Requirements engineering in health care: the example of chemotherapy planning in paediatric oncology

Health care is characterized by highly complex processes of patient care that require unusual amount of communication between different health care professionals of different institutions. Sub-optimal processes can significantly impact on the patient’s health, increase the consumption of services and resources and in severe cases can lead to the patient death. For these reasons, requirements engineering for the development of information technology in health care is a complex process as well: without constant and rigorous evaluation, the impact of new systems on the quality of care is unknown and it is possible that badly designed systems significantly harm patients. To overcome these limitations, we present and discuss an approach to requirements engineering that we applied for the development of applications for chemotherapy planning in paediatric oncology. Chemotherapy planning in paediatric oncology is complex and time-consuming and errors must be avoided by all means. In the multi-hospital/multi-trial-centre environment of paediatric oncology, it is especially difficult and time-consuming to analyse requirements. Our approach combines a grounded theory approach with evolutionary prototyping based on the constant development and refinement of a generic domain model, in this case a domain model for chemotherapy planning in paediatric oncology. The prototypes were introduced in medical centres and final results show that the developed generic domain model is adequate.     

Specification methods for material-handling control algorithms in flexible manufacturing systems

Good methods are needed to specify, test, and debug material-handling control logic. This article surveys a number of representative methods for defining and describing control algorithms for programmable material-handling equipment used in flexible manufacturing systems. The methods are evaluated with regard to their suitability for communication between people and as bases for interfaces to automatic program generators. It is concluded that no single method is entirely satisfactory. Three methods (position diagrams, function block diagrams, and operation networks) have potential to be combined into an effective hybrid approach that minimizes the need for the user to switch between various conceptual models.     

A process oriented semantics of the PRAM-language FORK

The parallel language FORK [1], based on a scalable shared memory model, is a PASCAL-like language with some additional parallel constructs. A PRAM (Parallel Random Access Machine) algorithm can be expressed on a high level of abstraction as a FORK program which is translated into efficient PRAM code guaranteeing theoretically predicted runtimes.

In this paper, we concentrate on those features of the language FORK related to parallelism, such as the group concept, a shared memory access and synchronous or asynchronous execution. We present a trace-based denotational interleaving semantics where processes describe synchronous computations. Processes are created or deleted dynamically and run asynchronously. Interleaving rules reflect the underlying CRCW (concurrent-read-concurrent-write) PRAM model.     

Biocide polymers

Summary Potential polymeric herbicides have been synthesized by reacting poly(acrylic acid)s with 3-aniino-1,2,4-triazole and 1-acetyl-5-amino-1,2,4-triazole, respectively. The produced copolymers contained the active moieties as pendant groups in the range of 3 to 27 per cent of weight and with a content of carboxyl groups up to 95 mol-%. The hydrolytic release of 3-amino-1,2,4-triazole was investigated.Part 12: M. Hartmann, H,-J. Bauer, A. Pritzsche and K. Wermann, Makromol. Chem., in press     

Computer-aided design in mechanisms

The man-machine dialog is very important for the design process. In this paper a program system, based on the minicomputer KRS 4201 (ROBOTRON), is demonstrated by using an interactive graphical screen. This program system provides the opportunity to analyze and synthesize mechanisms up to 16 links. The application is demonstrated by designing a front-loader-system for a truck. Real-time animation of seven-bar linkages and coupler curves, including velocity and acceleration, are shown.