A fully integrated low-IF CMOS GPS radio with on-chip analog image rejection

A fully integrated Global Positioning System (GPS) radio is presented. Low-IF architecture was used for a high level of integration and low power consumption. An on-chip analog image-reject filter provides 18 dB of image-noise rejection to prevent noise figure (NF) degradation. With image rejection performed in the analog radio, a single-path (nonquadrature) output was used. The integrated synthesizer only requires an off-chip phase-locked loop-filter to function. Implemented in a 0.35-/spl mu/m 2P4M CMOS process, the integrated radio has a chip area of 9.5 mm/sup 2/. The radio operates over a wide range of voltage and temperature, from 2.2 to 3.6 V and from -40/spl deg/C to +85/spl deg/C and consumes 27 mW from a 2.2-V supply. The receiver has 4 dB NF.     

Switching contact task control in hydraulic actuators: Stability analysis and experimental evaluation

A switching contact task control for hydraulic actuators is proposed. The controller is built upon three individually designed control laws for three phases of motion: (1) position regulation in free space, (2) impact suppression and stable transition from free to constrained motion and (3) force regulation in sustained‐contact motion. The position and force control schemes are capable of asymptotic set‐point regulation in the presence of actuator friction and without the complexity of sliding mode or adaptive control techniques. The intermediate impact control scheme is included for the first time to dampen the undesirable impacts and dissipate the impact energy that could potentially drive the whole system unstable. The solution concept and the stability of the complete switching control system are analyzed rigorously using the Filippov's solution concept and the concept of Lyapunov exponents. Both computer simulations and experiments are carried out to demonstrate the efficacy of the designed switching control law. Copyright © 2009 John Wiley & Sons, Ltd.     

A new set of sufficient conditions based on coupling parameters for synchronization of Hopfield like Chaotic Neural Networks

In this paper, we consider a Hopfield like Chaotic Neural Networks which have both self-coupling and non-invertible activation functions. We show that the interactions between neurons can be used as a means of chaos generation or suppression to neuron’s outputs when more adaptability or stability is required. Furthermore, a new set of sufficient conditions based on coupling weights is proposed so that the synchronization of all neuron’s outputs with each other is guaranteed, when all neuron’s have identical activation functions. Finally, the effectiveness of the proposed approach is evaluated by performing simulations on three illustrative examples.     

Design and experimental evaluation of a robust force controller for an electro-hydraulic actuator via quantitative feedback theory

This paper presents the design and experimental evaluation of an explicit force controller for a hydraulic actuator in the presence of significant system uncertainties and nonlinearities. The nonlinear version of quantitative feedback theory (QFT) is employed to design a robust time-invariant controller. Two approaches are developed to identify linear time-invariant equivalent model that can precisely represent the nonlinear plant, operating over a wide range. The first approach is based on experimental input–output measurements, obtained directly from the actual system. The second approach is model-based, and utilizes the general nonlinear mathematical model of a hydraulic actuator interacting with an uncertain environment. Given the equivalent models, a controller is then designed to satisfy a priori specified tracking and stability specifications. The controller enjoys the simplicity of fixed-gain controllers while exhibiting robustness. Experimental tests are performed on a hydraulic actuator equipped with a low-cost proportional valve. The results show that the compensated system is not sensitive to the variation of parameters such as environmental stiffness or supply pressure and can equally work well for various set-point forces.     

Stores clustering using a data mining approach for distributing automotive spare-parts to reduce transportation costs

Clustering of retail stores in a distribution network with specific geographical limits plays an important and effective role in distribution and transportation costs reduction. In this paper, the relevant data and information for an established automotive spare-parts distribution and after-sales services company (ISACO) for a 3-year period have been analyzed. With respect to the diversity and lot size of the available information such as stores location, order, goods, transportation vehicles and road and traffic information, three effecting factors with specific weights have been defined for the similarity function: 1. Euclidean distance, 2. Lot size 3. Order concurrency. Based on these three factors, the similarity function has been examined through 5 steps using the Association Rules principles, where the clustering of the stores is performed using k-means algorithm and similar stores are allocated to the clusters. These steps include: 1. Similarity function based on the Euclidean distances, 2. Similarity function based on the order concurrency, 3. Similarity function based on the combination of the order concurrency and lot size, 4. Similarity function based on the combination of these three factors and 5. Improved similarity function. The above mentioned clustering operation for each 5 cases addressed in data mining have been carried out using R software and the improved combinational function has been chosen as the optimal clustering function. Then, trend of each retail store have been analyzed using the improved combinational function and along with determining the priority of the depot center establishment for every cluster, the appropriate distribution policies have been formulated for every cluster. The obtained results of this study indicate a significant cost reduction (32%) in automotive spare-parts distribution and transportation costs.     

