Influence of Different Additives on the Interaction of Quinolone Antibiotic Drug with Surfactant: Conductivity and Cloud Point Measurement Study

Conductometric and cloud point (CP) measurement studies have been performed to investigate the interaction of tetradecyltrimethylammonium bromide (TTAB) and Triton® X-100 (TX-100) with ciprofloxacin hydrochloride (CFH) in different solvents over the temperature range of 295.15–315.15 K. CFH is used for the treatment of various bacterial infections. The observed critical micelle concentration (CMC) values of TTAB were found to be reduced in the presence of electrolytes (Na₂SO₄/Na₃PO₄), and this reduction proceeds with the elevation of salt concentration. The order of the CMC of TTAB follows the trend: > >. The observed CMC values of TTAB were found to increase with increasing temperature and decrease with increasing concentration of CFH in aqueous medium. The values of Gibbs free energy of micellization () for the TTAB/TTAB + CFH mixture were found to be negative, implying spontaneous micellization. The estimated CP of TX-100 decreases with increasing concentration of TX-100 in aqueous medium. The CP values first decrease with increasing concentration of CFH and then increase at higher concentration of CFH almost in all cases investigated. The values of free energy of clouding were found to be positive in all cases studied implying that phase separation of TX-100 was nonspontaneous. The other thermodynamic parameters associated with the micellization of TTAB and the phase separation of TX-100 were estimated and explained.     

Engineering carbon quantum dots for photomediated theranostics

Carbon quantum dots (CQDs) have emerged as potential alternatives to classical metal-based semiconductor quantum dots (QDs) due to the abundance of their precursors, their ease of synthesis, high biocompatibility, low cost, and particularly their strong photoresponsiveness, tunability, and stability. Light is a versatile, tunable stimulus that can provide spatiotemporal control. Its interaction with CQDs elicits interesting responses such as wavelength-dependent optical emissions, charge/electron transfer, and heat generation, processes that are suitable for a range of photomediated bioapplications. The carbogenic core and surface characteristics of CQDs can be tuned through versatile engineering strategies to endow specific optical and physicochemical properties, while conjugation with specific moieties can enable the design of targeted probes. Fundamental approaches to tune the responses of CQDs to photo-interactions and the design of bionanoprobes are presented, which enable biomedical applications involving diagnostics and therapeutics. These strategies represent comprehensive platforms for engineering multifunctional probes for nanomedicine, and the design of QD probes with a range of metal-free and emerging 2D materials.

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Investigation of OSN properties of PDMS membrane for the retention of dilute solutes with potential industrial applications

Few commercially available membranes can be used for organic solvent nanofiltration (OSN). Applying OSN in chemical industries is nevertheless of high interest to cut with energy consumption linked to solvent recycling and soluble catalysts recovery. A commercial membrane, PERVAP4060, was used to investigate the retention of dilute solutes in toluene feeds and to mimic metathesis medium. The studied solutes were R-BINAP a neutral polyaromatic molecule used in metathesis chemistry, tetraoctylammonium bromide (ToABr), a charged molecule used as a homogeneous catalyst and n-hexadecane. Retention of polar ToABr (95%) was higher than that of neutral R-BINAP (80%). The transfer mechanism, either pore flow or solution-diffusion, was discussed. All the results obtained suggested that the transport is governed by the solution-diffusion mechanism. The measured retentions could be explained in terms of solubility affinities and diffusion coefficients. The stability and performances of PERVAP4060 were well established, showing the strong potential for industrial applications. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137, 48359.     

Control of Listeria monocytogenes on turkey frankfurters by generally-recognized-as-safe preservatives

Generally-recognized-as-safe chemicals applied to the surfaces of turkey frankfurters were evaluated for their ability to reduce populations of or inhibit the growth of Listeria monocytogenes. Frankfurters were treated prior to inoculation by dipping for 1 min in a solution of one of four preservatives (sodium benzoate, sodium propionate, potassium sorbate, and sodium diacetate) at three different concentrations (15, 20, and 25% [wt/vol]), with < 0.3% of the preservative being present for each frankfurter. Subsequently, 0.1 ml of a five-strain mixture of L. monocytogenes (10(6) CFU/ml) was used to surface inoculate each frankfurter separately in a sterile stomacher bag. Inoculated frankfurter bags were held at 4, 13, and 22 degrees C, and L. monocytogenes cells were enumerated at 0, 3, 7, 10, and 14 days of storage. The results of this study revealed that at all three concentrations of all four preservatives, the initial populations of L. monocytogenes decreased immediately by 1 to 2 log10 CFU/g. After 14 days of storage at 4 degrees C, L. monocytogenes counts for all treated frankfurters were 3 to 4 log10 CFU/g less than those for the untreated frankfurters. After 14 days of storage at 13 degrees C, L. monocytogenes counts for frankfurters treated with 25% sodium benzoate or 25% sodium diacetate were 3.5 to 4.5 log10 CFU/g less than those for untreated frankfurters, and those for frankfurters treated with 25% sodium propionate or 25% potassium sorbate were 2.5 log10 CFU/g less than those for untreated frankfurters. In all instances, the degree of growth inhibition was directly proportional to the concentration of the preservative. Only frankfurters treated with 25% sodium diacetate or sodium benzoate were significantly inhibitory to L. monocytogenes when held at 22 degrees C for 7 days or longer. Interestingly, the untreated frankfurters held at 22 degrees C were spoiled within 7 days, with copious slime formation, whereas there was no evidence of slime on any treated frankfurters after 14 days of storage.     

