游戏音乐：策划应该做什么？

游戏是类似电影的多媒体娱乐产品。好的配乐、录音对于电影的最终效果有极大的影响．相对的游戏音乐对于游戏气氛的烘托也占有举足轻重的地位。虽然目前音乐在游戏中所占的比重还较小，原因一方面是游戏类型比较多样．对音乐的要求不尽相同：另一方面．大部分游戏不需要极度拟真或是戏剧化的效果．所以游戏音乐相比游戏模式而言被摆在了一个比较次要的位置．但如果你想制作一个尽善尽美的游戏或者锦上添花．就不能不在游戏音乐上花费心思。要知道．优秀游戏音乐的诞生不仅有赖于音频制作人员的努力．游戏策划的幕后工作也非常重要．下面笔者与大家探讨策划在游戏音乐的工作中总结出来的一些经验心得。     

Dorsal mesencephalic lipoma with inferior collicular hypoplasia: a case report and review of literature

Integrins are a superfamily of cell surface receptors involved in cell-cell and cell-matrix adhesion. Integrin-mediated interactions are involved in the regulation of numerous cellular functions such as fertilization, implantation, cell differentiation and migration during embryonic development, maintaining tissue architecture, blood clot formation and retraction programmed cell death, tumor growth and metastasis formation, lymphocyte homing and response of cells to mechanical stresses. This broad spectrum of activity is achieved by combining the ability to create mechanically functional junctions (cell-matrix and cell-cell) and signal-transducing capabilities. Osteoblasts and osteoclasts express specific integrin receptors and the pattern of expression varies depending on the stage of cell differentiation. Interactions of integrins with bone-matrix adhesive proteins are thought to be important for regulating the tissue integrity and may provide a local, responsive regulatory system of osteoblastic differentiation as well. Osteoclasts most likely attach to osteopontin exposed on the bone surface via the classic vitronectin receptor alpha v beta 3 and this binding may be crucial to their bone resorption activity.