A Survey on Advanced Multiple Access Techniques for 5G and Beyond Wireless Communications

Wireless Personal Communications - This paper summarizes the ongoing research initiatives based on the advanced multiple access techniques towards the fifth generation (5G) wireless communication...     

A matching game framework for users clustering and resource allocation with wireless power transfer in a CR-NOMA network

This paper investigates the resource allocation in a massively deployed user cognitive radio enabled non-orthogonal multiple access (CR-NOMA) network considering the downlink scenario. The system performance deteriorates with the number of users who are experiencing similar channel characteristics from the base station (BS) in NOMA. To address this challenge, we propose a framework for maximizing the system throughput that is based on one-to-one matching game theory integrated with the machine learning technique. The proposed approach is decomposed to solve users clustering and power allocation subproblems. The selection of optimal cluster heads (CHs) and their associated cluster members is based on Gale-Shapley matching game theoretical model with the application of Hungarian method. The CHs can harvest energy from the BS and transfer their surplus power to the primary user (PU) through wireless power transfer. In return, they are allowed to access the licensed band for secondary transmission. The power allocation to the users intended for power conservation at CHs is formulated as a probabilistic constraint, which is then solved by employing the support vector machine (SVM) algorithm. The simulation results demonstrate the efficacy of our proposed schemes that enable the CHs to transfer the residual power while ensuring maximum system throughput. The effects of different parameters on the performance are also studied.     

Boundary-Conforming Discontinuous Galerkin Methods via Extensions from Subdomains

A new way of devising numerical methods is introduced whose distinctive feature is the computation of a finite element approximation only in a polyhedral subdomain D{\mathsf{D}} of the original, possibly curved-boundary domain. The technique is applied to a discontinuous Galerkin method for the one-dimensional diffusion-reaction problem. Sharp a priori error estimates are obtained which identify conditions, on the subdomain D{\mathsf{D}} and the discretization parameters of the discontinuous Galerkin method, under which the method maintains its original optimal convergence properties. The error analysis is new even in the case in which D=W{\mathsf{D}}=\Omega . It allows to see that the uniform error at any given interval is bounded by an interpolation error associated to the interval plus a significantly smaller error of a global nature. Numerical results confirming the sharpness of the theoretical results are displayed. Also, preliminary numerical results illustrating the application of the method to two-dimensional second-order elliptic problems are shown.     

Sterile keratitis after corneal collagen crosslinking in a child

Corneal collagen crosslinking (CXL) is a non invasive technique used in halting the progression of keratoconus. Complications with this modality are rare. We report a case of an 8-year-old child who developed sterile infiltrates in the immediate postoperative period after uneventful corneal collagen crosslinking for keratoconus. The infiltrates resolved with topical steroid therapy. There was also present coexisting vernal keratoconjunctivitis (VKC) which was controlled with topical 2% cyclosporine A eye drops prior to crosslinking treatment. This case highlights importance of controlling VKC prior to CXL in keratoconus as it adds to the risk of developing post operative sterile keratitis.     

A Soluble Epoxide Hydrolase Inhibitor, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea,Ameliorates Experimental Autoimmune Encephalomyelitis

Polyunsaturated fatty acids (PUFAs) are essential FAs for human health. Cytochrome P450 oxygenates PUFAs to produce anti-inflammatory and pain-resolving epoxy fatty acids (EpFAs) and other oxylipins whose epoxide ring is opened by the soluble epoxide hydrolase (sEH/Ephx2), resulting in the formation of toxic and pro-inflammatory vicinal diols (dihydroxy-FAs). Pharmacological inhibition of sEH is a promising strategy for the treatment of pain, inflammation, cardiovascular diseases, and other conditions. We tested the efficacy of a potent, selective sEH inhibitor, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), in an animal model of multiple sclerosis (MS), experimental autoimmune encephalomyelitis (EAE). Prophylactic TPPU treatment significantly ameliorated EAE without affecting circulating white blood cell counts. TPPU accumulated in the spinal cords (SCs), which was correlated with plasma TPPU concentration. Targeted lipidomics in EAE SCs and plasma identified that TPPU blocked production of dihydroxy-FAs efficiently and increased some EpFA species including 12(13)-epoxy-octadecenoic acid (12(13)-EpOME) and 17(18)-epoxy-eicosatrienoic acid (17(18)-EpETE). TPPU did not alter levels of cyclooxygenase (COX-1/2) metabolites, while it increased 12-hydroxyeicosatetraenoic acid (12-HETE) and other 12/15-lipoxygenase metabolites. These analytical results are consistent with sEH inhibitors that reduce neuroinflammation and accelerate anti-inflammatory responses, providing the possibility that sEH inhibitors could be used as a disease modifying therapy, as well as for MS-associated pain relief.     

Calcific mitral stenosis in the hemodialysis patient

The dialysis patient is prone to elevations in the calcium phosphorus product and hyperparathyroidism, which contributes to valvular and vascular calcification. We present the case of a young lady on chronic dialysis that developed mitral calcification complicated by severe mitral stenosis, caseous calcification and retinal embolization. She subsequently required mitral valve replacement.     

Development and performance analysis of a novel agitated vessel

The objective of the present study was to design, fabricate and evaluate the performance of a novel airi-nducing impeller system with a specially designed air-inducing tube-set. The novel air-inducing impeller system, when attached to a conventional baffled agitated vessel, could convert it into an air-inducing reactor. Water was used as the working fluid and the characteristics of the impeller system such as critical speed, power consumption and gas holdup were investigated by varying the gas free liquid level, orifice immersion depth, bottom clearance and impeller speed. Results showed that this novel air-inducing impeller system induced the air at speeds lower than the critical speeds reported by most of the investigators in the literature.     

Nanoparticles in Clinical Translation for Cancer Therapy

The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner. This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment. The obstacles in the journey of nanodrug from clinic to market are reviewed. Furthermore, the latest developments in using nanoparticles in cancer therapy are also highlighted.     

Differential scanning calorimetric and free volume study of reactive compatibilization by EPM‐g‐MA of poly(trimethylene terephthalate)/EPDM blends

Differential scanning calorimetry (DSC) and positron annihilation lifetime measurements have been carried out to study the effect of the compatibilizer maleic anhydride grafted ethylene propylene copolymer (EPM‐g‐MA) in poly trimethylene terephthalate and ethylene propylene diene monomer (PTT/EPDM) immiscible blends. The DSC results for the blends of 50/50 and 30/70 compositions show two clear glass transition temperatures, indicating that the blends are two‐phase systems. With the addition of compatibilizer, the separation between the two glass transitions decreased, suggesting an increased interaction between the blend components with compatibilizer. At 5 wt % of compatibilizer, the separation between the T_gs reduced in both 50/50 and 30/70 blends. The positron results for the blends without compatibilizer showed an increase in relative fractional free volume, as the EPDM content in the blend is increased. This suggests the coalescence of free volume of EPDM with the free volumes of PTT due to phase separation. However, the effect of compatibilizer in the blends was clearly seen with the observed minimum in free volume parameters at 5% of the compatibilizer, further suggesting that this percent of compatibilizer seems to be the optimum value for these blends. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 740–747, 2006