Mass-rearing of the redlegged ham beetle, Necrobia rufipes De Geer (Coleoptera: Cleridae) for laboratory research

A new protocol for mass-rearing the redlegged ham beetle, Necrobia rufipes De Geer, in the laboratory is described, that facilitates the production of large numbers of insects with minimal handling. A culture medium comprised of finely ground (150 μm) dried fish, dry dog food and pieces of dried cured ham was tested on N. rufipes. This rearing medium produced significantly larger population numbers when compared with a range of published and unpublished methods. When reared on this medium with initial colonies of 200 mixed sex adult beetles, there was more than a three-fold increase in N. rufipes adult populations from the original numbers over a 7-8 week period. This simple procedure minimizes cannibalism as the larvae were shifted into glass vials for pupal cell formation.     

Bioreduction of Hexavalent Chromium in Flow-Through Quartz Sand Columns

Hexavalent chromium (Cr(VI)) contamination of soil and groundwater is a major environmental concern for some industrial sites and most of the U.S. Department of Energy sites. Cr(VI) is toxic and fairly mobile in groundwater. Bioreduction of Cr(VI) to less toxic and less mobile Cr(III) is considered to be a feasible option. Among the Cr(VI) reducing bacteria, Shewanella oneidensis MR-1 (MR-1) has been shown to be effective in metal reduction under anaerobic conditions. Data on bioreduction of Cr(VI) by MR-1 in a flow-through soil column that better approximates the subsurface condition are not available. The objective of this research project was to study the bioreduction of Cr(VI) by MR-1 in a continuous-flow quartz sand column system. MR-1 was found to be very effective in reducing Cr(VI) to Cr(III) for concentrations ranging from 0.055 mM (2.85?mg/L) to 0.006 mM (0.31?mg/L). The amount of Cr(VI) reduced prior to its breakthrough was found to be inversely proportional to its concentration in the feed due to increased inhibition of microbial activity and a residual reduction of 20–45% of Cr(VI) was observed even after its breakthrough.     

Identifying correlates of breaks in occupational sitting: a cross-sectional study

Office workers are commonly targeted in interventions to modify their sitting behaviour, yet there is limited evidence of the correlates of breaks in sitting to inform intervention development. This study identifies the individual, workplace and spatial configuration correlates of the frequency of breaks in sitting (number/hour) in office workers (n?=?5531) stratified by office type (private-enclosed, shared, open plan). All behaviours and potential correlates were measured via self-report using an online cross-sectional survey. Regression analyses revealed age was the only socio-demographic characteristic associated with frequency of breaks in sitting in all office types. Greater job autonomy and local connectivity were positively associated with frequency of breaks in sitting in shared and open-plan offices. In open-plan offices co-worker proximity was negatively associated with frequency of breaks in sitting. Co-worker visibility was positively associated with frequency of breaks in sitting in all office types. This study demonstrates that individual, workplace and spatial configuration factors are all associated with the frequency of breaks in sitting and that these relationships differ by office type. These observations extend prior studies that have only examined correlates at a single level (e.g. the individual). This evidence could be useful to guide future interventions in the design of workplaces to increase breaks in sitting and workers’ physical activity.     

A load-aware energy-efficient and throughput-maximized asynchronous duty cycle MAC for wireless sensor networks

Being a pivotal resource, conservation of energy has been considered as the most striking issue in the wireless sensor network research. Several works have been performed in the last years to devise duty cycle based MAC protocols which optimize energy conservation emphasizing low traffic load scenario. In contrast, considering the high traffic situation, another research trend has been continuing to optimize both energy efficiency and channel utilization employing rate and congestion control at the MAC layer. In this paper, we propose A Load-aware Energy-efficient and Throughput-maximized Asynchronous Duty Cycle MAC (LET-MAC) protocol for wireless sensor networks to provide an integrated solution at the MAC layer considering both the low-and high-traffic scenario. Through extensive simulation using ns-2, we have evaluated the performance of LET-MAC. LET-MAC achieves significant energy conservation during low traffic load (i.e., no event), compared to the prior asynchronous protocol, RI-MAC, as well as attains optimal throughput through maximizing the channel utilization and maintains lower delay in regard to the CSMA/CA-like protocol during a high volume of traffic (i.e., when an event occurs).     

Unmanned Aerial Vehicle-Aided 5G NR for Enhanced Network in Urban Scenarios

International Journal of Wireless Information Networks - Recently, Unmanned Aerial Vehicles (UAVs) are being utilized to ensure a better solution to a dependable and cost-effective wireless...