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排序方式: 共有79条查询结果,搜索用时 15 毫秒
1.
A. Campillo J. I. Farran M. J. Pisabarro 《Applicable Algebra in Engineering, Communication and Computing》2007,18(1-2):191-203
We use the special geometry of singular points of algebraic differential equations on the affine plane over finite fields
to study the main features and parameters of error correcting codes giving by evaluating functions at sets of singular points.
In particular, one gets new methods to construct codes with designed minimum distance.
This work was partially supported by MCyT BFM2001-2251. 相似文献
2.
Campillo Mauricio Sedaghati Ramin Drew Robin A. L. Alfonso Ismeli Prez Luis 《Engineering with Computers》2021,38(3):1767-1785
Engineering with Computers - In this article, a methodology based on Discrete Element Method (DEM) and Finite Elements Method (FEM) combined with modified Approximate Periodic Boundary Condition... 相似文献
3.
María A. Vasco-Mogorrn Jos A. Campillo Adela Periago Valentin Cabaas Mercedes Berenguer María C. García-Garay Lourdes Gimeno María F. Soto-Ramírez María D. Martínez-Hernndez Manuel Muro Alfredo Minguela 《International journal of molecular sciences》2021,22(8)
Proliferation and apoptosis of neoplastic cells are prognostic biomarkers in plasma cell neoplasms (PCNs). The prognostic capacity of proliferation to apoptosis ratio (Ratio-PA) in the era of immunomodulatory treatments is re-evaluated in 316 gammopathy of undetermined significance (MGUS), 57 smoldering multiple myeloma (SMM), and 266 multiple myeloma (MM) patients. Ratio-PA of 0.77 ± 0.12, 1.94 ± 0.52, and 11.2 ± 0.7 (p < 0.0001) were observed in MGUS, SMM, and MM patients. Ten-year overall survival (10y-OS) rates for patients with low/high Ratio-PA were 93.5%/77.3% p < 0.0001) for MGUS, 82.5%/64.7% (p < 0.05) for SMM, and 62.3%/47.0% (p < 0.05) for MM. For patients with low, intermediate, and high risk, 10y-OS for low/high Ratio-PA were 95.5%/72.9% (p < 0.0001), 74.2%/50.4% (p < 0.0001), and 35.3%/20.0% (p = 0.836), respectively. Ratio-PA was an independent prognostic factor for OS (HR = 2.119, p < 0.0001, Harrell-C-statistic = 0.7440 ± 0.0194) when co-analyzed with sex, age, and standard risk. In patients with Ratio-PAhigh, only first-line therapy with VRd/VTd, but not PAD/VCD, coupled with ASCT was associated with high 10y-OS (82.7%). Tumor cell Ratio-PA estimated at diagnosis offers a prognostic biomarker that complements standard risk stratification and helps to guide the clinical management of pre-malignant and symptomatic PCNs. Every effort should be made to provide first-line therapies including VTd or VRd associated with ASCT to patients with Ratio-PAhigh at higher risk of progression and death. 相似文献
4.
Alfredo Jurez-Saldivar Elizabeth Barbosa-Cabrera Edgar E. Lara-Ramírez Alma D. Paz-Gonzlez Ana V. Martínez-Vzquez Virgilio Bocanegra-García Isidro Palos Nuria E. Campillo Gildardo Rivera 《International journal of molecular sciences》2021,22(11)
Infectious diseases caused by intestinal protozoan, such as Entamoeba histolytica (E. histolytica) and Giardia lamblia (G. lamblia) are a worldwide public health issue. They affect more than 70 million people every year. They colonize intestines causing primarily diarrhea; nevertheless, these infections can lead to more serious complications. The treatment of choice, metronidazole, is in doubt due to adverse effects and resistance. Therefore, there is a need for new compounds against these parasites. In this work, a structure-based virtual screening of FDA-approved drugs was performed to identify compounds with antiprotozoal activity. The glycolytic enzyme triosephosphate isomerase, present in both E. histolytica and G. lamblia, was used as the drug target. The compounds with the best average docking score on both structures were selected for the in vitro evaluation. Three compounds, chlorhexidine, tolcapone, and imatinib, were capable of inhibit growth on G. lamblia trophozoites (0.05–4.935 μg/mL), while folic acid showed activity against E. histolytica (0.186 μg/mL) and G. lamblia (5.342 μg/mL). 相似文献
5.
