The effect of support morphology on the reaction of oxidative dehydrogenation of ethane to ethylene at short contact times

The oxidative dehydrogenation of ethane is carried out in short contact time reactors over Pt and LaMnO₃ based catalysts supported on a large number of different ceramic substrates (45, 60 and 80 ppi foam monoliths and 200, 400, 600, 900 and 1200 cpsi honeycomb monoliths). Experimental results, obtained under the same conditions at varying the C₂H₆/O₂ ratio, showed that the highest performance in terms of ethylene selectivity and yield is always attained on LaMnO₃ catalysts. Furthermore, the results are significantly influenced by the morphology and cell density of the support, with 45 and 60 ppi foams and 400 and 600 cpsi honeycombs giving the best performance. The experimental results are explained by means of geometrical and fluid dynamic considerations on the support, and by means of a 2D mathematical model, which clearly indicates an optimal intermediate cell density for maximising ethylene selectivity and yield.     

Necrotizing enterocolitis

Advances in neonatal care have resulted in an enlarging population of vulnerable premature newborns at risk for necrotizing enterocolitis (NEC). This article presents data supporting a unifying hypothesis for the initiation of NEC based on bacteria as the inciting agent(s), and the preterm baby as the vulnerable host. Facts and controversies concerning the pathology, microbiology, clinical presentation, management and outcome of infants afflicted with NEC are presented.     

Degradation of lincomycin in aqueous medium: Coupling of solar photocatalysis and membrane separation

The photocatalytic oxidation of a common antibiotic, the lincomycin was carried out in aqueous suspensions of polycrystalline TiO₂ Degussa P25 irradiated by sunlight. In order to improve the performance of the lincomycin degradation a hybrid system consisting of a solar photoreactor with the photocatalyst in suspension coupled with a membrane module, used to confine both photocatalyst and pollutants in the reaction environment, was tested.A preliminary study was carried out in order to determine some kinetics parameters of the drug photodegradation. The influence of initial substrate concentration on the lincomycin photooxidation rate was investigated. The photooxidation rate follows a pseudo-first order kinetics with respect to the lincomycin concentration under the used experimental conditions. The presence of the membrane reactor allows the catalyst separation and to operate in continuous mode as the membranes rejection for lincomycin and its oxidation products was quite high.     

Formation of cadmium-containing W-type hexagonal ferrite

The main steps of the phase formation processes which take place in samples of W-type hexaferrites containing cadmium, prepared by chemical coprecipitation, have been analysed. The processes were followed by Mössbauer spectroscopy, powder X-ray diffraction, thermomagnetic analysis and magnetic measurements. For samples heated in the temperature range 1000–1100°C, the phase formation processes are the same as those verified for the other zinc, nickel, cobalt W-type compounds: forT _h=1000°C the only phases present are SrFe₁₂O₁₉ (M-type ferrite) and CdFe₂O₄ (spinel ferrite); in contrast, forT _h>1100°C, the solid state reaction between the M-type and the spinel phases does not take place and the spinel phase decomposes, leading to the formation of -Fe₂O₃.     

Connexin 43 and Connexin 26 Involvement in the Ponatinib-Induced Cardiomyopathy: Sex-Related Differences in a Murine Model

Cardiac connexins (Cxs) are proteins responsible for proper heart function. They form gap junctions that mediate electrical and chemical signalling throughout the cardiac system, and thus enable a synchronized contraction. Connexins can also individually participate in many signal transduction pathways, interacting with intracellular proteins at various cellular compartments. Altered connexin expression and localization have been described in diseased myocardium and the aim of this study is to assess the involvement of Cx43, Cx26, and some related molecules in ponatinib-induced cardiac toxicity. Ponatinib is a new multi-tyrosine kinase inhibitor that has been successfully used against human malignancies, but its cardiotoxicity remains worrisome. Therefore, understanding its signaling mechanism is important to adopt potential anti cardiac damage strategies. Our experiments were performed on hearts from male and female mice treated with ponatinib and with ponatinib plus siRNA-Notch1 by using immunofluorescence, Western blotting, and proteomic analyses. The altered cardiac function and the change in Cxs expression observed in mice after ponatinib treatment, were results dependent on the Notch1 pathway and sex. Females showed a lower susceptibility to ponatinib than males. The downmodulation of cardiac Cx43, Cx26 and miR-122, high pS368-Cx43 phosphorylation, cell viability and survival activation could represent some of the female adaptative/compensatory reactions to ponatinib cardiotoxicity.     

