The Heritage of the Productive Landscape: Landscape Design for Rural Areas in the Netherlands, 1954-1985

In the current debate about the future of the Dutch countryside, more and more attention is drawn to the role of landscape heritage. Spatial designers are asked to translate historic identities into spatial forms in order to bridge the gap between past and future. Special cultural heritage policies are developed to stimulate a shift in design practice and to increase awareness of the value of cultural landscapes. Because interpretation of the rural landscape is often rooted in nostalgia, most conservation efforts are directed at old historical landscapes and rural scenes. But what about modern rural landscapes? How do these landscapes relate to the emerging issue of heritage protection and development? To answer this question the historical significance of these landscapes was examined by analyzing their design in the slipstream of post-war reconstruction. Attention was also given to their possible future in a planning and management context that is increasingly influenced by a public and professional demand for landscape conservation and heritage. We argue that these landscapes are at odds with the values and core convictions of the current heritage policies and merit recognition in their own right.     

Exploring the potential of recovering 1‐butanol from aqueous solutions by liquid demixing upon addition of carbohydrates or salts

BACKGROUND: Fermentative production of 1‐butanol yields dilute aqueous solutions. Recovery of the butanol from these solutions is most commonly performed by energy‐intensive distillation. This work investigated the liquid‐liquid (L‐L) phase behavior of mixtures of butanol and water to explore the potential of using L‐L phase separation as a recovery possibility for 1‐butanol. The phase behavior is preferably influenced by compounds already present in the fermentation, such as carbohydrates and salts. RESULTS: The L‐L phase equilibria of butanol and water were determined in the presence of glucose, fructose, sucrose, NaCl, LiCl and CaCl₂. The aqueous and organic phase split is more pronounced in the presence of salts than in the presence of carbohydrates. Demixing is achieved with about 0.3 kg salt kg^?1 aqueous phase containing 40 g of butanol. CONCLUSION: Operation of L‐L based recovery using salts or carbohydrates requires extreme concentrations of those compounds. For feed material containing 40 g kg^?1 butanol, the tested carbohydrates do not influence the phase equilibria sufficiently to allow butanol separation. Fermentative butanol concentrations up to 70 g kg^?1 are required to create an effective L‐L phase split. The remaining residual aqueous carbohydrate solution might be used as feed for a following fermentation. Copyright © 2011 Society of Chemical Industry     

An industrial view on compact modeling

Compact modeling is an area that gets more and more mature. Collaborations and standardization efforts have emerged. In this paper we present some special requirements that are important when constructing physics-based compact models. We will substantiate our statements on two recent examples, an inductor model and a MOSFET model.     

Flow-Based Network Management: A Report from the IRTF NMRG Workshop

This is the report on the Workshop on Flow-Based Network Management, held within the 37th IRTF NMRG meeting, during IETF 93, on 24th July 2015, in Prague, Czech Republic. Following the tradition of the IRTF NMRG, the workshop focused on technologies, developments, and challenges of using flow-level traffic measurements for network management.     

Conditions and costs for renewables electricity grid connection: Examples in Europe

This paper compares conditions and costs for RES-E grid connection in selected European countries. These are Germany, the Netherlands, the United Kingdom, Sweden, Austria, Lithuania and Slovenia. Country specific case studies are presented for wind onshore and offshore, biomass and photovoltaic power systems, as based on literature reviews and stakeholder interviews. It is shown that, especially for wind offshore, the allocation of grid connection costs can form a significant barrier for the installation of new RES-E generation if the developer has to bear all such costs. If energy policy makers want to reduce the barriers for new large-scale RES-E deployment, then it is concluded that the grid connection costs should be covered by the respective grid operator. These costs may then be recouped by increasing consumer tariffs for the use of the grid.     

ENDOW (efficient development of offshore wind farms): modelling wake and boundary layer interactions

While experience gained through the offshore wind energy projects currently operating is valuable, a major uncertainty in estimating power production lies in the prediction of the dynamic links between the atmosphere and wind turbines in offshore regimes. The objective of the ENDOW project was to evaluate, enhance and interface wake and boundary layer models for utilization offshore. The project resulted in a significant advance in the state of the art in both wake and marine boundary layer models, leading to improved prediction of wind speed and turbulence profiles within large offshore wind farms. Use of new databases from existing offshore wind farms and detailed wake profiles collected using sodar provided a unique opportunity to undertake the first comprehensive evaluation of wake models in the offshore environment. The results of wake model performance in different wind speed, stability and roughness conditions relative to observations provided criteria for their improvement. Mesoscale model simulations were used to evaluate the impact of thermal flows, roughness and topography on offshore wind speeds. The model hierarchy developed under ENDOW forms the basis of design tools for use by wind energy developers and turbine manufacturers to optimize power output from offshore wind farms through minimized wake effects and optimal grid connections. The design tools are being built onto existing regional‐scale models and wind farm design software which was developed with EU funding and is in use currently by wind energy developers. Copyright © 2004 John Wiley & Sons, Ltd.     

A Rule-Based Microcomputer System for Electroencephalogram Evaluation

This paper describes a method for implementation of a rulebased system on a sinple 8-bit microcomputer. The approach has been successfully implemented and tested by analyzing EEG's recorded from renal patients.     

A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease

The recruitment of T cells is a crucial component in the inflammatory cascade of the body. The process involves the transport of T cells through the vascular system and their stable arrest to vessel walls at the site of inflammation, followed by extravasation and subsequent infiltration into tissue. Here, we describe an assay to study 3D T cell dynamics under flow in real time using a high-throughput, artificial membrane-free microfluidic platform that allows unimpeded extravasation of T cells. We show that primary human T cells adhere to endothelial vessel walls upon perfusion of microvessels and can be stimulated to undergo transendothelial migration (TEM) by TNFα-mediated vascular inflammation and the presence of CXCL12 gradients or ECM-embedded melanoma cells. Notably, migratory behavior was found to differ depending on T cell activation states. The assay is unique in its comprehensiveness for modelling T cell trafficking, arrest, extravasation and migration, all in one system, combined with its throughput, quality of imaging and ease of use. We envision routine use of this assay to study immunological processes and expect it to spur research in the fields of immunological disorders, immuno-oncology and the development of novel immunotherapeutics.