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The functional reanimation of paralyzed limbs has been a longstanding goal of neural prosthetic research, but clinically successful applications have been elusive. Natural voluntary limb movement requires four major elements: actuators (i.e., motor units), sensors (i.e., somatosensory afferents), commands (i.e., cerebral cortical activity), and control (i.e., integration of the previous three elements at various levels of the neuraxis). Prosthetic equivalents of each of these elements are, as yet, primitive and often cumbersome to deploy, but new technologies promise substantial improvements for all. This article focuses on one such technology, bionic neuon (BION) modular microimplants, and its relationship to alternative and complementary technologies. The challenge remains to select and integrate them into systems that can be tailored efficiently to the widely disparate needs of patients with various patterns of weakness and paralysis. 相似文献
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Koenen Karestan C.; Stellman Jeanne Mager; Stellman Steven D.; Sommer John F. Jr. 《Canadian Metallurgical Quarterly》2003,71(6):980
Risk factors affecting the course of posttraumatic stress disorder (PTSD) are poorly understood. As part of a larger study on characterizing exposure to herbicides in Vietnam, the authors investigated this issue in a random sample of 1,377 American Legionnaires who had served in Southeast Asia during the Vietnam War and were followed over a 14-year period. High combat exposure, perceived negative community attitudes at homecoming, minority race, depression symptoms at Time 1, and more anger at Time 1 predicted a more chronic course. Community involvement at Time 1 was protective and associated with decreased risk at Time 2. Discomfort in disclosing Vietnam experiences was associated with an increased risk for developing PTSD but did not predict its course. Combat exposure predicted PTSD course more strongly than any other risk factor. Findings suggest recovery from PTSD is significantly influenced by perceived social support. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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This research focuses on the spatial economics of geothermal district energy (DE) systems that distribute hot fluids through a pipeline network to multiple thermal customers. We argue here that DE is held back by uncertainty about its economic feasibility when implemented in real places. DE works best with high urban densities, but in the US the best geothermal resources are in the less-populated west. Economic geography theory suggests that the optimal size of a DE firm's service area should depend on the trade-off between the economies of scale inherent in a large service area and the greater network development costs and heat loss involved in serving a large area. The HEATMAP© software program developed by Washington State University was used to study the feasibility of numerous scenarios for a proposed DE system in Mammoth Lakes, California. Results indicate that the core area of the town is large enough, dense enough, and in close enough proximity to the resource for profitable DE development. Proposed ski village developments would increase the thermal load density and significantly enhance its ability to remain competitive with other fuels, even in pessimistic sensitivity analyses regarding geothermal heat input costs, public participation, and retro-fitting costs. 相似文献
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Gerald Leach 《Energy Policy》1991,19(10):918-925
The UK differs from may other industrialized nations in that its carbon dioxide (CO2) emissions from energy use have declined in recent years despite relatively rapid economic growth. In all sectors but transport, substantial reductions have already occurred in the level of carbon emissions per unit of GDP output. At the same time, a number of official and unofficial studies have pointed out that the UK has one of the largest remaining potentials amongst comparable industrialized countries for achieving further CO2 reductions through the implementation of cost-effective energy efficiency and fuel switching measures. This paper discusses past and present patterns of energy use and carbons emissions in the UK. The analysis then examines historical trends in UK energy policy and presents policy options for further reducing the UK's energy-use and carbon emissions in the future. 相似文献
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Allen Daniel N.; Strauss Gregory P.; Kemtes Karen A.; Goldstein Gerald 《Canadian Metallurgical Quarterly》2007,21(6):713
Hemispheric involvement in reasoning abilities has been debated for some time, and it remains unclear whether the right hemisphere's involvement in problem solving is modality specific or dependent on the type of spatial reasoning required. In the current study, 2 types of nonverbal reasoning abilities were examined, spatial reasoning and proportional reasoning, in 109 patients with cerebrovascular disease that was confined to either the right or the left hemisphere or was diffuse in nature. Results indicated that no lateralizing effects were present based on type of spatial reasoning. Findings are consistent with the suggestion that higher order cognitive processes involved in nonverbal abstraction and problem solving are not strongly lateralized to the right hemisphere but rather are more generally distributed throughout the cortex. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献