Sublattice magnetization and cation distribution in BaMg2Fe16O27(Mg2W) ferrite

Mössbauer measurements were carried out in compound BaMg2Fe16O27(Mg2W) by utilizing both polycrystalline and single-crystal samples. The resonant γ-absorption spectra have been measured with the absorbers at temperatures of 85 to 800°K and in some cases in the presence of a 15-kOe external magnetic field. The values of the hyperfine magnetic fields Hhfat the Fe⁵⁷nuclei in the different sublattices as functions of temperature have been measured. By fitting the curve of the saturation magnetization σ versus temperature, the cation distribution over the available lattice sites has been deduced. From the value of σ extrapolated at 0°K, it turns out that the number of Bohr magnetons(n_{B})Wper elementary cell is higher than the value obtained by adding the corresponding values for theSandMstructures. The Curie temperature of the compounds has also been measured and is equal to (440 ± 5)°C.     

Efficient application identification and the temporal and spatial stability of classification schema

Motivated by the importance of accurate identification for a range of applications, this paper compares and contrasts the effective and efficient classification of network-based applications using behavioral observations of network-traffic and those using deep-packet inspection.Importantly, throughout our work we are able to make comparison with data possessing an accurate, independently determined ground-truth that describes the actual applications causing the network-traffic observed.In a unique study in both the spatial-domain: comparing across different network-locations and in the temporal-domain: comparing across a number of years of data, we illustrate the decay in classification accuracy across a range of application–classification mechanisms. Further, we document the accuracy of spatial classification without training data possessing spatial diversity.Finally, we illustrate the classification of UDP traffic. We use the same classification approach for both stateful flows (TCP) and stateless flows based upon UDP. Importantly, we demonstrate high levels of accuracy: greater than 92% for the worst circumstance regardless of the application.     

The influence of attentional engagement and spatial characteristics on time perception in virtual reality

Virtual Reality - Virtual reality (VR) is a simulation tool that is being used extensively to study the effects of training and perception. However, several studies have shown that some aspects of...     

Botulinum toxin injections in the internal anal sphincter for the treatment of chronic anal fissure: long-term results after two different dosage regimens

OBJECTIVE: To determine whether the recently published guidelines on neuroimaging in patients with new-onset seizures are applicable to children. METHODS: We carried out a retrospective analysis of 107 neurologically normal children (excluding children with simple febrile seizures) who had undergone neuroimaging when they presented to the emergency department with a possible "first seizure." RESULTS: Eight of the 107 children had nonepileptic events (gastroesophageal reflux, syncopal event, rigor). Of the remaining 99 children, 49 had provoked seizures (complicated febrile seizure, meningo-encephalitis, toxic or metabolic abnormalities), and 50 had unprovoked seizures. A total of 19 children had brain abnormalities identified on computed tomography (CT) scan; 7 received further investigation or intervention as a result of CT scan findings (2 with tumors, 3 with vascular anomalies, 1 with cysticercosis, and 1 with obstructive hydrocephalus). CT scan abnormalities requiring treatment or monitoring were more frequently seen in children with their first unprovoked seizure (P < .01) and in those children whose seizure onset had been focal or who had focal abnormalities identified on postictal neurologic examination (P < .04). CONCLUSION: In a child, a seizure in the setting of a fever rarely indicates the presence of an unexpected CT scan lesion requiring intervention.