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With greater need for treating root surface lesions, dentinal adhesives are more in demand. For successful treatment, all factors--dentin, tooth, patient and materials--must be considered. 相似文献
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An extensive and systematic search strategy to determine the conformational profile of 12 cyclic disulfide-bridged opioid peptides with varying affinities at the delta receptor has been carried out to identify the structure that is recognized by the delta receptor for each analogue. The methods and procedures used here for the conformational search have already been validated for [D-Pen2,D-Pen5] enkephalin (DPDPE), one member of this family. Use of these methods led to a low-energy solution conformation of DPDPE in excellent agreement with all the geometric properties deduced from its solution nmr spectra. Each of the analogue was subjected to the same procedure, involving a combination of molecular dynamics simulations at high and low temperature. The study was repeated in two environmental conditions, an apolar environment, simulated by using a distance-dependent dielectric constant, and a polar environment by embedding the peptides in a high constant dielectric (epsilon = 80). An automated comparison of the different conformers based on their backbone rms and average distance between the key aromatic moieties was followed by graphic analysis using maximum structural overlap. The cross-comparison of the conformations for each analogue revealed a unique conformer that may be recognized by the delta receptor for each high-affinity analogue that permitted maintaining the critical elements required for recognition in a simple spatial orientation, while maximizing similarity in other regions. 相似文献
4.
模板的安全性和隐私性是掌纹系统实际应用的关键问题,然而生物特征保护的多项指标通常相互冲突并且难以同时满足.作为解决上述冲突的一种可撤销掌纹编码算法,PalmPhasor实现了高效、安全的掌纹认证.建立了系统分析PalmPhasor性能的完整框架.为了便于具体分析,将情景分为4种情况,并且提供了支持相应分析的预备知识,包括辅助定理以及Gabor滤波掌纹图像实部和虚部分布特性.在统计学基础上建立的理论分析和实验结果均表明:即使在用户口令被盗的情况下,多方向分数级融合增强的PalmPhasor算法也可以同时有效地满足可撤销生物特征的4项指标. 相似文献
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HO Klein 《Canadian Metallurgical Quarterly》1976,69(3):441-444
Ventricular premature beats (VPBs) appeared in a patient after pacemaker insertion for complete heart block secondary to acute myocardial infarction. Contrary to expectations, the frequency of VPBs was directly related to the basic pacemaker rate. The VPBs are either reentrant beats or represent VPBs arising from pacemaker cells with "slow-response" characteristics, which have been shown to become more automatic with increasing rates of electrical stimulation. This case documents the phenomenon of rate dependency of VPBs in man and discusses its practical importance. 相似文献
7.
Shop-floor scheduling at shipbuilding yards using the multiple intelligent agent system 总被引:4,自引:0,他引:4
The intelligent agent system has become a typical approach to research distributed artificial intelligence and distributed problem solving. However, despite its various technical advantages, the distribution and expansion of the intelligent agent system approach has been limited because existing methodologies rely on specialized applications and therefore require intensive investment to develop new systems. In an attempt to conquer these difficulties, a standardized methodology to construct intelligent agent systems is proposed. This approach deviates from current agent system approaches of repeatedly constructing new and customized expert systems. Specifically, it provides an economical method for developing intelligent agent systems by investigating the possibility of standardizing message communication protocols in linguistics speech-act theory and by supplementing traditional algorithmic systems with intelligent segments using, among others, expert system tools. To verify effectiveness, the shop-floor scheduling system of a large-scale shipbuilding yard has been redesigned, developed, and tested using this approach. This shop-floor scheduling system requires the scheduling of when and where to process block construction under various constraints. It is a difficult four-dimensional time and space allocation problem involving traditional NP-complete search spaces. The tested intelligent agent system proposes an innovative method for reducing the search space into three levels: the algorithm level, the agent intelligence level, and the level of cooperation among agents. It also provides methods for solving deadlock occurrence and non-uniformity problems resulting from parallel processing. Test results demonstrate applicability and economy, among other technical advantages. 相似文献
8.
We investigated the effect of aligning crystal orientation in the microstructures containing sub micro-sized grains on the thermoelectric properties for polycrystalline Bi-Te materials.Bi-Te powder,prepared through the conventional pulverization process,was sufficiently dispersed in an appropriate solvent,and then was formed into c-axis aligned green bodies under a designated high magnetic field.The green bodies were sintered with spark-plasma-sintering machine.The degree of crystal alignment of sintered bodies was examined with the electron-back-scatter-diffraction SEM and the X-ray diffraction patterns.It was observed that for both p and n type thermoelectric Bi-Te materials,aligning crystal orientation properly made electrical resistivity decreased with keeping Seebeck coefficient and thermal conductivity remained unchanged.As a typical result,the aligned Bi-Te material with the magnetic field of 10 tesla showed 30%enhancement of the thermoelectric performance. 相似文献
9.
A new controller for linear multivariable ordinary systems is suggested in which distributed delays are included in the feedback loop. A general design approach to obtain this type of controller is suggested. It is shown that the resulting closed-loop system is asymptotically stable under some sufficient conditions. Sufficient conditions are derived under which the disturbance attenuation, the robustness against parameter variations, and the time-delay stability margins are improved by the proposed controller. The state feedback tracking controller and the dual-state observer are obtained by modification of the proposed controller. 相似文献
10.
Sweet potato and corn starches were gelatinized and liquefied to dextrose equivalent (DE) 10 in a steam-jacketed kettle or in a twin-screw extrusion cooker in a single step process with a heat stable ex-amylase. The time required to gelatinize and liquefy 20% starch slurries in a kettle at 95°C was 45 to 50 sec. Starch powder (10 kg/hr) and water (2-6 kg/hr) were fed to an extrusion cooker to adjust the moisture contents of the starch from 20 to 55% (wet basis) and gelatinized and liquefied to DE 10 at a barrel temperature of 120°C or above with 2 to 3% (w/w) a-amylase added. The optimum conditions for the operation were to feed starch with water to maintain 50% moisture and 2% heat stable a-amylase at a barrel temperature of 120°C. 相似文献