CO2 process intensification of algae oil extraction to biodiesel

Algae-to-biodiesel processes are hindered by high costs and low energy return on investment.^1,2. Herein, three foci in research improve algae-to-biodiesel processes by: (1) reducing high installation and energy costs in the CO₂ sequestration, cultivation, and harvesting stages; (2) improving oil extraction and biodiesel generation; and (3) increasing utilization of the proteins in lipid-extracted biomass (e.g., for animal feed), as well as the omega-3 fatty acids for nutraceuticals and food supplements. A process is introduced that uses carbon dioxide to aid in all three of these foci. CO₂ is used first in the form of microbubbles to lyse algae cell walls, releasing triglyceride oils. CO₂ also aids with transesterification of these triglycerides using methanol. At low temperatures (353.15–368.15 K) and intermediate pressures (5–10 MMPa), carbon dioxide causes methanol to dissolve partially in the triglyceride phase and triglyceride to dissolve partially in the methanol phase, increasing the transesterification reaction rate. Due to the nondestructive nature of these processes, other metabolites can also be harvested providing improvements in both mass and economic efficiency with an overall sharp reduction in the modeled price of biodiesel.     

An enhanced security mechanism through blockchain for E-polling/counting process using IoT devices

Wireless Networks - One of the biggest challenges in political mayhem is visible during the election process where no stone is kept unturned in order to gain the power. Further, due to poll...     

Reactive power pricing structure for hydroelectric power station in condenser mode operation

Reactive power support is critical for system security and pricing of reactive power is a vital issue in restructured environment. Peaking units at hydroelectric power plant in condenser mode operation can provide major reactive power support. Therefore costing structure for hydroelectric power plant incorporating various cost components in condenser mode operation is presented in this paper. Major cost components include capital cost component, changeover cost component and a cost component related to number of service hours in condenser mode operation. A methodology is proposed based on these components. A case study of Koyna Hydro Electric Power Plant (KHEPP) is elaborated.     

A trust computed framework for IoT devices and fog computing environment

Wireless Networks - In this paper, we have demoralized the transmission processing concerns of fog nodes and IoT device layer attack during the handoff (mobility) of IoT devices in the fog...     

Design and development of enhanced bandwidth multi‐frequency slotted antenna for 4G‐LTE/WiMAX/WLAN and S/C/X‐band applications

A multi‐frequency rectangular slot antenna for 4G‐LTE/WiMAX/WLAN and S/C/X‐bands applications is presented. The proposed antenna is comprised of rectangular slot, a pair of E‐shaped stubs, and an inverted T‐shaped stub and excited using staircase feed line. These employed structures help to achieve multiband resonance at four different frequency bands. The proposed multiband slot antenna is simulated, fabricated and tested experimentally. The experimental results show that the antenna resonates at 2.24, 4.2, 5.25, and 9.3 GHz with impedance bandwidth of 640 MHz (2.17‐2.82 GHz) covering WiMAX (802.16e), Space to Earth communications, 4G‐LTE, IEEE 802.11b/g WLAN systems defined for S‐band applications. Also the proposed antenna exhibits bandwidth of 280 MHz (4.1‐4.38 GHz) for Aeronautical and Radio navigation applications, 80 MHz (4.2‐4.28 GHz) for uncoordinated indoor systems,1060 MHz (5.04‐6.1 GHz) for the IEEE 802.11a WLAN system defined for C‐band applications and 2380 MHz (7.9‐10.28 GHz) defined for X‐band applications. Further, the radiation patterns for the designed antenna are measured in anechoic chamber and are found to agree well with simulated results.     

Secure multimedia data processing scheme in medical applications

People communicate in a variety of ways via multimedia through the propagation of various techniques. Nowadays, variety of multimedia frameworks or techniques is used in various applications such as industries, software processing, vehicles and medical systems. The usage of multimedia frameworks in healthcare systems makes it possible to process, record and store huge amount of information generated by various medical records. However, the processing and management of huge records of every individual lead to overload the security risk and human efforts. The aim of this paper is to propose a secure and efficient technique that helps the medical organizations to process every record of individuals in a secure and efficient way. The proposed mechanism is validated against various security and processing metrics over conventional mechanisms such as Response Time, Message Alteration Record, Trusted Classification Accuracy and Record Accuracy. The analyzed results claim the significant improvement of proposed mechanism as compare to other schemes.

