全文获取类型
收费全文 | 154篇 |
免费 | 2篇 |
国内免费 | 1篇 |
专业分类
化学工业 | 28篇 |
机械仪表 | 4篇 |
建筑科学 | 21篇 |
能源动力 | 5篇 |
轻工业 | 16篇 |
无线电 | 5篇 |
一般工业技术 | 15篇 |
冶金工业 | 13篇 |
原子能技术 | 4篇 |
自动化技术 | 46篇 |
出版年
2023年 | 1篇 |
2021年 | 3篇 |
2020年 | 1篇 |
2019年 | 2篇 |
2018年 | 3篇 |
2017年 | 2篇 |
2016年 | 7篇 |
2015年 | 4篇 |
2014年 | 5篇 |
2013年 | 11篇 |
2012年 | 8篇 |
2011年 | 6篇 |
2010年 | 8篇 |
2009年 | 7篇 |
2008年 | 9篇 |
2007年 | 7篇 |
2006年 | 7篇 |
2005年 | 3篇 |
2004年 | 7篇 |
2003年 | 5篇 |
2002年 | 6篇 |
2001年 | 4篇 |
2000年 | 3篇 |
1999年 | 3篇 |
1998年 | 3篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1995年 | 4篇 |
1994年 | 4篇 |
1993年 | 2篇 |
1991年 | 1篇 |
1989年 | 2篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1974年 | 1篇 |
排序方式: 共有157条查询结果,搜索用时 15 毫秒
1.
2.
J. Iivari 《欧洲信息系统杂志》1995,4(3):143-158
CASE (Computer Aided Software/Systems Engineering) tools are claimed to increase the productivity of systems development and the quality of developed systems. Existing empirical research on CASE effectiveness is entirely based on subjective, perceptual data. In order to interpret the existing evidence, it is useful to understand factors affecting these perceptions. This paper studies the impact of demographic variables such as education and experience, CASE adoption process variables such as training and participation, and CASE product variables such as perceived trialability, perceived complexity, perceived demonstrability and perceived compatibility on CASE effectiveness perceptions such as relative advantage, quality and productivity of systems development and work unit effects. Results based on a survey of 105 individual CASE users show that these effectiveness criteria are highly intercorrelated and that CASE experience, participation in CASE selection and implementation, perceived quality and quantity of training, and especially perceived complexity affect CASE effectiveness perceptions. 相似文献
3.
Tiina Reponen Anne Hyv rinen Juhani Ruuskanen Taisto Raunemaa Aino Nevalainen 《Journal of aerosol science》1994,25(8):1595-1603
Concentrations and types of airborne fungal spores and their aerodynamic sizes were studied in nine buildings with mould problems and in matched reference buildings in order to characterize the exposure in buildings with mould problems. Samples were taken with Andersen six-stage impactors in the autumn and winter. In winter, total concentrations of fungal spores in buildings with mould problems were twice those in reference buildings, even though all concentrations were quite small. In the autumn, the differences were less obvious due to the masking effect of outdoor air fungi. Also, the compositions of fungal genera differed in buildings with mould problems from that in reference buildings. The difference was most significant in the size range 2.1-4.7 μm. The size distribution of fungal spores in dwellings with mould problems skewed towards larger particles than in reference dwellings. The observed differences in size distribution indicate differences in airborne behaviour of fungal spores and, consequently, in respiratory exposure. 相似文献
4.
Vesa Halava Tero Harju Juhani Karhumki Michel Latteux 《Theoretical computer science》2007,380(3):355-362
In the Post Correspondence Problem (PCP) an instance (h,g) consists of two morphisms h and g, and the problem is to determine whether or not there exists a nonempty word w such that h(w)=g(w). Here we prove that the PCP is decidable for instances with unique blocks using the decidability of the marked PCP. Also, we show that it is decidable whether an instance satisfying the uniqueness condition for continuations has an infinite solution. These results establish a new and larger class of decidable instances of the PCP, including the class of marked instances. 相似文献
5.