Electrohydraulic force control design of a hardware-in-the-loop load emulator using a nonlinear QFT technique

This paper presents the design of a robust force control system for an electrohydraulic load emulator utilized as part of a hardware-in-the-loop flight simulation experiment. In this application, the force controlled hydraulic actuator is used to artificially recreate in-service loads upon a second hydraulic flight actuator operated in closed-loop position control. Electrohydraulic force control is more difficult than electrohydraulic position tracking because the load dynamics influence the force transfer function in a way that makes it challenging to develop an accurate force tracking system using simple feedback control. Nonlinear quantitative feedback theory (QFT) is applied in this paper to address this issue. First, an effective and robust feedback controller is designed by nonlinear QFT to desensitize the force control loop to nonlinear servovalve flow/pressure effects and typical system uncertainties. A secondary compensator is also designed within the QFT framework to extend the force tracking bandwidth with respect to the load motion. Experiments demonstrate acceptable force tracking performance within the scope of a representative flight-simulation experiment.     

Genomics and Epigenomics of Gestational Diabetes Mellitus: Understanding the Molecular Pathways of the Disease Pathogenesis

One of the most common complications during pregnancy is gestational diabetes mellitus (GDM), hyperglycemia that occurs for the first time during pregnancy. The condition is multifactorial, caused by an interaction between genetic, epigenetic, and environmental factors. However, the underlying mechanisms responsible for its pathogenesis remain elusive. Moreover, in contrast to several common metabolic disorders, molecular research in GDM is lagging. It is important to recognize that GDM is still commonly diagnosed during the second trimester of pregnancy using the oral glucose tolerance test (OGGT), at a time when both a fetal and maternal pathophysiology is already present, demonstrating the increased blood glucose levels associated with exacerbated insulin resistance. Therefore, early detection of metabolic changes and associated epigenetic and genetic factors that can lead to an improved prediction of adverse pregnancy outcomes and future cardio-metabolic pathologies in GDM women and their children is imperative. Several genomic and epigenetic approaches have been used to identify the genes, genetic variants, metabolic pathways, and epigenetic modifications involved in GDM to determine its etiology. In this article, we explore these factors as well as how their functional effects may contribute to immediate and future pathologies in women with GDM and their offspring from birth to adulthood. We also discuss how these approaches contribute to the changes in different molecular pathways that contribute to the GDM pathogenesis, with a special focus on the development of insulin resistance.     

Self-esteem stability and depressive symptoms in acute stroke rehabilitation: Methodological and conceptual expansion.

Objectives: Explore the relationship of self-esteem level, self-esteem stability, and other moderating variables with depressive symptoms in acute stroke rehabilitation. Measures: One hundred twenty participants completed measures of state self-esteem, perceived recovery, hospitalization-based hassles, impairment-related distress, and tendency to overgeneralize negative self-connotations of bad events. Self-report of depressive symptoms was collected at admission and on discharge. Four regression analyses explored the relationship of self-esteem level and stability and each of 4 moderating variables (perceived recovery, hassles, impairment-related distress, and overgeneralization) with depressive symptoms at discharge. Results: Analyses indicated significant 3-way interactions in the 4 regression models. In general, individuals with unstable high self-esteem endorsed greater depressive symptoms under conditions of vulnerability (e.g., lower perceived recovery) than did individuals with stable high self-esteem. Under conditions of vulnerability, participants with stable low self-esteem indicated the highest levels of depressive symptoms. Implications: Self-esteem level and stability interact with psychological, environmental, and stroke-specific variables to predict depressive symptoms at discharge from stroke rehabilitation. This suggests the viability of self-esteem stability in exploring depressive symptoms in this setting and the complexity of emotional adjustment early after stroke. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effect of Castration and hormonal supplementation on cholesterol cholelithiasis in the male hamster

This study examined the effect of castration and dietary hormonal supplementation on cholesterol cholelithiasis in male hamsters. Animals fed a standard lithogenic diet developed cholesterol gallstones (17%) after 6 wk, while castrated hamsters did not form any stones. Addition of a synthetic androgen, methyltestosterone, to the lithogenic diet induced cholelithiasis in castrated animals (50%). The biles of normal and castrated-hormone supplemented hamsters had cholesterol saturation indices of 1.0 and 1.1, respectively, while the bile of the castrated animals remained unsaturated (0.6). The ratio of cholic acid/chenodeoxycholic acid in bile increased after castration, but returned to normal levels following hormonal supplementation. Biliary cholesterol carriers were separated by ultracentrifugation. Animals in the stone-forming groups (normal and castrated-hormone treated) had a significant proportion of their biliary cholesterol in vesicles (44 and 46%, respectively); castrated hamsters had less cholesterol in vesicle form (9%). The molar ratio of cholesterol/phospholipid in vesicles was reduced after castration (0.93 vs. 0.42) and increased by hormonal supplementation (1.89). In conclusion, when compared to normal male hamsters fed a standard lithogenic diet, castration reduced the cholesterol saturation of bile, lowered the vesicular/micellar ratio in bile, and inhibited cholesterol cholelithiasis. Dietary androgen supplementation increased the lithogenicity of bile, resulting in stone formation in castrated animals.     

Rotational and axial flow of pseudoplastic fluids

Mechanics of Time-Dependent Materials - Effects of a controllable axial flow on the stability of rotational flow of pseudoplastic fluids in the gap between concentric cylinders are studied. It is...