Phosphorus‐containing polyaryloxydiphenylsilanes with high flame retardance arising from a phosphorus–silicon synergistic effect

Polyaryloxydiphenylsilanes were prepared from phosphorus‐containing diols and diphenydichlorolsilane through solution polymerization. With a stoichiometric imbalance in feed monomers, the resulting polymers exhibited moderate melting points and good processing properties. The polymers prepared showed initial decomposition temperatures above 340 °C, excellent thermal stability, high char yields at 850 °C and very high limited oxygen index values of 56–59. The polymers' char yields and their (P + Si) contents showed linear relationships. © 2003 Society of Chemical Industry     

双极关键工艺的在线统计分析

采用了双极晶体管作为双极工艺的测试结构,将在线工艺的统计分析理论应用于双极工艺,研制了双极工艺的统计分析软件。最后给出了双极工艺的某些分析结果。     

Intravaginal Controlled Administration of Flurogestone Acetate: (III) Development of Rate-Control Vaginal Devices

A Rate-Control vaginal device was developed which overcomes the low bioavailability and unpredictable Q - t^1/2 type release and absorption rate profiles of flurogestone acetate delivered by the currently marketed Syncro-Mate pessary.

The in vitro release and vaginal absorption profiles from the Rate-Control vaginal device were run simultaneously, a linear Q - t relationship was obtained with a significant improvement in bioavailability. A mathematical model was developed to correlate the in vitro drug release and the vaginal absorption profiles of flurogestone acetate from the vaginal devices.

The design, development and the simultaneous release and absorption profiles of flurogestone acetate from this new vaginal device were outlined and discussed.     

Development of Anticandidal Delivery Systems: (I) Anticandidal Activities of Antifungal Agents and Synergistic Combination with Other Drugs

Susceptibility testing with antifungal agents, e. g., minimum inhibitory concentration (MIC) determination, is performed to obtain reliable data that permit selection of the most suitable agents for treatment of an infective condition. To determine the drugs that provide maximum effectiveness against oral candidiasis, the MICs of various antifungal agents were determined. Also, synergism between two chosen antifungal agents was evaluated, and the effect of benzocaine, an anesthetic, and hydrocortisone, an antiinflammatory agent, on their MICs was examined. It was observed that among all the drugs tested, clotrimazole was the most promising candidate for use as an oral local antifungal. The combination of clotrimazole and chlorhexidine resulted in a decrease in the MIC. While the addition of hydrocortisone to this combination resulted in a slight increase in the MIC, the inclusion of benzocaine resulted in a substantial decrease in the MIC of the antifungal agent combination.     

Characterization of in Vitro Transdermal Iontophoretic Delivery of Insulin

In-vitro studies were conducted to characterize the transdermal iontophoretic delivery of insulin, thus avoiding potential complications from various biological variations, which may be encountered during in-vivo studies. The proteolytic degradation of insulin in skin homogenates and degradation under the experimental conditions used was investigated. Appropriate adjuvants were incorporated to minimize the potential degradation problems of insulin. ¹²⁵I-Insulin was observed to penetrate into and accumulate in the skin during the iontophoresis period. It was then released gradually from this depot, as a mixture of intact and ¹²⁵-I labelled fragments, into the receptor medium. Drug desorption studies supported the theory of skin depot or reservoir formation. It was found that an electric field could be used to facilitate the desorption of drug from the depot. The post-application flux of insulin (or its fragments) from the skin depot formed during iontophoresis was monitored to study the factors affecting the iontophoretic delivery of insulin. Stripping and delipidization of the skin were noted to increase the skin permeation rate of insulin. The cumulative radioactivity permeated and accumulated in the skin was higher at pH 3.6 than at pH 7.4. The iontophoresis-facilitated transdermal delivery was observed to increase with increasing duration of current application and increasing donor concentration of insulin. Modulation of drug delivery by multiple applications was also found to be feasible.     

Effects and properties of poly(arylene ether benzonitrile)s of various molecular weights blended with sulfonated poly(ether ether ketone)

Poly(arylene ether benzonitrile) (PAEBN) was synthesized with 2,6‐dichlorobenzonitrile and biphenol. PAEBNs with various molecular weights (MWs), 1,640,000 and 185,000 g/mol, were synthesized by control of the stoichiometry of the monomers and were blended with sulfonated poly(ether ether ketone) (SPEEK). The effects of MW on the water uptake, swelling, methanol permeability, and proton conductivity of the SPEEK/PAEBN blend membranes were investigated. The molecular mobility of the SPEEK/PAEBN blends was also examined in this study. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

改进工艺操作方法 降低脱硅锆能耗

从分析脱硅的条件出发,引导出新的工艺操作方法、工艺参数和加料方法。用一年的生产实践说明该新工艺操作方法的技术经济效益。     

压电双晶片传感器灵敏度特性分析

本文用模态分析法详细分析了压电双晶片力、振动、粗糙度传感器的位移特性及灵敏度特性,并给出了灵敏度与压电材料参数及晶片几何尺寸的关系。     

臭氧-生物活性炭深度处理亚热带地区原水中试试验

本研究针对南方亚热带地区常规给水处理工艺下的砂滤出水，应用臭氧一生物活性炭工艺进行深度处理中试试验，经过一个水文年（12个月）的运行，结果表明：在不同的后臭氧投加量（1．0～3．0mg／L）下，随着后臭氧投加量的增加，后臭氧接触塔及炭滤池对CODMn的去除率总体上呈逐步升高的趋势；后臭氧投加量和臭氧后水浊度、炭滤池对锰的去除率有明显的相关性；当后臭氧投加量为1．8～2．0mg／L时，各项水质指标取得较好的处理效果，已无需增大投药量；系统在冬季水温较低时运行对可以生物降解的CODMn与氨氮的去除率未出现下降趋势，表明本工艺在我国南方亚热带地区有广阔的应用前景。     

微电脑控制水质处理技术的设计与实践

在铁合金冶炼电炉(2×16．5 MVA)循环冷却水系统的设计中,将微电脑控制水质处理技术应用于电炉闭路循环冷却水的自动控制,使用NKC-3405缓蚀阻垢剂、NKC-615杀菌灭藻剂,对电炉循环冷却水存在腐蚀、沉积物及菌、藻类微生物的情况,将人工加药控制改为微电脑自动加药及控制,减少人为误差,实现加药自动化,取得了较好的效果;同时提高了设备装备水平,在技术上实现了质的飞跃。