6.
Antti Juhani Kaijalainen Pasi Suikkanen L. Pentti Karjalainen John J. Jonas 《Metallurgical and Materials Transactions A》2014,45(3):1273-1283
The effect of austenite pancaking in the non-recrystallization regime on microstructure and texture evolution and thereby on bendability was investigated in an ultrahigh-strength strip steel with a martensitic-bainitic microstructure. The results indicate that an increase in rolling reduction (R tot) below the non-recrystallization temperature, which improves the strength and toughness properties, increases the intensities of the ~{554}〈225〉 α and ~{112}〈110〉 α texture components along the strip centerline and of the ~{112}〈111〉 α component at the surface region. Even with the highest R tot of 79 pct, the bendability along the rolling direction was good, but the preferred alignment of rod-shaped MA constituents along the rolling direction led to a dramatic decrease in the bendability transverse to the rolling direction, with severe cracking occurring even at small bending angles. The early cracking is attributed to localization of the strain in narrow shear bands. It is concluded that the Rtot value has to be limited to guarantee successful bendability. 相似文献
7.
8.
The present study analyzes the mechanisms and facilitators behind joint learning in R&D collaborations by way of a qualitative comparative case study analyzing three supplier relationships and three internal R&D partnerships of the focal organization. The results suggest a single joint learning process for internal and external relationships in which the role of the customer and the facilitation of the joint learning process vary depending on the context. Whereas the role of motivation is central for joint learning in the internal relationships, mutual trust is important to the external relationships. 相似文献
9.
Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody–Drug Conjugation Chemistry
下载免费PDF全文
![点击此处可从《ChemMedChem》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Dr. Filip S. Ekholm Henna Pynnönen Anja Vilkman Virve Pitkänen Dr. Jari Helin Juhani Saarinen Tero Satomaa 《ChemMedChem》2016,11(22):2501-2505
Antibody–drug conjugates (ADCs) are promising alternatives to naked antibodies for selective drug‐delivery applications and treatment of diseases such as cancer. Construction of ADCs relies upon site‐selective, efficient and mild conjugation technologies. The choice of a chemical linker is especially important, as it affects the overall properties of the ADC. We envisioned that hydrophilic bifunctional chemical linkers based on carbohydrates would be a useful class of derivatization agents for the construction of linker–drug conjugates and ADCs. Herein we describe the synthesis of carbohydrate‐based derivatization agents, glycolinker–drug conjugates featuring the tubulin inhibitor monomethyl auristatin E and an ADC based on an anti‐EGFR antibody. In addition, an initial in vitro cytotoxicity evaluation of the individual components and the ADC is provided against EGFR‐positive cancer cells. 相似文献
10.
Quantitative structure-activity relationships (QSARs) have proved increasingly useful for predicting the biological activities of molecules (e.g., their binding affinities to different receptors) and can be used in environmental chemistry as a preliminary tool for screening the activities of untested molecules, producing valuable information on which compounds should be tested more thoroughly with experimental affinity assays or in animals. The predictive ability of the consensus kNN QSAR method is corroborated here using a diverse set of 245 compounds, which have been assayed for their relative binding affinities to the estrogen receptor of four species: human (ER alpha and ER beta), calf, mouse, and rat. Leave-one-out cross-validation (LOO-CV) and gamma-randomization tests were applied to the QSAR models for internal validation, and separate training and test sets were used for external validation. The internal predictive abilities of the consensus models for all five data sets were convincing, with cross-validated correlation coefficients (LOO-CV q2 values) varying from 0.69 (human ER beta data) to 0.79 (human ER alpha data). The external predictive abilities were also encouraging, as the predictive r2 scores (pr-r2 values) varied from 0.62 (human ER beta data) to 0.77 (calf and mouse data). The results indicate that consensus kNN QSAR is a feasible method for rapid screening of the estrogenic activity of organic compounds. 相似文献