer RJ de Keizer PH de Meijer 《Canadian Metallurgical Quarterly》1994,138(15):770-775
OBJECTIVE: To assess how often the aetiology is established in patients with uveitis, what systemic disease are found and what is the contribution of the internist to the diagnostic process. DESIGN: Retrospective study. SETTING: University Hospital Leiden, the Netherlands. METHOD: From January 1987 to April 1992, 342 patients presented with uveitis. All patients underwent a standard ophthalmological examination. Referral to an internist and individualised laboratory screening followed in patients with recurrent, chronic, bilateral or panuveitis. Recorded were: ophthalmological data, results of laboratory screening, results of analysis by the internist, final diagnosis and presence of systemic disease. RESULTS: 149 (44%) patients were examined by the internist, 18 (5.2%) were seen by another specialist. In 169 (49%) patients a specific diagnosis was made. 74 (22%) had a systemic disease, 74 a primary ocular disease. In 28 (8%) a systemic disease was presumed (5% were HLA-B27 positive, 3% had abnormal laboratory results); 5 (1%) patients had endophthalmitis as a complication of a septic process. CONCLUSION: In approximately 1/3 of the patients with uveitis a systemic disease was found. Examination by the internist tailored to the individual patient is essential in the evaluation of uveitis patients. 相似文献
3.
MD Goldberg JR Canvin P Freestone C Andersen D Laoudj PH Williams IB Holland V Norris 《Canadian Metallurgical Quarterly》1997,79(6):315-322
In the bacterium Escherichia coli, H-NS-(H1, H1a) is a heat-stable protein with a molecular mass of 15.5 kDa involved in nucleoid organisation and gene regulation linked to certain signal transduction pathways. We have shown that, following addition of preparations of everted inner membrane vesicles, heat-stable cleavage products of approximately 10 kDa of H-NS are formed in vitro from newly synthesised, radio-labelled H-NS and from purified H-NS. The 15.5 kDa protein and its cleavage products were also recovered from a minicell system. These results raised the possibility that cleavage of H-NS is physiologically significant. However, the cleavage of H-NS observed appears to occur during cell breakage and to depend on the method of protein extraction and the presence of the outer membrane protease, OmpT. Nevertheless, the results indicate that H-NS may contain at least two separate domains with cleavage occurring between these domains at a preferred OmpT site. Failure to take account of H-NS cleavage in sample preparation and analysis can lead to serious underestimation of H-NS levels. 相似文献
4.
Acute and chronic antidepressant drug treatments respectively decrease and increase the aggressive behaviour of resident rats during encounters with unfamiliar conspecifics. We have now examined the effect of the 5-hydroxytryptamine1A receptor antagonist, WAY-100635, on fluoxetine-, paroxetine- or venlafaxine-induced changes in aggression. WAY-100635 (0.1 mg/kg), which did not modify behaviour when given alone, potentiated the venlafaxine (5.54 mg/kg)-induced reduction in aggression after acute treatment and, during chronic treatment, accelerated the fluoxetine (0.34 mg/kg/day)-induced increase in aggression, from day 5 to day 2. A similar change in time course was seen with paroxetine (0.33 mg/kg/day), although the increase in aggression was smaller. Venlafaxine (5.54 mg/kg/day, alone or co-administered with WAY-100635) increased aggression by day 2. During chronic treatment, therefore, venlafaxine, at the dose used, had a more rapid onset of action than either fluoxetine or paroxetine, whereas the fluoxetine- and paroxetine-, but not the venlafaxine-, induced increase in aggression was accelerated by WAY-100635. These studies further support the hypothesis that selective blockade of the 5-hydroxytryptamine1A receptor augments the effects of antidepressant drugs in an animal model predictive of antidepressant activity, presumably by concomitant blockade of the somatodendritic 5-hydroxytryptamine1A autoreceptor-mediated negative feedback system of serotonergic neurones. 相似文献
5.
6.
Wilhelm Conrad Roentgen's discovery of the X-ray one century ago has been ranked in importance with the discovery and development of anesthesia and the discovery of microorganisms and their role in disease. Roentgen's scientific devotion and the persistence of C. Edmund Kells, who took Roentgen's discovery and applied it to dentistry, had a great impact on how dentists practice today. 相似文献
7.
