Increasing the heat capacity of heat exchangers is a crucial need for modern devices. The thermal conductivity of the usual fluids and the Nusselt (Nu) number of flows containing such fluids are two bottlenecks in the way of increasing heat delivery in the heat exchangers. For this reason, nanofluids have been introduced. The effect of utilizing a Cu-water nanofluid as a coolant of two hot pipes in a square cavity is investigated numerically with a two-component lattice Boltzmann method. The volume fraction of nanoparticles is assumed to be constant (0.03) while the Richardson (Ri) number varies from 0.02 to 20. Results show that the effectiveness of nanoparticles is better observed in the natural convection mode. However, sedimentation is also very probable at high Ri numbers, which significantly reduces the effectiveness of the nanoparticles. Configurations which produce a natural convection stream similar to the forced convection one as well as the configurations with high spacing and hence, low heat stream interactions, are the best choices for a uniform heat rate from the pipes. 相似文献
Abnormal activation of Toll-like receptor (TLRs) signaling can result in colon cancer development. The aim of this study was to investigate the expression of important TLRs in different histological types of colorectal polyps and evaluate their relationship with intestinal microbiota. The expression levels of TLR2, 3, 4, and 5 were analyzed in intestinal biopsy specimens of 21 hyperplastic polyp (HP), 16 sessile serrated adenoma (SSA), 29 tubular adenoma (TA), 21 villous/tubulovillous (VP/TVP) cases, and 31 normal controls. In addition, selected gut bacteria including Streptococcus bovis, Enterococcus faecalis, Enterotoxigenic Bacteroides fragilis (ETBF), Fusobacterium nucleatum, Porphyromonas spp., Lactobacillus spp., Roseburia spp., and Bifidobacterium spp. were quantified in fecal samples using absolute qRT PCR, and, finally, the association between TLRs and these gut microbiota- was evaluated by Spearman’s correlation coefficient. Higher expression of TLR2 and TLR4 in VP/TVP and TA, and lower expression levels of TLR3 and TLR5 in all type of polyps were observed. The differences in TLR expression patterns was not only dependent on the histology, location, size, and dysplasia grade of polyps but also related to the intestinal microbiota patterns. TLR2 and TLR4 expression was directly associated with the F. nucleatum, E. faecalis, S. bovis, Porphyromonas, and inversely to Bifidobacterium, Lactobacillus, and Roseburia quantity. Furthermore, TLR3 and TLR5 expression was directly associated with Bifidobacterium, Roseburia, and Lactobacillus quantity. Our results suggest a possible critical role of TLRs during colorectal polyp progression. An abnormal regulation of TLRs in relation to gut microbial quantity may contribute to carcinogenesis. 相似文献
The Journal of Supercomputing - With the expansion in the use of IoT, increasing the efficiency of these networks has become even more significant. Objects need reliable communications at suitable... 相似文献
Weekly storage of coolness in heavy walls (walls with large thermal inertia or large characteristic time constants or low Fourier numbers) was investigated numerically by considering one-dimensional heat conduction through the walls. The study consisted of first analyzing the heat flow through a single wall and considering various boundary conditions on the inside. The boundary conditions were: constant inside air tempeture throughout the day, variable inside air temperature on a 24-hour cycle, and variable inside air temperature on a 48-hour cycle. Next, the heat flow through walls was studied through a thermal network analysis of a simple building. In this case it was assumed that the ambient air temperature (following a periodic distribution) was increased suddenly and followed this new distribution for many days thereafter.It was concluded that walls with high thermal inertia or time constant can store coolness for several days. The larger the time constant of the wall (for example adobe as compared with brick) the longer it takes for the wall temperature to reach a steady periodic distribution after the change has occurred. However, because of low thermal conductivity of adobe, the retrieval of the stored coolness in these walls is slow, and the mean daily temperature of the room air in the adobe building does not change appreciably beyond seven days after the change. Increase of the wall thickness beyond 50 cm does not improve the thermal performance of the building significantly. 相似文献
We present the first characterization of a micromachined silicon rectangular waveguide at 400GHz. The silicon waveguide has an average loss of 0.086dB/mm for a range of 350-460GHz. The waveguides are formed using well known microfabrication techniques and demonstrate a successful first step towards the use of silicon waveguides as a viable option for THz systems. 相似文献
The effect of carbon surface oxidation on platinum supported carbon particles (Pt/C) with nitric acid was investigated by
cyclic voltammetry, electrochemical impedance spectroscopy, polarization experiments and chronoamperometry. Cyclic voltammograms,
polarization curves and electrochemical impedance spectra showed that the treated catalyst had much larger active surface
area and higher ionic conductivity than the untreated catalyst, and provided enhanced performance for oxygen reduction. The
formation of acidic groups was examined by IR spectra. The Pt/C surface oxidation had a large effect on the performance of
a gas diffusion electrode for oxygen reduction reaction. 相似文献
A hybrid analytical-intelligent approach is proposed for fuzzy reliability analysis of the composite beams reinforced by zinc oxide (ZnO) nanoparticle. The fuzzy reliability index corresponding to buckling failure mode of nanocomposite beam under thickness-direction external voltage is computed based on three-levels: (1) fuzzy analysis, (2) reliability analysis and (3) analytical buckling analysis. In fuzzy analysis level, an improved gravitational search algorithm has been applied to determine uncertainty interval for membership levels of reliability index. The adaptive formulation with a dynamical self-adjusting process is used for reliability analysis level based on conjugate first-order reliability method (FORM). The self-adjusting term in conjugate sensitivity vector is used to satisfy the sufficient descent condition for controlling instability of FORM formula while the proposed conjugate scalar factor is computed less than the original conjugate FORM, thus it may be provided with the efficient results for the convex problem. The new and previous sensitivity vectors obtained by conjugate and steepest descent vectors dynamically adjusted the proposed conjugate factor. In the buckling analysis level, an exponential theory in conjunction with the method of energy is utilized. Fuzzy random variables including applied voltage, the volume fraction of ZnO, thickness of beam, spring constant and shear constant of the foundation are considered in studied nanocomposite beam. Survey results indicated that the proposed method can provide stable and acceptable fuzzy membership functions for parametric study. Moreover, the ratio of length to thickness and spring constant of foundation are the more sensitive parameters which affect fuzzy reliability index significantly.
Today, air pollution, smoking, use of fatty acids and ready‐made foods, and so on, have exacerbated heart disease. Therefore, controlling the risk of such diseases can prevent or reduce their incidence. The present study aimed at developing an integrated methodology including Markov decision processes (MDP) and genetic algorithm (GA) to control the risk of cardiovascular disease in patients with hypertension and type 1 diabetes. First, the efficiency of GA is evaluated against Grey Wolf optimization (GWO) algorithm, and then, the superiority of GA is revealed. Next, the MDP is employed to estimate the risk of cardiovascular disease. For this purpose, model inputs are first determined using a validated micro‐simulation model for screening cardiovascular disease developed at Tehran University of Medical Sciences, Iran by GA. The model input factors are then defined accordingly and using these inputs, three risk estimation models are identified. The results of these models support WHO guidelines that provide medicine with a high discount to patients with high expected LYs. To develop the MDP methodology, policies should be adopted that work well despite the difference between the risk model and the actual risk. Finally, a sensitivity analysis is conducted to study the behavior of the total medication cost against the changes of parameters. 相似文献