A knowledge construction methodology to automate case-based learning using clinical documents

The case-based learning (CBL) approach has gained attention in medical education as an alternative to traditional learning methodology. However, current CBL systems do not facilitate and provide computer-based domain knowledge to medical students for solving real-world clinical cases during CBL practice. To automate CBL, clinical documents are beneficial for constructing domain knowledge. In the literature, most systems and methodologies require a knowledge engineer to construct machine-readable knowledge. Keeping in view these facts, we present a knowledge construction methodology (KCM-CD) to construct domain knowledge ontology (i.e., structured declarative knowledge) from unstructured text in a systematic way using artificial intelligence techniques, with minimum intervention from a knowledge engineer. To utilize the strength of humans and computers, and to realize the KCM-CD methodology, an interactive case-based learning system(iCBLS) was developed. Finally, the developed ontological model was evaluated to evaluate the quality of domain knowledge in terms of coherence measure. The results showed that the overall domain model has positive coherence values, indicating that all words in each branch of the domain ontology are correlated with each other and the quality of the developed model is acceptable.     

Performance of a new pipe material UHMWPE against disinfectant decay in water distribution networks

Clean Technologies and Environmental Policy - The concentration of any disinfectant is a major parameter which is used to evaluate the quality of water. Chlorine is the most common disinfecting...     

Synthesis and characterization of conducting copolymers from aniline and o‐anisidine in HCl solutions

Conducting poly(aniline‐co‐o‐anisidine) (PAS) films with different ratios of aniline units in the polymer chain were prepared by oxidative polymerization of different molar ratios of aniline and o‐anisidine in 1 M HCl using cyclic voltammetry. Due to the much higher reactivity of o‐anisidine, the structure and properties of PASs were found to be dominated by the o‐anisidine units. The polymerization of poly‐o‐anisidine and PASs followed zero‐order kinetics with respect to formation of the polymer (film thickness) and the autocatalytic polymerization of aniline was completely inhibited. In contrast to polyaniline, a decrease in the polymerization temperature was found to increase the amount of copolymer formed and its redox charge. The presence of aniline units in PASs led to a pronounced increase in the molecular weight and conductivity, and a decrease in the solubility in organic solvents. Repetitive charging/discharging cycles showed that PASs resist degradation more than polyaniline. Copyright © 2003 Society of Chemical Industry     

Electrical and magnetic properties of lithium borate glass containing iron

Journal of Materials Science Letters -     

Effect of the addition of Fe2O3 and heat treatment duration on the magnetic susceptibility of V2O5-P2O5-B2O3 glass system

The effect of the addition of Fe₂O₃ and heat treatment duration on the magnetic susceptibility of vanadium borophosphate glass were studied. The magnetic susceptibility of glass samples was found to increase with increasing Fe₂O₃ content, which may be explained by the formation of the FeO₆ group and the change of Fe²⁺ to Fe³⁺ which has higher paramagnetic properties. No detectable changes in the magnetic susceptibility with heat treatment for the samples containing 0.0, 0.5 and 1.0 mol% Fe₂O₃ was observed. The magnetic susceptibility for the heat treated samples containing 2.5, 5.0 and 7.5 mol% Fe₂O₃ decreases sharply with increasing duration of heat treatment up to 6 h and then remains almost constant. The sharp decrease in magnetic susceptibility of 2.5 mol% Fe₂O₃ is attributed to the increase in the number of ferrous ions. The sharp decrease for samples containing 5.0 and 7.5 mol% Fe₂O₃ is attributed to the increase in the number of Fe³⁺ in tetrahedral co-ordination. The rate of crystallization owing to the heat treatment was calculated and was found to increase with increasing iron oxide content. The geometry of crystallization was found to be in three-, two-and one-dimension(s) for samples containing 2.5, 5.0 and 7.5 mol% Fe₂O₃, respectively.     

