Introduction.

This article introduces the current issue of Health Psychology. The call for early intervention to prevent adulthood health problems and the need to consider each period of children's lives within its developmental perspective are the main emphases in this special issue of the journal. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

TES modeling for analysis of a video multiplexer

The transport of video images is likely to be a major application of high-speed networks of the future. These applications are capable of utilizing the high bandwidths that will become available with the advent of B-ISDN. In this paper, we propose a new methodology (called TES) for modeling the frame bitrate stream generated by compressed video sources. The main characteristic of this method is that it can model an arbitrary marginal distribution and approximate the autocorrelation structure of the random bitrate process generated by compressed frames. We present a modeling example utilizing this method, based on data from a video coding algorithm employing a layering technique. Using the source model, we develop a simulation model of a multiplexer of video sources. We show that this model can be used to address a number of design issues that arise in this class of problem. In particular, we show that for a layered video coding algorithm, it is possible to have a gain in the number of sources multiplexed at the cost of some loss of low priority packets.     

IgGs-Abzymes from the Sera of Patients with Multiple Sclerosis Recognize and Hydrolyze miRNAs

Autoantibodies-abzymes hydrolyzing DNA, myelin basic protein, and oligosaccharides have been revealed in the sera of patients with multiple sclerosis (MS). In MS, specific microRNAs are found in blood and cerebrospinal fluid, which are characterized by increased expression. Autoantibodies, specifically hydrolyzing four different miRNAs, were first detected in the blood of schizophrenia patients. Here, we present the first evidence that 23 IgG antibodies of MS patients effectively recognize and hydrolyze four neuroregulatory miRNAs (miR-137, miR-9-5p, miR-219-2-3p, and miR-219-5p) and four immunoregulatory miRNAs (miR-21-3p, miR-146a-3p, miR-155-5p, and miR-326). Several known criteria were checked to show that the recognition and hydrolysis of miRNAs is an intrinsic property of MS IgGs. The hydrolysis of all miRNAs is mostly site-specific. The major and moderate sites of the hydrolysis of each miRNA for most of the IgG preparations coincided; however, some of them showed other specific sites of splitting. Several individual IgGs hydrolyzed some miRNAs almost nonspecifically at nearly all internucleoside bonds or demonstrated a combination of site-specific and nonspecific splitting. Maximum average relative activity (RA) was observed in the hydrolysis of miR-155-5p for IgGs of patients of two types of MS—clinically isolated syndrome and relapsing-remitting MS—but was also high for patients with primary progressive and secondary progressive MS. Differences between RAs of IgGs of four groups of MS patients and healthy donors were statistically significant (p < 0.015). There was a tendency of decreasing efficiency of hydrolysis of all eight miRNAs during remission compared with the exacerbation of the disease.     

Simulating the effect of a high density electric current pulse on the stress field during plastic deformation

A certain pulse of electric current combined with plastic deformation is a powerful tool for improving the formability of hard-to-deform metal alloys. In recent years, much research has indicated that the current not only improves macro-mechanical properties but also influences microstructural-level phenomena such as recrystallization, local phase transformation, grain refinement, and even amorphous nanocrystallization. Despite the huge experimental dataset, virtually no focus has been placed on phenomenon??s computing. In this fashion, present paper concerned with the continuum-level numerical analysis of the pulse impact on the stress field during plastic deformation. Computation conducted herein has shown that a high density electric current pulsing weakens the stress field during plastic deformation. Ultimate results of the study should be useful in developing the novel metal processing technology.     

Workload, control, and social support effects on serum lipids: A longitudinal study among apparently healthy employed adults.

The authors investigated the direct and interactive effects of the job demand– control–support (JDC-S) model’s components on subsequent changes in high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides (TRI) separately for male and female employees. In contrast to all 14 past studies on these relationships, the authors used a longitudinal design. Study participants (N = 1,137, 66% men) were all apparently healthy employees who underwent a routine health check at 2 points in time (Time 1 and Time 2) about 22 months apart. In these analyses, the authors controlled for the Time 1 level of each criterion and for other confounders. Most of the direct and moderating effects found did not support the predictions of the JDC-S model; this finding is in agreement with the majority of past cross-sectional studies. The authors did not find any evidence supporting the existence of a reverse causation for either of the components of the JDC-S model. The authors suggest that serum lipids may not be a physiological mechanism mediating the effects of the JDC-S model on atherosclerotic diseases. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The influence of transition metals – Fe,Co, Cu on transformation of organic matters from Domanic rocks in hydrothermal catalytic system

Character of conversion of organic matter from Domanic rocks of Pervomaiskoye field (Tatarstan) of Semiluki horizon of upper Devonian deposits in the hydrothermal-catalytic system at temperature of 300?°C in carbon dioxide medium was studied with the application of complex of oil-soluble precursors of catalysts containing Fe, Co, and Cu. In presence of catalysts complex, content of organic extract increases, in which content of hydrocarbon fractions, saturated and aromatic hydrocarbons, increases 1.5 times, while resins content decreases by two times. As result of kerogen destruction in products of experiments, the content of asphaltenes and carbonaceous substances such as carbenes and carboides increase.     

The Forgotten “Old-Darwinian” Synthesis: The Evolutionary Theory of Ludwig H. Plate (1862–1937)

The German zoologist and geneticist Ludwig Plate was a pupil and successor of the “German Darwin” Ernst Haeckel as the director of the Institute of Zoology at Jena University. Plate campaigned for a revival of the original Darwinism. His research program, which he labelled “old-Darwinism”, proclaimed the synthesis of selectionism with “moderate Lamarckism” and orthogenesis.This article reconstructs and analyses Plate’s “old-Darwinian” synthesis and sheds light on Plate’s controversial biography, especially his conflict with Haeckel. Our research was supported by the Deutsche Forschungsgemeinschaft (HO 2143/5–2).