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排序方式: 共有497条查询结果,搜索用时 19 毫秒
1.
L Giorgi A Di Filippo A Franchini L Rizzo S Benvenuti M Conti GP Novelli 《Canadian Metallurgical Quarterly》1994,60(1-2):43-47
OBJECTIVE: The reflex response to orotracheal intubation provokes an increase of arterial pressure accompanied by an increase of chorioides volume and a consequent ocular hypertone. There are several methods to reduce the reflex response due to intubation. One of the most effective is topical anaesthesia of larynx and trachea. Experiments were directed to evaluate the efficacy of topical anaesthesia to reduce the intraocular hypertone due to orotracheal intubation. DESIGN: A prospective randomized mask study was conduct on patients undergoing ophthalmologic (anterior segment) surgery at the Eye Clinic of Florence University. METHODS: Intraocular pressure was measured by a Goldman tonometer at four times: T0 = basal, T1 = 2' minutes after induction of general anaesthesia, T2 = 2' minutes after laryngoscopy, T3 = 2' minutes after orotracheal intubation. At the same moments, systolic blood pressure, heart rate, rate pressure pro duct were measured. Patients were randomly divided in two groups: Group L (n = 10) in which was evaluated the efficacy of laryngotracheal topical spray of lidocaine 4% (2 ml) and Group F (n = 10) in which saline was used instead of anesthetic. The filling of the LTA kit (Abbott) was made by a person not involved in the experiments. DATA ANALYSIS: Student's t test for unpaired data. RESULTS: Topical anaesthesia reduces the increase of intraocular pressure, hypertension and rate pressure product due to intubation. The intraocular pressure reduces to 13% less than basal value in Group L and increase to 50% more than basal value in Group F. CONCLUSION: The topical anaesthesia of larynx and trachea is effective to reduce the intraocular hypertension due to the reflex response evoked by orotracheal intubation. 相似文献
2.
N Rizzo MC Pittalis G Pilu A Perolo C Banzi A Visentin L Bovicelli 《Canadian Metallurgical Quarterly》1996,16(2):159-163
The participation of sarcoplasmic reticulum Ca2+ release channels in the activation of Ca(2+)-sensitive K+ currents (IK(Ca)) by cyclic dibutyryl GMP was investigated in smooth muscle cells from the circular layer of guinea-pig gastric fundus. All experiments were performed in the presence of 3 microM nicardipine into the bath and low Ca2+ buffering capacity of the pipette-filling solution (pCa 7.4). Ruthenium red (10 microM) as well as its combination with 10 microM heparin abolished the cyclic GMP-induced activation of IK(Ca), while 10 microM heparin remained ineffective. Ryanodine (10 microM) and the subsequently added 1 microM thapsigargin induced a relatively small increase in IK(Ca) amplitudes. The addition of 10 microM ryanodine to 1 microM thapsigargin-containing bath solution caused a vast increase in IK(Ca). It is hypothesyzed that protein kinase G-induced vectorial Ca2+ flux from the cell bulk and sarcoplasmic reticulum Ca2+ stores toward the plasma membrane is realized by a spontaneous Ca(2+)-induced Ca2+ release from a superficially situated Ca2+ store. 相似文献
3.
Fortuna L. Frasca M. Rizzo A. 《IEEE transactions on instrumentation and measurement》2003,52(6):1809-1814
Ultrasonic devices are widely used in robotics as exteroceptive sensors for ranging measurements. Robotic applications often involve a large number of sonars operating concurrently, giving rise to the phenomenon of crosstalk. In this work, the problem of improving performance of ultrasonic devices in the presence of crosstalk and noise is addressed. In order for each device to discriminate its own echo, chaos is exploited to create unique firing sequences. In particular, the firing scheme described in this work is inspired to a modulation scheme used in chaotic communications, called chaotic pulse position modulation (CPPM). The evaluation of the time of flight is performed by a detection filter. The experimental setup consists of a Polaroid 600 electrostatic transducer driven by a continuous CPPM modulator. Experimental results confirm the suitability of the approach. 相似文献
4.
5.
Teoman Dogru Ali Kirik Hasan Gurel Ali A. Rizvi Manfredi Rizzo Alper Sonmez 《International journal of molecular sciences》2021,22(12)
Nonalcoholic fatty liver disease (NAFLD) is strongly associated to the features of metabolic syndrome which can progress to cirrhosis, liver failure and hepatocellular carcinoma. However, the most common cause of mortality in people with NAFLD is not liver-related but stems from atherosclerotic cardiovascular disease (CVD). The prevalence of NAFLD is on the rise, mainly as a consequence of its close association with two major worldwide epidemics, obesity and type 2 diabetes (T2D). The exact pathogenesis of NAFLD and especially the mechanisms leading to disease progression and CVD have not been completely elucidated. Human fetuin-A (alpha-2-Heremans Schmid glycoprotein), a glycoprotein produced by the liver and abundantly secreted into the circulation appears to play a role in insulin resistance, metabolic syndrome and inflammation. This review discusses the links between NAFLD and CVD by specifically focusing on fetuin-A’s function in the pathogenesis of NAFLD and atherosclerotic CVD. 相似文献
6.
