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1.
Design science in information systems research   总被引:1,自引:1,他引:0  
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2.
Traditional auction mechanisms support price negotiations on a single item. The Internet allows for the exchange of much more complex offers in real-time. This is one of the reasons for much research on multidimensional auction mechanisms allowing negotiations on multiple items, multiple units, or multiple attributes of an item, as they can be regularly found in procurement. Combinatorial auctions, for example, enable suppliers to submit bids on bundles of items. A number of laboratory experiments has shown high allocative efficiency in markets with economies of scope. For suppliers it is easier to express cost savings due to bundling (e. g., decreased transportation or production costs). This can lead to significant savings in total cost of the procurement manager. Procurement negotiations exhibit a number of particularities:
  • It is often necessary to consider qualitative attributes or volume discounts in bundle bids. These complex bid types have not been sufficiently analyzed.
  • The winner determination problem requires the consideration of a number of additional business constraints, such as limits on the spend on a particular supplier or the number of suppliers.
  • Iterative combinatorial auctions have a number of advantages in practical applications, but they also lead to new problems in the determination of ask prices.
  • In this paper, we will discuss fundamental problems in the design of combinatorial auctions and the particularities of procurement applications. Reprint of an article from WIRTSCHAFTSINFORMATIK 47(2)2005:126–134.  相似文献   
    3.
    Zirconia (ZrO2) ceramics are being considered as a candidate material for thermal insulating barriers in pressure tubes used in the supercritical water (SCW) nuclear reactors. However, the literature suggests that zirconia may undergo a detrimental phase transformation which is accelerated in aqueous environments. In this research, 8 mol% Yttria-Stabilized Zirconia (YSZ) ceramics with the addition of 5 and 10 mol% Nd2O3 were manufactured via spark plasma sintering (SPS) process and subsequently subjected to a SCW environment. The weight losses and microstructural evolutions of these materials during SCW exposure were studied. The results suggest that doping YSZ with Nd2O3 significantly decreased the degradation rate of the YSZ ceramic and improved its structural stability. X-ray diffraction studies revealed that after degradation testing, the Nd2O3 helped to retain the desirable cubic phase of YSZ matrix. In the case of pure YSZ ceramic, a phase change of the matrix toward the monoclinic lattice was observed and likely contributed to the ceramic’s disintegration in SCW environment.  相似文献   
    4.
    IT service providers are increasingly hosting different services of different customers on a shared IT infrastructure. While this fosters utilization of hardware infrastructure, system malfunctions, unexpected service behaviour or peak demands for one or more services may exploit resource pools (CPU, I/O, main memory, bandwidth etc.), entailing rejection of service requests. In this paper we describe models for dynamic admission control on shared infrastructures. The admission control model decides whether to accept, buffer or reject a service request based on the revenue, Service Level Agreements (SLAs) and its resource demand in comparison to the actual workload to maximize overall revenue. Simulations of a media streaming infrastructure have been used for evaluation and comparison with traditional admission control policies.  相似文献   
    5.
    Object-oriented (OO) modeling languages, tools, and methods more and more attract the interest of embedded (real-time) system developers. This is especially true if embedded (real-time) system software has to cooperate with interactive multimedia software, as it is more and more the case in automotive systems. It is still an open question whether and how the standard OO modeling language UML and its accompanying tools have to be adapted to the regarded application domain. This paper evaluates the development of a rapid prototype for an air condition controller with the popular CASE tool Rational Rose/RT®. We point out some weaknesses of the presented solution and propose an extension to Rose/RT®, which overcomes the weaknesses by combining Rose/RTs UML dialect with data flow equations.  相似文献   
    6.
    IT infrastructure, such as servers and networking equipment, accounts for a large proportion of the IT costs in modern organizations. Typically, this IT infrastructure is shared among multiple applications and customers. Cost allocation of shared IT infrastructure is difficult and regularly based on biased cost allocation keys, which often causes free-rider problems. Measuring usage is technically difficult and incurs high costs. In this paper we propose a method to derive adequate estimators for the resource consumption of a customer-oriented service. These so-called resource profiles can then provide a basis for cost allocation keys. The estimators are derived from a series of load tests, as they are typically done before an application is launched in larger organizations. Such profiles need to be unbiased and precise even in cases of varying workloads and in rather heterogeneous environments. We describe the results of a set of experiments in an infrastructure provided by the BMW Group, and illustrate how the estimation can be integrated into existing IT service management processes. In our experiments we use Queuing Networks to validate the estimated resource profiles under different workloads.  相似文献   
    7.
    8.
    Gas mantles for camping gas lanterns sometimes contain thorium compounds. During the last years, the use of thorium-free gas mantles has become more and more popular due to the avoidance of a radioactive heavy metal. We investigated a gas mantle type that is declared to be "non-radioactive" and that can be bought in Austria at the moment. Methods used were Instrumental Neutron Activation Analysis (INAA), gamma-spectroscopy, and Liquid Scintillation Counting (LSC). We found massive thorium contents of up to 259 mg per gas mantle. Leaching experiments showed that only 0.4% of the Th but approximately 90% of the decay products of (232)Th can be leached under conditions simulating sucking and chewing with human saliva. In this paper, the investigation of these gas mantles including the consideration of the environmental hazard caused by disposed mantles and the health hazard for unsuspecting consumers is presented and legal consequences are discussed for this fraud.  相似文献   
    9.
    10.
    BACKGROUND: The degree to which antithrombotic drugs suppress thrombin generation is unknown. Because hirudin, unlike antithrombin III, binds intravascular thrombin rapidly and selectively to yield a circulating inactive complex of 3- to 4-hour half-life, we used intravenous hirudin in humans to investigate the course of thrombin generation during and early after anticoagulation with this potent, direct antithrombin. METHODS AND RESULTS: Intravascular thrombin was measured with an ELISA for the thrombin-hirudin complex formed during and for 18 hours after stopping a 6-hour infusion of hirudin at 0.1, 0.2, and 0.3 mg.kg-1.h-1 in three groups of six patients each. With free hirudin in 20- to 10,000-fold molar excess of thrombin and peak activated partial thromboplastin times of 2.3 to 3.0 times baseline, mean plasma thrombin-hirudin complex increased from 794 +/- 85 pg/mL (mean +/- SEM) 15 minutes after the start of the infusion to 1617 +/- 151 pg/mL at 6 hours of infusion to 2667 +/- 654 pg/mL at 24 hours. During the 24-hour observation period, plasma concentration of fragment 1.2 (the peptide released during conversion of prothrombin to thrombin) never fell below baseline but rather increased transiently during the hirudin infusion. Plasma concentrations of thrombin-antithrombin III complex (in ng/mL) decreased from 4.34 +/- 0.40 at baseline to 1.64 +/- 0.13 at 6 hours (P < .001) and gradually increased after stopping the infusion to 5.7 +/- 0.87 at 24 hours (nonsignificant compared with baseline). CONCLUSIONS: Measurement of thrombin-hirudin complex may be used as a marker of thrombin generation in humans. Persistent accumulation of thrombin-hirudin complex and generation of fragment 1.2 during and after completion of potent anticoagulation with hirudin suggest thrombin generation is not blocked by high-affinity thrombin inhibition. The persistent formation of thrombin during declining plasma levels of hirudin may contribute to the pathogenesis of rethrombosis early after antithrombin therapy or during inadequate anticoagulation.  相似文献   
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