Key competencies of the psychodynamic psychotherapist and how to teach them in supervision.

Four of Rodolfa et al.’s (2005) competencies in professional psychology—relationship, self-reflection, assessment-case conceptualization, and intervention—are key for the psychodynamic psychotherapist. Relationship lies at the heart of what is understood to be curative about psychodynamic psychotherapy. Self-reflection implies a complex and highly developed process that includes but goes beyond Rodolfa et al.’s and Kaslow, Dunn, and Smith’s (2008) definitions. Competent assessment, diagnosis, and case conceptualization entails making inferences about unconscious processes by observing the client and also one’s own experience, and integrating these inferences with theory. Effective psychodynamic intervention is derived from what the psychotherapist has experienced, processed, and conceptualized about the relationship with the client and about the client’s internal object world. An extended vignette shows these competencies emerging in a psychotherapist-in-training, facilitated by an intense interaction with a supervisor. Although the supervisory and clinical tasks are different, the supervisor provides a relationship experience that models these same competencies for the supervisee and catalyzes their development in the supervisee. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Estimating ground-level PM2.5 in the eastern United States using satellite remote sensing

An empirical model based on the regression between daily PM2.5 (particles with aerodynamic diameters of less than 2.5 microm) concentrations and aerosol optical thickness (AOT) measurements from the multiangle imaging spectroradiometer (MISR) was developed and tested using data from the eastern United States during the period of 2001. Overall, the empirical model explained 48% of the variability in PM2.5 concentrations. The root-mean-square error of the model was 6.2 microg/m3 with a corresponding average PM2.5 concentration of 13.8 microg/m3. When PM2.5 concentrations greater than 40 microg/m3 were removed, model results were shown to be unbiased estimators of observations. Several factors, such as planetary boundary layer height, relative humidity, season, and other geographical attributes of monitoring sites, were found to influence the association between PM2.5 and AOT. The findings of this study illustrate the strong potential of satellite remote sensing in regional ambient air quality monitoring as an extension to ground networks. With the continual advancement of remote sensing technology and global data assimilation systems, AOT measurements derived from satellite remote sensors may provide a cost-effective approach as a supplemental source of information for determining ground-level particle concentrations.     

Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study

Twenty-one neonates of over 36 weeks' gestation suffered perinatal asphyxia but not chronic hypoxia. Three clinical stages of postanoxic encephalopathy were distinguished. Stage 1 lasted less than 24 hours and was characterized by hyperalertness, uninhibited Moro and stretch reflexes, sympathetic effects, and a normal electroencephalogram. Stage 2 was marked by obtundation, hypotonia, strong distal flexion, and multifocal seizures. The EEG showed a periodic pattern sometimes preceded by continuous delta activity. Infants in stage 3 were stuporous, flaccid, and brain stem and autonomic functions were suppressed. The EEG was isopotential or had infrequent periodic discharges. Infants who did not enter stage 3 and who had signs of stage 2 for less than five days appeared normal in later infancy. Persistence of stage 2 for more than seven days or failure of the EEG to revert to normal was associated with later neurologic impairment or death.     

Using sulfur as a tracer of outdoor fine particulate matter

Six homes in the metropolitan Boston area were sampled between 6 and 12 consecutive days for indoor and outdoor particle volume and mass concentrations, particle elemental concentrations, and air exchange rates (AERs). Indoor/outdoor (I/O) ratios of nighttime (i.e., particle nonindoor source periods) sulfur, PM2.5 and the specific particle size intervals were used to provide estimates of the effective penetration efficiency. Mixed models and graphical displays were used to assess the ability of the I/O ratios for sulfur to estimate corresponding I/O ratios for PM2.5 and the various particle sizes. Results from this analysis showed that particulate sulfur compounds were primarily of outdoor origin and behaved in a manner that was representative of total PM2.5 in Boston, MA. These findings support the conclusion that sulfur can be used as a suitable tracer of outdoor PM2.5 for the homes sampled in this study. Sulfur was more representative of particles of similar size (0.06-0.5 microm), providing evidence that the size composition of total PM2.5 is an important characteristic affecting the robustness of sulfur-based estimation methods.     