The fatty acid composition of the membrane phospholipids phosphatidylcholine (PC) and phosphatidylethanolamine in insulin-sensitive
Type I (soleus) and insulin-resistant Type II (EDL) muscle is not known. In the present studies, soleus and EDL muscles were
removed from 250–300 g Sprague-Dawley rats, and the fatty acid composition of total and individual phospholipid (PL) species
was quantitated. As expected, triglyceride content was increased twofold in soleus muscle. No quantitative differences in
the individual PL species or cholesterol content were found between the two muscles. However, a striking difference in PL
fatty acid composition was observed in the PC fraction. An increase in 16∶0 with decreases in 18∶0, 18∶1, 22∶5n-3, and 22∶6n-3
(P<0.001 for each) was observed in the PC fraction of EDL compared to that from soleus, consistent with reduced elongation of
PC fatty acids. Inhibition of fatty acid oxidation with the carnitine palmitoyl transferase-1 inhibitor, etomoxir, did not
alter the fatty acid pattern in either muscle. We conclude that an alteration in PL fatty acid composition consistent with
reduced elongation of both saturated and unsaturated fatty acids is observed in Type II muscle. The restriction of these alterations
to the PC fraction has important implications.
Deceased (June 28, 1996). 相似文献
7.
G. Neri G. Rizzo S. Galvagno A. Donato M. G. Musolino R. Pietropaolo 《Applied catalysis. B, Environmental》2003,42(4):381-391
Alkali-doped FeV oxide catalysts supported on -alumina were prepared and their catalytic activity in the combustion of diesel soot is reported. The catalysts were characterized by XRD, TPR and SEM–EDX analysis. The influence of the nature of the alkali metal (K and Cs), the temperature of treatment of the catalysts and the stability to sulfur poisoning have been investigated.
Catalysts doped with Cs were the most active and stable also after several combustion cycles and in the presence of sulfur in the stream. The activity measurements and microstructural results suggest that the combustion of soot is favored on catalysts where amorphous phases and/or mixed Fe---V---O phases, ensuring an intimate contact between iron and vanadium, are present. A reaction mechanism involving the participation of the redox couple Fe(II)–Fe(III) in the activation of the vanadium combustion sites, is proposed. 相似文献
8.
Malta Loretta S. Giosan Cezar Szkodny Lauren E. Altemus Margaret M. Rizzo Albert A. Silbersweig David A. Difede JoAnn 《Virtual Reality》2021,25(2):293-302
Virtual Reality - This research report describes the development of a virtual reality (VR) laboratory stressor to study the effects of exposure to stressful events. The aim of the research was to... 相似文献
9.
The corrosion of the two pure metals and of two alloys containing 15 and 30 wt% Nb has been studied at 600–800°C in H2-H2S-CO2 gas mixtures providing 10−8 atm S2 at all temperatures and 10−24 atm O2 at 600°C and 10−20 atm O2 at 700 and 800°C. The corrosion kinetics were rather complex, being sometimes parabolic and in other cases nearly linear. Under a constant temperature the addition of niobium generally reduced the corrosion rate, except at 700°C when pure cobalt corroded more slowly than the two alloys. The corrosion rates for the same material decreased with an increase in temperature under the same sulfur pressure. Except at 800°C under 10−8 atm S2, which is below the dissociation pressure of cobalt sulfide, the scales presented an outer layer of pure cobalt sulfide and an inner layer of complex composition containing a mixture of double sulfide, niobium oxide and in some cases of unreacted metallic cobalt particles. The addition of niobium was generally beneficial, the effect increasing with its concentration in the alloy, but the corrosion rates of the alloys were still much higher than that of pure niobium, mainly as a result of the lack of formation of a protective layer of niobium sulfide. The corrosion behavior is examined with special reference to the consequences of the low solubility of niobium in cobalt and to the relation between the microstructure of the alloys and the scales. 相似文献
10.
The corrosion of M–Nb alloys based on iron, cobalt, and nickel and containing 15 and 30 wt% Nb has been studied at 600–800°C under low oxygen pressures (10–24 atm at 600°C and 10–20 atm at 700–800°C). Except for the Co–Nb and Ni–Nb alloys corroded at 800°C, which formed external scales of niobium oxides, corrosion under low O2 pressures produced an internal oxidation of niobium. This attack was much faster than expected on the basis of the classical theory. Furthermore, the distribution of the internal oxide in the alloys containing two metal phases was very close to that of the Nb-rich phase in the original alloys. These kinetic, microstructural, and thermodynamic aspects are examined by taking into account the effects of the limited solubility of niobium in the various base metals and of the two-phase nature of the alloys. 相似文献