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Uhr L.; Clay Margaret; Platz A.; Miller J. G.; Kelley E. L. 《Canadian Metallurgical Quarterly》1961,63(3):546
The comparative effect of 2 tranquilizing drugs (miltown and thorazine) upon conditioning in normal adults was investigated. Conditioning involved GSR to a noxious (shock) and positive (sexually stimulating picture) stimulus. Both tranquilizers were observed to be ineffective in affecting classical conditioning procedures when the noxious UCS was used. Only miltown effected conditioning in the predicted direction when the positive UCS was used. The results are related to the differential effect of each tranquilizer upon the nervous system. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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de Oliveira Passos Marcelo Gonzalez Priscila Lujan Tessmann Mathias Schneid de Abreu Pereira Uhr Daniel 《Scientometrics》2022,127(10):5841-5862
Scientometrics - We use some modern scientometrics tools to detect which articles written in co-authorship are the most influential in the finance theory literature from 1896 to 2006. To develop a... 相似文献
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ES Vitetta TF Tucker E Racila YW Huang R Marches N Lane RH Scheuermann NE Street T Watanabe JW Uhr 《Canadian Metallurgical Quarterly》1997,89(12):4425-4436
The majority of BALB/c mice immunized with the BCL1 lymphoma-derived idiotype (Id+) IgM and subsequently challenged with BCL1 tumor cells develop a state of tumor dormancy. The vast majority of dormant lymphoma cells are in cell cycle arrest, but there are also residual replicating cells. In the present studies, we attempted to define features of both the dormant lymphoma cells and the host that lead to escape from dormancy. Escape from dormancy occurs at a steady rate over a 2-year period, suggesting that it is a stochastic process. We found that, in the majority of mice, escape was due to the emergence of genetic variants that were no longer susceptible to the anti-Id-mediated induction of dormancy. Ten percent of these variants were Id-; the remainder were Id+ but could grow in the presence of anti-Id antibodies, suggesting that there were mutations in molecules involved in one or more mIg-mediated negative-signaling pathways. In two of five such escapees, alterations in either Syk, HS1, and/or Lyn were observed. In a small percentage of mice, a low titer of circulating anti-Id antibody before tumor challenge correlated with a subsequent, more rapid loss of dormancy. 相似文献
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From the measurement of neck size and neck curvature during the sintering of two spheres the surface diffusion coefficients of MgO and Al2O3 were determined. The spheres of both materials were machined from single crystals. The following values of surface diffusion coefficients were found: for MgO,D
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s = 3.7 × 10–4 exp (407.8 kJ mol–1/RT m3 sec–1; for Al2O3,D
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s = 1.5 × 10–2 exp (518.7 kJ mol–1/RT) m3 sec–1. 相似文献