Unimpaired RNA synthesis in neurons and epithelial cells in a freshwater leech exposed to the organophosphate insecticide chlorpyrifos

Chlorpyrifos (Dursban) is an organophosphate insecticide widely used mainly for control of mosquito larvae. This study used the dominant freshwater leech Nephelopsis obscura as a representative aquatic invertebrate to test toxicity of chlorpyrifos on a nontarget species. RNA synthesis in neurons of the cerebral ganglion, epithelial cells of the intestine, and the tegument of small immature (50-70 mg) and large mature (300-400 mg) N. obscura was examined histochemically with acridine orange fluorochrome after exposure to chlorpyrifos in concentrations of 16, 32, 64, 128, and 144 ppb for as long as 6 weeks. The maximum environmental concentration of this insecticide in lake water, when used properly, is 4.25 ppb. There was no mortality, and no behavioral changes were observed in experimental animals, except for transient curling and cutaneous mucus secretion at the highest concentrations of chlorpyrifos. No pathological changes were observed in the intensity of RNA fluorescence or in the distribution of RNA within the cytoplasm of neurons or epithelial cells in any specimens, unlike N. obscura exposed to anoxia, hyperoxia, or salinity. Chlorpyrifos in the concentrations studied does not appear to adversely affect nucleic acid metabolism in N. obscura.     

Spatial variability of carbonaceous aerosol concentrations in East and West Jerusalem

Carbonaceous aerosol concentrations and sources were compared during a year long study at two sites in East and West Jerusalem that were separated by a distance of approximately 4 km. One in six day 24-h PM(2.5) elemental and organic carbon concentrations were measured, along with monthly average concentrations of particle-phase organic compound tracers for primary and secondary organic aerosol sources.Tracer compounds were used in a chemical mass balance ICMB) model to determine primary and secondary source contributions to organic carbon. The East Jerusalem sampling site at Al Quds University experienced higher concentrations of organic carbon (OC) and elemental carbon (EC) compared to the West Jerusalem site at Hebrew University. The annual average concentrations of OC and EC at the East Jerusalem site were 5.20 and 2.19 μg m(-3), respectively, and at the West Jerusalem site were 4.03 and 1.14 μg m(-3), respectively. Concentrations and trends of secondary organic aerosol and vegetative detritus were similar at both sites, but large differences were observed in the concentrations of organic aerosol from fossil fuel combustion and biomass burning, which was the cause of the large differences in OC and EC concentrations observed at the two sites.     

Factors influencing relationships between personal and ambient concentrations of gaseous and particulate pollutants

Previous exposure studies have shown considerable inter-subject variability in personal-ambient associations. This paper investigates exposure factors that may be responsible for inter-subject variability in these personal-ambient associations. The personal and ambient data used in this paper were collected as part of a personal exposure study conducted in Boston, MA, during 1999-2000. This study was one of a group of personal exposure panel studies funded by the U.S. Environmental Protection Agency's National Exposure Research Laboratory to address areas of exposure assessment warranting further study, particularly associations between personal exposures and ambient concentrations of particulate matter and gaseous co-pollutants. Twenty-four-hour integrated personal, home indoor, home outdoor and ambient sulfate, elemental carbon (EC), PM_2.5, ozone (O₃), nitrogen dioxide (NO₂) and sulfur dioxide were measured simultaneously each day. Fifteen homes in the Boston area were measured for 7 days during winter and summer. A previous paper explored the associations between personal-indoor, personal-outdoor, personal-ambient, indoor-outdoor, indoor-ambient and outdoor-ambient PM_2.5, sulfate and EC concentrations. For the current paper, factors that may affect personal exposures were investigated, while controlling for ambient concentrations. The data were analyzed using mixed effects regression models. Overall personal-ambient associations were strong for sulfate during winter (p < 0.0001) and summer (p < 0.0001) and PM_2.5 during summer (p < 0.0001). The personal-ambient mixed model slope for PM_2.5 during winter but was not significant at p = 0.10. Personal exposures to most pollutants, with the exception of NO₂, increased with ventilation and time spent outdoors. An opposite pattern was found for NO₂ likely due to gas stoves. Personal exposures to PM_2.5 and to traffic-related pollutants, EC and NO₂, were higher for those individuals living close to a major road. Both personal and indoor sulfate and PM_2.5 concentrations were higher for homes using humidifiers. The impact of outdoor sources on personal and indoor concentrations increased with ventilation, whereas an opposite effect was observed for the impact of indoor sources.     

