Absence of detectable human herpesvirus 8 in the semen of human immunodeficiency virus-infected men without Kaposi's sarcoma

The prevalence of human herpesvirus 8 (HHV-8)/Kaposi's sarcoma (KS)-associated herpesvirus was investigated in the semen of 99 human immunodeficiency virus (HIV)-infected men (median CD4 cell count, 357/mm3) by use of a polymerase chain reaction (PCR) assay capable of detecting <10 copies of HHV-8 DNA. Of the subjects, 95 (96%) self-identified as men who have sex with men (MSM), and 3 had a history of clinical KS. Seminal cell specimens were negative for HHV-8 in 98 subjects. None of the 26 without KS (27.1% of 96 tested) who were seropositive for HHV-8 by IFA for latency-associated nuclear antigens had HHV-8 detected in their semen. The only subject with any evidence for seminal HHV-8 DNA was seropositive for HHV-8 and had active KS. HHV-8 was detected in 10 (10.4%) of 96 peripheral blood mononuclear cell specimens. The prevalence of HHV-8 DNA by PCR in semen of HIV-infected MSM without KS is low.     

In-situ-Messung der Stickoxidkonzentration in turbulenten Diffusionsflammen

Zusammenfassung Die laserspektroskopischen Me?methoden laserinduzierte Fluoreszenz und spontane Ramanspektroskopie werden eingesetzt zur Messung der Konzentrationen von Stickoxid, Hydroxyl sowie der chemischen Hauptkomponenten und der Temperatur. Betrachtet wird die thermische Umsetzung von Wasserstoff mit Luftsauerstoff. Es wird die experimentelle Vorgehensweise und Problematik dargestellt. Ebenso wird der Weg der Modellierung und Berechnung turbulenter Verbrennungsvorg?nge am konkreten Beispiel skizziert. Die Annahme chemischen Gleichgewichts stellt sich als ungenügend in der Berechnung der Stickoxid- und Hydroxylkonzentrationen heraus. Eine deutlich bessere Vorhersage wird durch Einführen einer Reaktionsfortschrittsvariablen für das chemische Modell erreicht.     

Effects of acetylcholine and glutamate on isolated neurons of locomotory network of Clione

In Clione limacina, locomotory rhythm is produced in the central pattern generator by reciprocal activity of two groups of interneurons. Dorsal (D) and ventral (V) phase interneurons activate neurons of the same phase and inhibit neurons of the opposite phase. Which neurotransmitters are used by these interneurons is not clear. In this study, identified follower neurons to V and D interneurons were isolated, and their responses to the local application of potential neurotransmitters were examined. Acetylcholine exerted inhibitory action on the isolated D-phase neurons and excitatory action on V-phase neurons. Glutamate produced excitation in D-phase neurons, and inhibition in V-phase neurons. These results suggest that acetylcholine is the neurotransmitter of D-phase interneurons, while glutamate might be the neurotransmitter of V-phase interneurons.     

Steps towards a consumer-driven ‘concept innovation machine’ for food and drink

Innovation is often left to insight and serendipity. A lot of what researchers call innovation is actually a process by which one can make the individual consumer or practitioner more ‘creative’. Although it is important to work with the creative individual in hopes of coming up with the better ‘idea’ and new product/service opportunity, an equally valid albeit novel and counterintuitive approach systematizes creativity in a ‘research-driven machine’. This paper presents an approach to the systematization, based upon the point of view that creativity and innovation comprise the recombination of components into new blends. Given this point of view, to then spur innovation requires a systematic database that the user can access, with tools to help manipulate that database. The paper shows how such a database can be constructed and then used to create a novel product. The approach provides a general framework for the sensory professional to become more involved in the early stages of product development, where the focus is on the conceptual aspects of food features rather than on their physical manifestations in actual products.     

Experimentelle Bestimmung der spezifischen elektrischen Leitfähigkeit hoch CaF2-haltiger Schlacken

In a comprehensive literature study applied measurement methods for determination of the specific electrical conductivity of slags were compared. Based on these conclusions, a Tammann furnace was modified to a conductivity measuring system with four electrodes. A qualitative and quantitative comparison of results from literature with the practical results of multiple investigations of CaF₂ slags with a purity of 99.5% was carried out.