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The Journal of Supercomputing - Infrastructure-as-a-service container-based virtualization is gaining interest as a platform for running distributed applications. With increasing scale of cloud... 相似文献
3.
Kazuo Tsubota Stephen C. Pflugfelder Zuguo Liu Christophe Baudouin Hyo Myung Kim Elisabeth M. Messmer Friedrich Kruse Lingyi Liang Jimena Tatiana Carreno-Galeano Maurizio Rolando Norihiko Yokoi Shigeru Kinoshita Reza Dana 《International journal of molecular sciences》2020,21(23)
Over the past decades, the number of patients with dry eye disease (DED) has increased dramatically. The incidence of DED is higher in Asia than in Europe and North America, suggesting the involvement of cultural or racial factors in DED etiology. Although many definitions of DED have been used, discrepancies exist between the various definitions of dry eye disease (DED) used across the globe. This article presents a clinical consensus on the definition of DED, as formulated in four meetings with global DED experts. The proposed new definition is as follows: “Dry eye is a multifactorial disease characterized by a persistently unstable and/or deficient tear film (TF) causing discomfort and/or visual impairment, accompanied by variable degrees of ocular surface epitheliopathy, inflammation and neurosensory abnormalities.” The key criteria for the diagnosis of DED are unstable TF, inflammation, ocular discomfort and visual impairment. This definition also recommends the assessment of ocular surface epitheliopathy and neurosensory abnormalities in each patient with suspected DED. It is easily applicable in clinical practice and should help practitioners diagnose DED consistently. This consensus definition of DED should also help to guide research and clinical trials that, to date, have been hampered by the lack of an established surrogate endpoint. 相似文献
4.
Isaac Isarn Leïla Bonnaud Lluís Massagus ngels Serra Francesc Ferrando 《Polymer International》2020,69(3):280-290
The enhancement of the thermal conductivity, keeping the electrical insulation, of epoxy thermosets through the addition of pristine and oxidized carbon nanotubes (CNTs) and microplatelets of boron nitride (BN) was studied. Two different epoxy resins were selected: a cycloaliphatic (ECC) epoxy resin and a glycidylic (DGEBA) epoxy resin. The characteristics of the composites prepared were evaluated and compared in terms of thermal, thermomechanical, rheological and electrical properties. Two different dispersion methods were used in the addition of pristine and oxidized CNTs depending on the type of epoxy resin used. Slight changes in the kinetics of the curing reaction were observed in the presence of the fillers. The addition of pristine CNTs led to a greater enhancement of the mechanical properties of the ECC composite whereas the oxidized CNTs presented a greater effect in the DGEBA matrix. The addition of CNTs alone led to a marked decrease of the electrical resistivity of the composites. Nevertheless, in the presence of BN, which is an electrically insulating material, it was possible to increase the proportion of pristine CNTs to 0.25 wt% in the formulation without deterioration of the electrical resistivity. A small but significant synergic effect was determined when both fillers were added together. Improvements of about 750% and 400% in thermal conductivity were obtained in comparison to the neat epoxy matrix for the ECC and DGEBA composites, respectively. © 2019 Society of Chemical Industry 相似文献
5.
A Lattice Approach to Image Segmentation 总被引:1,自引:0,他引:1
Jean Serra 《Journal of Mathematical Imaging and Vision》2006,24(1):83-130
After a formal definition of segmentation as the largest partition of the space according to a criterion σ and a function
f, the notion of a morphological connection is reminded. It is used as an input to a central theorem of the paper (Theorem
8), that identifies segmentation with the connections that are based on connective criteria. Just as connections, the segmentations can then
be regrouped by suprema and infima. The generality of the theorem makes it valid for functions from any space to any other
one. Two propositions make precise the AND and OR combinations of connective criteria.
The soundness of the approach is demonstrated by listing a series of segmentation techniques. One considers first the cases
when the segmentation under study does not involve initial seeds. Various modes of regularity are discussed, which all derive
from Lipschitz functions. A second category of examples involves the presence of seeds around which the partition of the space
is organized. An overall proposition shows that these examples are a matter for the central theorem. Watershed and jump connection
based segmentations illustrate this type of situation. The third and last category of examples deals with cases when the segmentation
occurs in an indirect space, such as an histogram, and is then projected back on the actual space under study.
