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A review of isolates of Neisseria meningitidis and other laboratory evidence of meningococcal infection was carried out for the period 1990-1995. Thirty-three patients with evidence of meningococcal disease were identified over the six year period. Group B organisms were the most commonly identified, but an increase in Group C has occurred and is almost equal in number. Data from clinical, laboratory and public health sources should be centralized in a National Surveillance Centre.  相似文献   
3.
Information Systems Frontiers - The way open data resources of varied type and volume are used by software applications remains only partly known. In this study, following CRoss-Industry Standard...  相似文献   
4.
The aim of this paper is the path loss modelling for the radiolocation services in radio communication networks, particularly in cellular networks. The main results of the measurements obtained in the physical layer of the UMTS are introduced. A new method for the utilization of the multipath propagation phenomenon to improve the estimation of the distance between the MS (mobile station) and the BS (base station) is outlined. This method significantly increases the quality of location services in systems which use a radio interface with DS (direct sequence) CDMA (code division multiple access).  相似文献   
5.
Natural languages have been taken as models of systems with strong statistical correlations. In such systems the usual probabilistic limiting laws (Gauss etc.) are no more valid and the concept of higher order temperatures can be applied. It has been shown that this is the case in such languages as English, German, French, Russian and Japanese, for letter and word statistics. The corresponding temperatures (up to the 5-th order), entropies and statistical moments have been calculated and their mutual relations have been checked.... erst wenn du plötzlich Fänger wirst des Balles, den eine ewige Mitspielerin dir zuwarf, ... erst dann ist Fangen-können ein Vermögen, nicht deines, einer Welt.(... only when you suddenly catch the ball which the eternal fellow player throws to you,... only then the catching ability is an accomplishment, not of you, but of the world.)R. M. Rilke (from the motto of [3])Supported by Committee of Scientific Research, Warsaw (KBN), Project Nr. 20412 91 01.  相似文献   
6.
A miniaturized ceramic differential scanning calorimeter (MC-DSC) with integrated oven and crucible is presented. Despite its small size of only 11 mm × 39 mm × 1.5 mm, all functions of a conventional DSC apparatus are integrated in this novel device - including the oven. The MC-DSC is fully manufactured in thick-film and green glass ceramic tape-based low temperature co-fired ceramics (LTCC) technology. Therefore, production costs are considered to be low. Initial results using indium as a sample material show a good dynamic performance of the MC-DSC. Full width at half maximum of the melting peak is 2.4 °C (sample mass approx. 11 mg, heating rate approx. 50 °C/min). Repeatability of the indium melting point is within ±0.02 °C. The melting peak area increases linearly with the sample mass up to at least 26 mg. Simulations of a strongly simplified finite element model of the MC-DSC are in a good agreement with measurement results allowing a model-based prediction of its basic characteristics.  相似文献   
7.
This work presents the influence of annealing on the structure and stoichiometry of europium (Eu)-doped titanium dioxide (TiO2). Thin films were fabricated by magnetron sputtering from a metallic Ti-Eu target in oxygen atmosphere and deposited on silicon and SiO2 substrates. After deposition the selected samples were additionally annealed in air up to 1070 K.Film properties were examined by means of X-ray diffraction (XRD), atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS) and the results were analyzed together with the undoped TiO2 thin films prepared under similar technological conditions.XRD results showed that depending on the Eu content, as-deposited thin films consisted of the TiO2-anatase or TiO2-rutile.An additional annealing will result in the growth of anatase crystals up to 35 nm, but anatase to rutile phase transformation has not been recorded. AFM images display high quality and a dense nanocrystalline structure. From the XPS Ti2p spectra the 4+oxidation state of Ti was confirmed. The O1s XPS spectra displayed the presence of an O2− photoelectron peak accompanied by an additional broader peak that originates from hydroxyl species chemisorbed at the sample surface. It has been found that Eu dopant increases the OH content on the surface of prepared TiO2:Eu thin films. The calculated O/Ti ratio was in the range of 1.85-2.04 depending on the sample.  相似文献   
8.
This paper describes a new multi-heterojunction n +pp photovoltaic infrared photodetector. The device has been developed specifically for operation at temperatures of 200–300K in the long wavelength (8–14 μm) range of the infrared spectrum. The new structure solves the perennial problems of poor quantum efficiency and low dynamic resistance found in conventional long wavelength infrared photovoltaic detectors when operated near room temperature. Computer simulations show that devices with properly optimized multiple heterojunctions are capable of achieving the performance limits imposed by the statistical nature of thermal generation-recombination processes. In order to demonstrate the technology, multiple heterojunction devices have been fabricated on epilayers grown by isothermal vapor phase epitaxy of HgCdTe and in situ As p-type doping. The detector structures were formed using a combination of conventional dry etching, angled ion milling, and angled thermal evaporation for contact metal deposition. These multi-junction n +pp HgCdTe heterostructure devices exhibit performances which make them useful for many applications. D* of optically immersed multiple heterostructure photovoltaic detectors exceeding 108cmHz1/2/W were measured at λ=10.6 μm and T=300K.  相似文献   
9.
Mathematical modeling of signaling pathways and regulatory networks has been supporting experimental research for some time now. Sensitivity analysis, aimed at finding model parameters whose changes yield significantly altered cellular responses, is an important part of modeling work. However, sensitivity methods are often directly transplanted from analysis of technical systems, and thus, they may not serve the purposes of analysis of biological systems. This paper presents a novel sensitivity analysis method that is particularly suited to the task of searching for potential molecular drug targets in signaling pathways. Using two sample models of pathways, p53/Mdm2 regulatory module and IFN-β-induced JAK/STAT signaling pathway, we show that the method leads to biologically relevant conclusions, identifying processes suitable for targeted pharmacological inhibition, represented by the reduction of kinetic parameter values. That, in turn, facilitates subsequent search for active drug components.  相似文献   
10.
Investigation was focused on the impact of high power ultrasound (HPUS), also called thermosonication, on the oxygen permeation properties (permeability, solubility and diffusion coefficients) of barrier films aimed for food packaging. For this purpose, biaxially oriented polypropylene (BOPP) coated with acrylic/polyvinylidene chloride (BOPPAcPVDC) and biaxially oriented coextruded polypropylene (BOPPcoex) were used. The physical–chemical profile of the samples was determined using goniometry. There is a significant impact only of extreme HPUS conditions (the longest time and the highest amplitude) on the permeability, solubility and diffusion coefficients of oxygen through the BOPP films. The highest influence on the oxygen permeability in both investigated BOPP samples involved an HPUS with an amplitude of 100% during a 6 min treatment. However, BOPP samples showed different sensitivities at lower HPUS treatments. © 2017 Society of Chemical Industry  相似文献   
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