A. Serrano Aroca A.J. Campillo Fernndez J.L. Gmez Ribelles M. Monlen Pradas G. Gallego Ferrer P. Pissis 《Polymer》2004,45(26):8949-8955
Dynamic-mechanical and water sorption properties of porous and non-porous hydrogels have been studied as a function of their porosity and crosslinking density. Porous hydrogels with different crosslinking densities were prepared by co-polymerisation of 2-hydroxyethyl acrylate and ethyleneglycol dimethacrylate in solution in methanol. Pores were formed due to the segregation of the solvent from the polymer network during the polymerisation process. The porosity of the samples was observed by scanning electron microscopy. The pores collapse during the drying process after polymerisation but they reopen when the xerogel is immersed in liquid water. Bulk polymer networks with varying crosslinking densities were also synthesised and used as a reference in the analysis of the porous hydrogels. Water sorption from the gas phase and from the liquid phase was studied by means of equilibrium sorption isotherms and immersion experiments, respectively. Dynamic-mechanical spectroscopy conducted on the xerogels shows that the elastic modulus in the rubber-like state highly depends on the amount of solvent used in the polymerisation what is attributed to the presence of discontinuity surfaces in the xerogel although the pores are closed. 相似文献
6.
B. Campillo C. Rodriguez J. Genesca J. Juarez-lslas . Flores L Martinez 《Journal of Materials Engineering and Performance》1997,6(4):449-453
Commercial magnesium anodes were evaluated using ASTM G 97-89 for a standard test along with a technique of electrochemical
impedance. Several heat treatments were performed, and the anodic efficiency was determined, showing an incremental increase
of 10 to 12 % of the efficiency demonstrated by the nontreated commercial anodes (as-cast condition). The increase in efficiency
was related to the microstructural characteristics. The appearance of second phase particles influenced the form of the corrosion
process. 相似文献
7.
8.
Clément C. Campillo André P. Schroder Carlos M. Marques Brigitte Pépin-Donat 《Materials science & engineering. C, Materials for biological applications》2009,29(2):393-397
We further investigate the properties of composite Poly(NIPAM) (poly(N-isopropylacrylamide)) gel-filled giant vesicles, focusing here on i) the homogeneity of the membrane, ii) its coupling to the inner gel under strong suction pressures, and iii) the relation between the final elastic modulus of the vesicles and the amount of crosslinker in the pre-gel medium. We show that whereas the photo-polymerization process induces a decrease of the membrane homogeneity at the micrometer size range, the membrane still remains strongly coupled to the internal gel network. The vesicles studied here display average moduli in the range [0.5–25] kPa, confirming their potential as biomimetic mechanical systems. 相似文献
9.
10.
In this letter, the behavior of a recently reported left-handed metamaterial working at millimeter-wave frequencies is analyzed. The metamaterial is built by the periodic stacking of metallic plates with sub-wavelength hole arrays that show extraordinary optical transmission. If the longitudinal period of the stacked structure is chosen adequately, it is possible to mold the electromagnetic wave propagation inside the structure from right-handed to left-handed. The transmission response of the fabricated prototype has been measured with a millimeter wave quasioptical vector network analyzer in the range between 40 GHz and 110 GHz confirming the possibility to tune the left-handed or right handed characteristics of the waves propagating there. These results can give rise to interesting applications such as novel lenses and other quasioptical structures 相似文献