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1.
Forschung im Ingenieurwesen - Das Arbeitsmittel in Wärmepumpen unterliegt einer Vielzahl von Anforderungen, welche für einen effizienten und sicheren Betrieb eingehalten werden...  相似文献   
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In this article, we present two efficient weighted fair queueing (WFQ) scheduling algorithms leaned on the well-known token bucket and leaky bucket shaping/policing algorithms. The performance of the presented algorithms is compared to those of the state-of-the-art WFQ approximations such as weighted round robin (WRR) and the recently proposed bin sort fair queueing (BSFQ). Our simulation results show that the proposed algorithms provide a better fairness at a lower implementation complexity while simultaneously achieving a comparable network utilization.  相似文献   
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Safety, local and systemic immunomodulation, and tumor response to treatment with aerosolized natural interleukin 2 (nIL-2) applied five times a day were studied in a Phase I trial in 16 patients with pulmonary malignancies refractory to conventional therapy. The toxicity of inhaled nIL-2 was different from that observed after systemic administration. Reversible airway irritation causing a nonproductive cough represented the dose-limiting toxicity. Mild to moderate reduction of the vital capacity and forced expiratory volume (FEV1) with minor effects on relative FEV1, peak expiratory flow, airway resistance, and PaO2 was experienced by individual patients. In 14 patients suffering from pulmonary metastases due to renal cell cancer, one durable complete response, one partial response, and one mixed response were observed. Inhalation of nIL-2 aerosol resulted in a dose-dependent expansion of pulmonary immunocompetent cells in bronchoalveolar lavage fluid. Posttreatment bronchoalveolar lavage showed an activated lymphocyte phenotype with increased HLA-DR expression. The only systemic biological effect detectable in peripheral blood was a marked increase of soluble interleukin 2 receptor serum levels. We conclude that treatment with aerosolized nIL-2 is an effective means for site-specific immunomodulation and deserves further investigation for the treatment of malignant and inflammatory lung disease.  相似文献   
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This paper describes the development and simulation of an unsteady state biofilter model used to predict dynamic behaviour of cyclically‐operated biofilters and compares it with experimental results obtained from three, parallel, bench‐scale biofilters treating both periodically fluctuating concentrations and constant concentrations of an α‐pinene‐laden gas stream. The dynamic model, using kinetic parameters estimated from the constant concentration biofilter, was able to predict the performance of cyclic biofilters operating at short cycle periods (ie, in the order of minutes and hours). Steady state kinetic data from a constant concentration biofilter can be used to predict unsteady state biofilter operation. At a 24 h cycle period, the dynamic model compared well with experimental results. For long cycle periods (ie, hours and days), removal efficiency decreased after periods of non‐loading: the longer the period of non‐loading, the poorer the biofilter's performance at the re‐commencement of pollutant loading. At longer time scales the model did not effectively predict transient behaviour, as adsorption and changes in kinetic parameters were not accounted for. Modelling results showed that similar biofiltration performance for the cyclic and constant concentration biofiltration of α‐pinene is expected for biofilters operating solely in the first order kinetics regime. Poorer performance for cyclic biofilters following Monod kinetics spanning the entire kinetics range is expected as the cycle amplitude increases. The most important parameters affecting the performance of a cyclically‐operated biofilter with short cycle periods are: amplitude of cyclic fluctuations, Cg, max/Cg, relative value of the half‐saturation constant in the Monod expression, Ks, and effective diffusivity of α‐pinene in the biofilm, De. Copyright © 2005 Society of Chemical Industry  相似文献   
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In the verified architecture microprocessor (VAMP) project we have designed, functionally verified, and synthesized a processor with full DLX instruction set, delayed branch, Tomasulo scheduler, maskable nested precise interrupts, pipelined fully IEEE compatible dual precision floating point unit with variable latency, and separate instruction and data caches. The verification has been carried out in the theorem proving system PVS. The processor has been implemented on a Xilinx FPGA. A shorter version of this article with the title “Instantiating uninterpreted functional units and memory system: functional verification of the VAMP” appeared in [8]. The work reported here was done while all the authors were with Saarland University.  相似文献   
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In this text we present``profile-based linguistic uniformity', a methoddesigned to compare language varieties on thebasis of a wide range of potentiallyheterogeneous linguistic variables. In manyrespects a parallel can be drawn with currentmethods in dialectometry (for an overview, see,Nerbonne and Heeringa, 2001; Heeringa, Nerbonneand Kleiweg, 2002): in both casesdissimilarities between varieties on the basisof individual variables are summarized inglobal dissimilarities, and a series oflanguage varieties are subsequently clusteredor charted using multivariate techniques suchas cluster analysis or multidimensionalscaling. This global similarity between themethods makes it possible to compare them andto investigate the implications of notabledifferences. In this text we specifically focuson, and defend one characteristic of ourmethodology, its profile-based nature.  相似文献   
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