急性炎性疾病患者乳酸林格氏液液体动力学

目的:探索炎性疾病患者的乳酸林格氏液（Ringer's lactate,RL）液体动力学特征以及炎性生物标记物是否可以作为协变量影响RL分布和排泄。方法:本研究为前瞻性队列研究。选择40例美国麻醉医师分级（ASA）I-II级，腹腔镜下择期胆囊切除术（胆囊炎组，n=20）或者腹腔镜下急诊阑尾切除术（阑尾炎组，n=20）。所有患者麻醉诱导前开始输注RL，按15 mL/kg，35 min内输毕。采用酶联免疫（enzyme-linked immunosorbent assay,ELISA）方法测定血浆炎症（TNF-α,IL-10和CRP）或者内皮损伤生物标记物（syndecan-1,SDC-1）；利用血红蛋白（Hb）稀释-时间曲线和尿量，使用Phoenix软件，采用非线性混合效应模型分析计算RL液体动力学参数和协变量的影响。结果:与胆囊炎组相比，阑尾炎组RL从组织间隙到血浆的转运速率常数（k21）显著降低（14×10-3min-1 versus 35×10-3min-1;P=0.012）。阑尾炎组C反应蛋白（CRP）升高［中位数38.1(1.8-143.6) μg/mL versus 1.3(0.1-159.0) μg/mL;P<0.001］；与清醒状态相比，麻醉期间（输液开始后30～45 min），液体从中央室中到外周室的转运速率常数（k12）显著增加（57×10-3min-1 versus 32×10-3min-1；P<0.01）。清除速率常数（k10）降低90%（0.6×10-3min-1 versus 5.3×10-3min-1;P<0.001）。无论在清醒状态还是麻醉状态下低血压均能降低液体清除；炎症或者内膜损伤的生物标记物不能作为显著影响RL液体动力学参数的协变量。结论:阑尾炎或者胆囊炎患者术前输入液体后“炎症反应的生物标记物”不是RL的液体动力学的协变量，但是两组患者中，全身麻醉期间输入液体的清除率下降。     

上覆水磷浓度对沉积物孔隙水中磷垂向分布的影响

为探究上覆水磷浓度对沉积物孔隙水中磷垂向分布的影响,通过室内实验,利用薄膜扩散平衡技术(DET)对孔隙水中磷浓度进行测量,分析孔隙水磷浓度的垂向变化规律,并揭示平衡时上覆水磷浓度与孔隙水磷浓度以及上覆水-沉积物界面孔隙水磷浓度的关系。结果表明:上覆水磷浓度越高,则沉积物孔隙水中磷垂向分布达到平衡所需的时间越长,相同垂向位置处孔隙水磷浓度及其浓度梯度越大;孔隙水磷浓度及其浓度梯度随深度增加而降低,表层沉积物孔隙水中磷的扩散作用最强,下层沉积物孔隙水磷浓度受上覆水磷浓度变化影响较小;吸附平衡后,沉积物孔隙水磷浓度和上覆水-沉积物界面孔隙水磷浓度均与上覆水磷浓度呈幂函数关系,而留存在沉积物孔隙水中的磷浓度仅占2.26%～3.80%,上覆水中减少的磷大部分被沉积物吸附。     

Modeling and navigation of social information networks in metric spaces

We are living in a world of various kinds of social information networks with small-world and scale-free characteristics. It is still an intriguing problem for researchers to explain how and why so many obviously different networks emerge and share common intrinsic characteristics such as short diameter, higher cluster and power-law degree distribution. Most previous works studied the topology formation and information navigation of complex networks in separated models. In this paper, we propose a metric based range intersection model to explore the topology evolution and information navigation in a synthetic way. We model the network as a set of nodes in a distance metric space where each node has an ID and a range of neighbor information around its ID in the metric space. The range of a node can be seen as the local knowledge or information that the node has around its position in the metric space. The topology is formed by setting up a link between two nodes that have intersected ranges. Information navigation over the network is modeled as a greedy routing process using neighbor links and the distance metric. Different from previous models, we do not assume that nodes join the network one by one and set up link according to the degree distribution of existing nodes or distances between nodes. Range of node is the key factor determining the topology and navigation properties of a network. Moreover, as the ranges of nodes grow, the network evolves from a set of totally isolated nodes to a connected network. Thus, we can easily model the network evolutions in terms of the network size and the individual node information range using the range intersection model. A set of experiments shows that networks constructed using the range intersection model have the scale-free degree distribution, high cluster, short diameter, and high navigability properties that are owned by the real networks.     