PB Imrey LA Jackson PH Ludwinski AC England GA Fella BC Fox LB Isdale MW Reeves JD Wenger 《Canadian Metallurgical Quarterly》1996,143(6):624-630
Between February 1991 and April 1992, eight undergraduates at a US residential university and one at a nearby 2-year college contracted serogroup C meningococcal disease. A case-control investigation with 20 controls per case, oropharyngeal carriage surveys, and multilocus enzyme electrophoresis (MEE) of serogroup C isolates were used to identify factors contributing to the outbreak. All eight sterile-site isolates from cases were closely related by MEE and were similar (though not identical) to the strain associated with the 1991-1992 epidemic of meningococcal disease in eastern Canada. Disease was associated with cigarette smoking (p = 0.012), recent patronage of campus-area bars (p = 0.034), estimated amount of time spent in campus-area bars (p = 0.0003), and, especially, recent patronage of one specific bar, bar A (p = 0.0006; odds ratio = 23.1, 95% confidence interval 3.0-571.5). In carriage surveys, 1,528 throat cultures taken from (primarily student) noncases yielded only five (0.3%) strains that were identical by MEE to those from cases. Two of these were found among 22 cultures obtained from bar A employees in spring 1992. Some cases in this outbreak may have followed transmission of the epidemic strain in bar A. Campus bar environments may facilitate the spread of meningococcal disease among teenagers and young adults. 相似文献
8.
A meta-analysis was conducted to identify information processing factors that characterise children with Developmental Coordination Disorder (DCD). A total of 50 studies yielded 374 effect sizes based on 983 DCD and 987 control children. A mild generalised performance deficit was indicated, since motor-impaired children were inferior on almost all measures of information processing. There were, however, several areas where their deficiencies were more pronounced. The greatest deficiency was in visual-spatial processing. This was evident regardless of whether or not the tasks involved a motor component. Most other deficiencies were in the small-to-moderate range and included kinaesthetic and cross-modal processing. The findings support the notion that perceptual problems, particularly in the visual modality, are associated with difficulties in motor coordination. 相似文献
9.
K. Lefmann B. Lake G. Aeppli S.-W. Cheong N. B. Christensen K. N. Clausen S. Hayden T. E. Mason D.F. McMorrow H. A. Mook H. M. Rønnow H. Takagi 《Journal of Low Temperature Physics》2004,135(5-6):621-664
One important area of modern condensed matter research is the investigation of the nature of the superconducting cuprates. Much progress in this field has been obtained with the technique of neutron scattering. We here present a review of neutron scattering studies of the high-temperature superconductor La2?xSrxCuO4, performed at Risø National Laboratory. We review the work on the mapping of the incommensurate spin fluctuations, the investigation of the gap in the fluctuation spectrum, the magnetic properties of the vortices appearing in an applied field, and the quantum critical behaviour of the system. We discuss our findings in the light of results of neutron scattering from other groups, on other cuprate systems, and results from other experimental methods, e.g. NMR, μSR, STM, X-ray diffraction, and ARPES. We end with a discussion on the implications of the experimental results for the progress in the general understanding of high-temperature superconductivity. PACS numbers: 61.12.Ex, 74.20.Mn, 74.72.Dn, 75.25.+z, 78.70.Nx. 相似文献
10.
Michael Clausen 《Journal of Symbolic Computation》1991,11(5-6)
This paper is concerned with structural and algorithmic aspects of certain R-bases in polynomial rings R[Xij] over a commutative ring R with 1. These bases are related to standard tableaux. We shall examine the main tools in full detail: (symmetrized) bideterminants, Capelli operators, hyperdominance, and generalized Laplace's expansions. These tools are then applied to the representation theory of symmetric groups. In particular, we present an algorithm which efficiently computes for every skew module of a symmetric group an R-basis which is adapted to a Specht series. This result is a constructive, characteristic-free analogue of the celebrated Littlewood-Richardson rule. This paper will serve as the basis for a possible generalization of that rule to more general shapes. 相似文献