Corrosion Control by water‐soluble extracts from leaves of economic plants

Water extracts from leaves of date palm, phoenix dactylifera, henna, Lawsonia inermis, and corn, Zea mays, were tested as corrosion inhibitors for steel, aluminum, copper and brass in acid chloride and sodium hydroxide solutions using weight loss, solution analysis and potential measurements. The inhibition action was found to critically depend on metal type and solution composition. Only, date palm and henna extracts were found highly effective in reducing corrosion rate of steel in acid chloride solutions and aluminum in sodium hydroxide solutions. The inhibition efficiency increased with increasing the concentration of the extract. The inhibition was interpreted in terms of chemisorption of some active ingredients in the leaves according to Temkin isotherm.     

Tumor size and prognosis in aggressively treated osteosarcoma

PURPOSE: The aim of this retrospective analysis was to investigate the prognostic significance and optimal measures of tumor size in osteosarcoma treated with intensive neoadjuvant chemotherapy. PATIENTS AND METHODS: Initial anterior-posterior (AP) and lateral x-ray films of 128 patients treated within the trials Cooperative Osteosarcoma Study (COSS)-80, -82, and -86, were evaluated for the following three tumor diameters: length, width, and depth. Metastasis-free survival (MFS) analyses were performed in univariate and multivariate models with one, two, and three dimensions of the tumor as absolute or relative measures (tumor length, referred to bone length, plane and volume to body-surface area). RESULTS: Univariate analyses of MFS showed a high prognostic significance of all absolute measures. Relative measures, at best, showed a comparable predictive value. Cox regression analysis indicated the high prognostic significance of absolute tumor volume (ATV; P < .0001) and histologic response (P < .0001). None of 19 patients with an ATV < or = 70 cm3 and only four of 53 with an ATV < or = 150 cm3 relapsed, while in patients with an ATV more than 150 cm3, the relapse rate remained 40% to 60%, irrespective of further increase in volume. CONCLUSION: Initial tumor size is an important and easily obtainable prognostic factor in osteosarcoma and may serve as a basis for risk-adapted therapy. It is best represented by the absolute three-dimensional measure ATV. There is a cut-off point regarding the incidence of metastases at a tumor volume of approximately 150 cm3 as calculated from two-plane x-ray films.     

Delay-dependent anti-windup synthesis for stability of constrained state delay systems using pole-constraints

This paper proposes the design of anti-windup compensator gain for stability of actuator input constrained state delay systems using constrained pole-position of the closed-loop. Based on Delay-Dependent Lyapunov-Krasovskii functionals and local sector conditions, a new LMI characterization is derived that ensures closed-loop asymptotic stability of constrained state delay systems while accounting upper bound fixed state delay and largest lower bound of the system’s pole-position in the formulation of anti-windup gain. Besides, at saturation, the method significantly nullifies the inherent slow dynamics present in the system. It is shown in the comparative numerical examples that the LMI formulation draws stability with improved time-domain performance.     

Observer-based leader-following consensus of one-sided Lipschitz multi-agent systems over input saturation and directed graphs

This paper investigates a local observer-based leader-following consensus control of one-sided Lipschitz (OSL) multi-agent systems (MASs) under input saturation. The proposed consensus control scheme has been formulated by using the OSL property, input saturation, directed graphs, estimated states, and quadratic inner-boundedness condition by attaining the regional stability. It is assumed that the graph always includes a (directed) spanning tree with respect to the leader root to develop matrix inequalities for investigating parameters of the proposed observer and consensus protocols. Further, a new observer-based consensus tracking method for MASs with saturation, concerning independent topologies for communicating outputs and estimates over the network, is explored to deal with a more perplexing and realistic situation. In contrast to the traditional methods, the proposed consensus approach considers output feedback and deals with the input saturation for a generalized class of nonlinear systems. The efficiency of the obtained results is illustrated via application to a group of five moving agents in the Cartesian coordinates.