Fe—Cr—Ni—Mo—C阀座材料的时效硬化及时效过程中的相转变

Fe-18.2Cr-6.9Ni-2.5Mo-1.5C材料铸态组成相为奥氏体和M7C_3型碳化物,在随后加热时可产生时效硬化现象,最佳时效温度为650℃。时效过程中可产生α-铁索体和M_23C_6型碳化物两个新相。     

Analysis and Implementation of an Open Programmable Router Based on Forwarding and Control Element Separation

A router architecture based upon ForCES (Forwarding and Control Element Separation), which is being standardized by IETF ForCES working group, gains its competitive advantage over traditional router architectures in flexibility, programmability, and cost-effectiveness. In this paper, design and implementation of a ForCES-based router (ForTER) is illustrated. Firstly, the implementation architecture of ForTER is discussed. Then, a layered software model, which well illustrates ForCES features, is proposed. Based on the model, design and implementation of Control Element (CE) and Forwarding Element (FE) in ForTER are introduced in detail. Moreover, security for ForTER is considered and an algorithm to prevent DoS attacks is presented. Lastly, experiments of ForTER are illustrated for routing and running routing protocols, network management, DoS attack prevention, etc. The experimental results show the feasibility of the ForTER design. Consequently, the ForTER implementation basically testifies the feasibility of ForCES architecture and some IETF ForCES specifications.     

Intensity standardization simplifies brain MR image segmentation

Typically, brain MR images present significant intensity variation across patients and scanners. Consequently, training a classifier on a set of images and using it subsequently for brain segmentation may yield poor results. Adaptive iterative methods usually need to be employed to account for the variations of the particular scan. These methods are complicated, difficult to implement and often involve significant computational costs. In this paper, a simple, non-iterative method is proposed for brain MR image segmentation. Two preprocessing techniques, namely intensity-inhomogeneity-correction, and more importantly MR image intensity standardization, used prior to segmentation, play a vital role in making the MR image intensities have a tissue-specific numeric meaning, which leads us to a very simple brain tissue segmentation strategy.Vectorial scale-based fuzzy connectedness and certain morphological operations are utilized first to generate the brain intracranial mask. The fuzzy membership value of each voxel within the intracranial mask for each brain tissue is then estimated. Finally, a maximum likelihood criterion with spatial constraints taken into account is utilized in classifying all voxels in the intracranial mask into different brain tissue groups. A set of inhomogeneity corrected and intensity standardized images is utilized as a training data set. We introduce two methods to estimate fuzzy membership values. In the first method, called SMG (for simple membership based on a gaussian model), the fuzzy membership value is estimated by fitting a multivariate Gaussian model to the intensity distribution of each brain tissue whose mean intensity vector and covariance matrix are estimated and fixed from the training data sets. The second method, called SMH (for simple membership based on a histogram), estimates fuzzy membership value directly via the intensity distribution of each brain tissue obtained from the training data sets. We present several studies to evaluate the performance of these two methods based on 10 clinical MR images of normal subjects and 10 clinical MR images of Multiple Sclerosis (MS) patients. A quantitative comparison indicates that both methods have overall better accuracy than the k-nearest neighbors (kNN) method, and have much better efficiency than the Finite Mixture (FM) model-based Expectation-Maximization (EM) method. Accuracy is similar for our methods and EM method for the normal subject data sets, but much better for our methods for the patient data sets.     

基于特勒根定理的风场送出线路新型纵联保护

双馈风机和永磁直驱风机广泛应用于陆上风电场。受控制策略影响,送出线路故障时风场侧故障特性与同步机电源差异显著,使传统纵联保护性能下降。特勒根定理建立于基尔霍夫电压、电流定律,仅与电路拓扑结构有关,对含线性/非线性、时变/时不变元件的电路均能适用。将特勒根定理应用到陆上风场送出系统,建立了满足定理应用要求的线路故障拓扑结构图。以此为基础,分析了能够区分内、外部故障的特征量,提出了一种基于故障前后线路两端电压电流的新型纵联保护动作判据。利用风场多个故障案例的录波数据和基于PSCAD的仿真数据对所提判据进行验证及对比分析,证明了所提纵联保护方法的优越性和可行性。     

可见光与红外图像融合质量评价指标分析

目的 客观评价作为图像融合的重要研究领域,是评价融合算法性能的有力工具。目前,已有几十种不同类型的评价指标,但各应用领域包括可见光与红外图像融合,仍缺少统一的选择依据。为了方便比较不同融合算法性能,提出一种客观评价指标的通用分析方法并应用于可见光与红外图像融合。方法 将可见光与红外图像基准数据集中的客观评价指标分为两类,分别是基于融合图像的评价指标与基于源图像和融合图像的评价指标。采用Kendall相关系数分析融合指标间的相关性,聚类得到指标分组;采用Borda计数排序法统计算法的综合排序,分析单一指标排序和综合排序的相关性,得到一致性较高的指标集合;采用离散系数分析指标均值随不同算法的波动程度,选择充分体现不同算法间差异的指标;综合相关性分析、一致性分析及离散系数分析,总结具有代表性的建议指标集合。结果 在13对彩色可见光与红外和8对灰度可见光与红外两组图像源中,分别统计分析不同图像融合算法的客观评价数据,得到可见光与红外图像融合的建议指标集(标准差、边缘保持度),作为融合算法性能评估的重要参考。相较于现有方法,实验覆盖20种融合算法和13种客观评价指标,并且不依赖主观评价结果。结论...     

校园网网络事件源定位技术研究

为了解决在校园网内部分网络安全事件和故障事件中只能确认攻击和事故的发生,而无法确定攻击和事故的源头这一问题.文章提出一种三步骤的校园网内网网络事件源定位模型.该模型将神经网络和证据理论相结合应用于攻击源定位.提高了校园网内网攻击定位的效率和准确性.