     

Antidiabetic Potential of Commonly Consumed Legumes: A Review

Over the last few decades, lifestyle changes have resulted in a drastic increase in the incidence of diabetes all over the world, especially in the developing countries. Oral hypoglycemic agents and insulin form the mainstay in controlling diabetes, but they have prominent side effects and fail to significantly alter the course of diabetic complications. Appropriate diet and exercise programs that form a part of lifestyle modifications have proven to be greatly effective in the management of this disease. Dietary therapy is showing a bright future in the prevention and treatment of diabetes. Legumes, owing to their high nutritive value, are increasingly being used in dietetic formulations in the treatment and prevention of diabetes on account of their antidiabetic potential. Given this background, this paper reviews the glucose- and lipid-lowering action possessed by various commonly consumed legumes through several animal and human studies. It is concluded that the various legumes not only have varying degrees of antidiabetic potential but are also beneficial in decreasing the risk factors for cardiovascular and renal disease.     

Intracellular delivery of etoposide loaded biodegradable nanoparticles: cytotoxicity and cellular uptake studies

The preferred delivery systems for anticancer drugs would be the one which would have selective and effective destruction of cancer cells. In the present study etoposide (ETO) loaded nanoparticles (NP) were prepared using PLGA (ETO-PLGA NP), PLGA-MPEG block copolymer (ETO-PLGA-MPEG NP) and PLGA-Pluronic copolymer (ETO-PLGA-PLU NP) and they were evaluated for cytotoxicity and cellular uptake studies using two cancer cell lines, L1210 and DU145. The IC50 values for L1210 cells were 18.0, 6.2, 4.8 and 5.4 microM and for DU145 cells the IC50 values were 98.4, 75.1, 60.1 and 71.3 microM for ETO, ETO-PLGA NP, ETO-PLGA-MPEG NP and ETO-PLGA-PLU NP respectively. The increased cytotoxicities were attributed to increased uptake of the NPs by the cells. Moreover the ETO loaded PLGA-MPEG NP and PLGA-Pluronic NP showed a sustained cytotoxic effect till 5 days on both the cell lines. Results of the long term cytotoxicity study concluded that the drug loaded PLGA nanoparticulate formulations were efficient in decreasing the viability of the L1210 cells over a period of three days, whereas the pure drug exerted its maximum efficiency on the day one itself. Z-stack confocal images of NPs showed fluorescence activity in each section of DU 145 and L1210 cells indicating that the nanoparticles were internalized by the cells. The study concluded that ETO loaded PLGA NPs had higher cytotoxicity compared with that of the free drug and ETO-PLGA-MPEG NP and ETO-PLGA-PLU NP had higher cell uptake efficiency compared with that of ETO-PLGA NP. The developed PLGA based NPs shows promise to be used for cancer therapy.     

Chemokine-Cytokine Networks in the Head and Neck Tumor Microenvironment

Head and neck squamous cell carcinomas (HNSCCs) are aggressive diseases with a dismal patient prognosis. Despite significant advances in treatment modalities, the five-year survival rate in patients with HNSCC has improved marginally and therefore warrants a comprehensive understanding of the HNSCC biology. Alterations in the cellular and non-cellular components of the HNSCC tumor micro-environment (TME) play a critical role in regulating many hallmarks of cancer development including evasion of apoptosis, activation of invasion, metastasis, angiogenesis, response to therapy, immune escape mechanisms, deregulation of energetics, and therefore the development of an overall aggressive HNSCC phenotype. Cytokines and chemokines are small secretory proteins produced by neoplastic or stromal cells, controlling complex and dynamic cell–cell interactions in the TME to regulate many cancer hallmarks. This review summarizes the current understanding of the complex cytokine/chemokine networks in the HNSCC TME, their role in activating diverse signaling pathways and promoting tumor progression, metastasis, and therapeutic resistance development.     

Food processing a tool to pesticide residue dissipation – A review

Food safety is an area of growing worldwide concern on account of its direct bearing on human health. The presence of harmful pesticide residues in food has caused a great concern among the consumers. Hence, world over to tackle food safety issues, organic farming is being propagated. However, due to several reasons, diffusion and acceptance of this approach in developing countries has been very slow. Therefore, it is important in the transient phase that some pragmatic solution should be developed to tackle this situation of food safety. Food processing treatments such as washing, peeling, canning or cooking lead to a significant reduction of pesticide residues. In this background this paper reviews the common food processing operations along with the degree of residue removal in each process. The processes reviewed include: baking, bread making, dairy product manufacture, drying, thermal processing, fermentation, freezing, infusion, juicing, malting, milling, parboiling, peeling, peeling and cooking, storage, storage and milling, washing, washing and cooking, washing and drying, washing and peeling, washing peeling and juicing and wine making. Extensive literature review demonstrates that in most cases processing leads to large reductions in residue levels in the prepared food, particularly through washing, peeling and cooking operations.