Neuroblastic migration: embryological aspects and mechanisms

INTRODUCTION: The migration of immature neurons of the cerebrum is genetically programmed from the primitive neuroepithelium before the end of the final mitotic cycle. The orientation of the mitotic spindle determines when a neuroepithelial cell is ready to start migration and the proportion of major genetic material it is destined to receive. DEVELOPMENT: The gene LIS1, defective in lissencephaly type 1 of Miller and Dieker, is expressed in the neuroepithelial cells, in the ependyma and the Cajal-Retzius neurons. These transitory fetal cells are the first neurons of the cerebral cortex. Most of the neurons of the cortical plate arrive by means of glial radial cells which guide them towards their destination. Cell adhesion molecules from the neuroblasts themselves, the glial radial cell, the extracellular matrix and perhaps the ependymal cells are important in adhering the neuroblasts to the glial radial cells. Genetic deficiency of these molecules results in defective migration. The mechanism of cellular movement is still not fully understood. Disorders of migration may also be induced by non-genetic factors, such as infarcts or other lesions which damage or destroy the glial radial fibres during the fetal period.     

Reuniting the psychic couple in analytic training and practice: A candidate's experience.

In the course of training at a comparative psychoanalytic institute, the author fixed upon a technical question: how to find optimal psychological distance from her patients. She struggled to integrate the diverse perspectives that the literature provided on this question. She also became aware of a conflictual phantasy of a polarizing internal mother and father that underlay her interest in the question. A dream about her work with a control patient eventually allowed her, with the aid of both supervisor and personal analyst, to work through the phantasy, and to bring her internal "psychic couple" into creative contact with one another. As a result, her capacity to analyze her patient increased. The author concludes that when supervisors and seminar leaders (in addition to the candidate's analyst) make themselves available to unconscious aspects of a candidate's learning process, institutes provide a more spacious container for psychoanalytic development. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Human cerebellar hypoplasia: a syndrome of diverse causes

Seven children had congenitally small cerebella. Perinatal asphyxia was not a factor. Clinical signs in infancy were generalized muscular hypotonia, delayed development, truncal titubation, and intention tremor. Most had fixation nystagmus and esotropia. Three had seizures and an abnormal EEG. Pneumoencephalography in each case revealed a small cerebellum with prominent folia, large fourth ventricle, wide vallecula, large cisterna magna, and normal lateral and third ventricles. A computerized tomography scan in one case showed similar findings. One patient had an absent corpus callosum. One patient died at 2 1/2 years. The cerebellar hemispheres and vermis were small. Granular cells were absent throughout. Purkinje's cells were preserved, but had dendritic swellings with radiating fibrils. Cerebellar, pontine, and inferior olivary nuclei showed mild neuronal loss. The clinical and pathologic findings resemble those of animal models of cerebellar hypoplasia produced by fetal exposure to certain viruses, toxins, or repeated low doses of radiation. Cerebellar hypoplasia is a clinical syndrome of several causes, but with many symptoms and signs in common.