The relationships between filtering and segmentation are then investigated. A theoretical chapter introduces and studies the
two notions of a pulse opening and of a connected operator. The conditions under which a family of pulse openings can yield a connected filter are clarified. The ability of segmentations
to generate pyramids, or hierarchies, is analyzed. A distinction is made between weak hierarchies where the partitions increase
when going up in the pyramid, and the strong hierarchies where the various levels are structured as semi-groups, and particularly
as granulometric semi-groups.
The last section is based on one example, and goes back over the controversy about “lattice” versus “functional” optimization.
The problem is now tackled via a case of colour segmentation, where the saturation serves as a cursor between luminance and
hue. The emphasis is put on the difficulty of grouping the various necessary optimizations into a single one. 相似文献
6.
7.
Anamaria Martins Christophe Ringeissen Anderson Santana 《Electronic Notes in Theoretical Computer Science》2003,86(2):77
The adaptation of software components developed for a specific application in order to generate reusable components often includes some kind of generalization. This generalization may be carried out, for instance, by the renaming of some identifiers or by its parameterization. In our work, we are specially interested in the generalization by parameterization of algebraic specification components. Generalization and some other transformations on algebraic specifications are being integrated in the FERUS tool. This tool was initially developed for the Common Algebraic Specification Language, called CASL, and we show in the paper its adaptation to the new version of the rule-based programming language ELAN. 相似文献
8.
F Licastro M Chiricolo MC Morini I Capri LJ Davis R Conte R Mancini C Melotti R Parente R Serra 《Canadian Metallurgical Quarterly》1995,41(4):235-241
Apparently healthy elderly donors were screened according to a simple protocol that included clinical examination and the determination of hematological and biochemical values. This screening was performed to detect subclinical alterations which might interfere with immune responses and trace element status. The elderly were divided into two groups. The first group consisted of 22 (age 76 +/- 1 years) positively selected elderly (PSE), i.e. healthy subjects with no hematological and laboratory alterations, the second one comprised 13 (age 75 +/- 1 years) negatively selected elderly (NSE). Data were then compared with those obtained from 40 (age 35 +/- 2 years) healthy young controls. In both groups of elderly donors, plasma zinc levels were normal, while plasma copper concentrations were increased. Intracellular values of zinc and copper in mono- and polymorphonuclear cells from both groups of elderly were within reference limits. After in vitro activation, granulocyte chemiluminescence activity was impaired only in NSE. A decrement in the number of circulating CD3 lymphocytes and an increase in CD8d, CD57 cells were found in PSE, while NSE showed an increased number of CD3,DR cells and CD8d, CD57, CD8b,CD57 and CD16,CD56 positive cells. Our results indicate that only plasma copper levels were affected by age, whereas subclinical alterations in hematological or biochemical values appear to impair immune responses in the elderly. 相似文献
9.
The Use of Biopreservatives in the Control of Bacterial Contaminants of Sugarcane Alcohol Fermentation 总被引:1,自引:0,他引:1
ABSTRACT: Efficacy and safety of biopreservatives were studied for microbiological control of alcohol fermentation. Minimum inhibitory concentrations of nisin and lysozyme, and combinations with EDTA and Tween 20, were determined for Lactobacillus plantarum, L. fermentum , and L. confusus. The highest MIC value for nisin was 9.0 ppm for L. fermentum. Lysozyme was efficient against L. plantarum (700 ppm). A 24 factorial design was used to study the effect of biopreservatives and potentiators on the growth kinetics of Lactobacillus fermentum. The combination of 8.6 ppm of nisin plus 0.1% of Tween 20 delayed the lag phase by 12 h. The biopreservatives did not affect the fermentation kinetics of Saccharomyces cerevisiae. 相似文献
10.
The equivalent inclusion method (EIM) assuming linear elasticity is used to calculate the mechanical interactions between spherical rubber particles in an amorphous matrix, as in a rubber toughened polymer. The influences of the various calculation parameters are examined and it is shown that the method can provide reliable results with regard to the level of hydrostatic stress in the particles. Damage of the material is simulated by replacing the most stressed particles by voids. Numerical simulations for several hundreds of interacting particles give information on the kinetics and spatial organisation of the damage. It appears that, as the volume fraction of particles increases from 10 to 20%, the spatial configuration of the damage evolves from a localised to a diffuse mode. These results are discussed in relation to the efficiency of rubber toughening. 相似文献