A methodological approach to fully automated highly accelerated life tests

Microsystem Technologies - Highly accelerated life test (HALT) is a test methodology to evaluate reliability of mechanical and electromechanical devices. HALT is often used on devices that must be...     

Autonomic Nervous System in Obesity and Insulin-Resistance—The Complex Interplay between Leptin and Central Nervous System

The role of the autonomic nervous system in obesity and insulin-resistant conditions has been largely explored. However, the exact mechanisms involved in this relation have not been completely elucidated yet, since most of these mechanisms display a bi-directional effect. Insulin-resistance, for instance, can be caused by sympathetic activation, but, in turn, the associated hyperinsulinemia can activate the sympathetic branch of the autonomic nervous system. The picture is made even more complex by the implicated neural, hormonal and nutritional mechanisms. Among them, leptin plays a pivotal role, being involved not only in appetite regulation and glucose homeostasis but also in energy expenditure. The purpose of this review is to offer a comprehensive view of the complex interplay between leptin and the central nervous system, providing further insights on the impact of autonomic nervous system balance on adipose tissue and insulin-resistance. Furthermore, the link between the circadian clock and leptin and its effect on metabolism and energy balance will be evaluated.     

Design and test of a real-time shelf out-of-stock detector system

Microsystem Technologies - The shelf out-of-stock (SOOS) problem is relevant for retailers and producers since the absence of products on the shelf can lead to a significant reduction of...     

Determinants of Gd-enhanced MRI response to IFN-beta-1a treatment in relapsing-remitting multiple sclerosis

BACKGROUND: With the prevalence of antibiotic use, the diagnosis and management of Clostridium difficile disease requires assessment. METHODS: In a retrospective review, patients with a positive culture, toxin, or both during 1 year were identified. Recent literature was reviewed. Results of culture and toxin, prior antibiotic use, antibiotic treatment history and cost were analyzed. RESULTS: Of 592 patients tested, 101 were positive; 96 of 101 were available for review. Of those positive tested for both, 45% were positive for toxin and culture. Sixty-two of 96 were treated with antibiotics; metronidazole was used in 90%. Ten of 62 antibiotic treatments were changed (mean 3 days). Ten days of metronidazole is 1/200th the cost of vancomycin. CONCLUSIONS: In 55% of the positive cases in which culture and toxin were obtained, one test was negative. As metronidazole's efficacy and cost compares favorably with vancomycin, metronidazole is the drug of choice. Any changes made to antibiotic regimens occurred prior to the 6 days recommended in the literature.     

A Vision-Based Guidance System for UAV Navigation and Safe Landing using Natural Landmarks

In this paper a vision-based approach for guidance and safe landing of an Unmanned Aerial Vehicle (UAV) is proposed. The UAV is required to navigate from an initial to a final position in a partially known environment. The guidance system allows a remote user to define target areas from a high resolution aerial or satellite image to determine either the waypoints of the navigation trajectory or the landing area. A feature-based image-matching algorithm finds the natural landmarks and gives feedbacks to an onboard, hierarchical, behaviour-based control system for autonomous navigation and landing. Two algorithms for safe landing area detection are also proposed, based on a feature optical flow analysis. The main novelty is in the vision-based architecture, extensively tested on a helicopter, which, in particular, does not require any artificial landmark (e.g., helipad). Results show the appropriateness of the vision-based approach, which is robust to occlusions and light variations.     

A Visual Global Positioning System for Unmanned Aerial Vehicles Used in Photogrammetric Applications

The combination of photogrammetric aerial and terrestrial recording methods can provide new opportunities for photogrammetric applications. A UAV (Unmanned Aerial Vehicle), in our case a helicopter system, can cover both the aerial and quasi-terrestrial image acquisition methods. A UAV can be equipped with an on-board high resolution camera and a priori knowledge of the operating area where to perform photogrammetric tasks. In this general scenario our paper proposes vision-based techniques for localizing a UAV. Only natural landmarks provided by a feature tracking algorithm will be considered, without the help of visual beacons or landmarks with known positions. The novel idea is to perform global localization, position tracking and localization failure recovery (kidnapping) based only on visual matching between current view and available georeferenced satellite images. The matching is based on SIFT features and the system estimates the position of the UAV and its altitude on the base of the reference image. The vision system replaces the GPS signal combining position information from visual odometry and georeferenced imagery. Georeferenced satellite or aerial images must be available on-board beforehand or downloaded during the flight. The growing availability of high resolution satellite images (e.g., provided by Google Earth or other local information sources) makes this topic very interesting and timely. Experiments with both synthetic (i.e., taken from satellites or datasets and pre elaborated) and real world images have been performed to test the accuracy and the robustness of our method. Results show sufficient performance if compared with common GPS systems and give a good performance also in the altitude estimation, even if in this last case there are only preliminary results.     

Modelling and Forecasting Customer Navigation in Intelligent Retail Environments

Understanding shopper behaviour is one of the keys to success for retailers. In particular, it is necessary that managers know which retail attributes are important to which shoppers and their main goal is to improve the consumer shopping experience. In this work, we present sCREEN (Consumer REtail ExperieNce), an intelligent mechatronic system for indoor navigation assistance in retail environments that minimizes the need for active tagging and does not require metrics maps. The tracking system is based on Ultra-wideband technology. The digital devices are installed in the shopping carts and baskets and sCREEN allows modelling and forecasting customer navigation in retail environments. This paper contributes the design of an intelligent mechatronic system with the use of a novel Hidden Markov Models (HMMs) for the representation of shoppers’ shelf/category attraction and usual retail scenarios such as product out of stock or changes on store layout. Observations are viewed as a perceived intelligent system performance. By forecasting consumers next shelf/category attraction, the system can present the item location information to the consumer, including a walking route map to a location of the product in the retail store, and/or the number of an aisle in which the product is located. Effective and efficient design processes for mechatronic systems are a prerequisite for competitiveness in an intelligent retail environment. Experiments are performed in a real retail environment that is a German supermarket, during business hours. A dataset, with consumers trajectories, timestamps and the corresponding ground truth for training as well as evaluating the HMM, have been built and made publicly available. The results in terms of Precision, Recall and F1-score demonstrate the effectiveness and suitability of our approach, with a precision value that exceeds the 76% in all test cases.     

An offline parallel architecture for forensic multimedia classification

Multimedia Tools and Applications - Nowadays, the volume of the multimedia heterogeneous evidence presented for digital forensic analysis has significantly increased, thus requiring the application...     

A Framework for Simulation and Testing of UAVs in Cooperative Scenarios

Today, Unmanned Aerial Vehicles (UAVs) have deeply modified the concepts of surveillance, Search&Rescue, aerial photogrammetry, mapping, etc. The kinds of missions grow continuously; missions are in most cases performed by a fleet of cooperating autonomous and heterogeneous vehicles. These systems are really complex and it becomes fundamental to simulate any mission stage to exploit benefits of simulations like repeatability, modularity and low cost. In this paper a framework for simulation and testing of UAVs in cooperative scenarios is presented. The framework, based on modularity and stratification in different specialized layers, allows an easy switching from simulated to real environments, thus reducing testing and debugging times, especially in a training context. Results obtained using the proposed framework on some test cases are also reported.