Objectives The aim of this study was to compare osseous healing characteristics of titanium implants coated with enamel-derived fluoride-substituted
apatite (EFSA) or dentin-derived fluoride-substituted apatite (DFSA).
Methods Fluoride-substituted apatite was derived from extracted human teeth with calcination method at 850 °C. DFSA and EFSA were
separated and carefully ground with a blade grinder. Twenty-four titanium implants were prepared from a 99.99% pure titanium
bar. EFSA and DFSA powders were sprayed separately on implants. As control group, unsprayed and sandblasted pure titanium
implants were used. Eight adult rams were used in the study. One EFSA coated, 1 DFSA coated and 1 control implants were placed
into right tibia of each rams. The rams were sacrificed after 6 months of healing. Undecalcified sections were prepared according
to Donath’s method and histomorphometric evaluation of implants was made.
Results The mean bone contact percentage of DFSA-coated, EFSA-coated and control implants was 89.88% ± 2.34, 70.19% ± 13.11 and 53.12% ± 5.76
respectively. This study suggests that DFSA-coated implants achieved better bone contact than EFSA-coated implants (P < 0.05). Also study groups presented better bone contact than control group (P < 0.05).
Conclusions The results of this study show that although DFSA-coated implants achieved better bone contact, both DFSA and EFSA can be
considered as appropriate coating materials. 相似文献
The persistence of drought events largely determines the severity of socioeconomic and ecological impacts, unfortunately the performance of current weather forecasting models (WFM) to simulate such events is subject to great uncertainties. This study is investigating time-domain characteristics of drought persistence over Turkey by applying the detrended fluctuation analysis (DFA) method to the Palmer drought severity index (PDSI). The existence of long-range power-law correlation in PDSI fluctuations is demonstrated for time scales ranging from monthly to decadal. Understanding of such statistical patterns in PDSI values can definitely be a step forward in drought predictability. From a climatological point of view, it is found that the areas with high level DFA scaling exponent (generalized Hurst) indicate the areas of higher sensitivity to droughts and associated risks. Furthermore, the characteristics of the persistence of the PDSI in climate zones have also been examined by applying the Holdridge Life Zones (HLZ) classification. HLZ classification over Turkey leads to two climate-zones: cool-temperate and warm-temperate. In addition, when topography is taken in account, montane (cool-temperate) and lower-montane (warm-temperate) climate zones can be treated as two different zones. It has been observed that the predictable index (PI) of the PDSI derived from the DFA Hurst exponent is relatively high in the cool-temperate and montane climate zones compared to others. In fact, very different PI values were also obtained in a few HLZ climate classes within the same climate zone and with same vegetation index (i.e. steppe, dry-forest, warm-forest etc.).
Many separate tasks must be performed to configure, run, and analyze Earth system modeling applications. This work is motivated by the complexities of running a large modeling system on a high performance network and the need to reduce those complexities, particularly for the average user. Scientific workflow systems can be used to simplify these task and their relationships, although how to implement such systems is still an open research area. In this paper, we present a methodology to combine a scientific workflow and modeling framework approach to create a standardized work environment and provide a first example of a self-describing Earth system model. We then show the results of an example workflow that is based on the proposed methodology. The example workflow allows running and analyzing a global circulation model on both a grid computing environment and a cluster system, with meaningful abstractions for the model and computing environment. As can be seen through this example, a layered approach to collecting provenance and metadata information has the added benefit of documenting a run in far greater detail than before. This approach facilitates exploration of runs and leads to possible reproducibility. 相似文献
Composites of calcinated bovine bone-derived hydroxyapatite (BHA), doped with 2.5, 5, and 10 wt.% ZnO were produced by sintering.
Scanning electron microscopy (SEM) and X-ray diffraction analysis together with measurements of density, compressive strength,
and Vickers microhardness were carried out in the sintered samples. The experimental results showed that the best mechanical
properties were achieved in the samples with 5% addition of ZnO. The highest value of compression strength was achieved after
sintering at 1200 °C (72 MPa) and of microhardness at 1300 °C (548 HV). Prolong heat treatment at 1300 °C results in vulnerable
BHA–ZnO composites to over-firing effect. 相似文献
AbstractWound dressings are very useful materials for accelerating the wound healing process. In this study, nanofibrous wound dressings were produced from blending solution of Poly-lactic acid(PLA)/Chitosan(C)/Starch(S)/Zinc oxide(Z) by electrospinning method. Morphology, chemical interaction, mechanical, water uptake and weight loss tests were performed on each samples. Moreover, the biocompatibility of primary dermal fibroblast (ATCC, PCS-201-012) on prepared wound dressings was investigated with MTT assays in vitro, and the samples were found suitable for cell viability and proliferation. These results suggest that produced nanofibrous wound dressings can be promising candidate for wound dressing applications. 相似文献
The anthocyanins present in black carrot were extracted with pressurized water acidified with sulfuric, citric and lactic
acids. Anthocyanin degradation became significant above 100 °C and there was no improvement when extraction pressure was increased
to 100 bar. Therefore, the extraction from black carrot was carried out at temperatures 50, 75 and 100 °C under 50 bar pressure.
The extraction efficiencies in terms of acylated and non-acylated anthocyanins were comparable for all three acids used to
acidify water at 50 °C, while similar results were observed at 75 °C for both citric and lactic acids. Water acidified with
lactic acid showed significantly higher extraction efficiency at 100 °C compared to water acidified with sulfuric and citric
acids. Highest degree of polymerization together with increasing degree of browning was observed within extracts when sulfuric
acid was used. On the other hand, when organic acids were used to acidify water, a higher extraction efficiency of anthocyanins,
accompanied with a relatively low polymerization and browning was observed, with lactic acid giving the best results. 相似文献
Corneal ulcer, which is brought on by a breach in the epithelial barrier, is a dangerous infection of the avascular corneal stroma. New treatment strategies are needed, suppressing the aggressive nature of the disease and including a combination of different drugs. In this study, vancomycin (VAN) and fluconazole (FLU) dual-drug loaded dual-layered polyvinyl alcohol and gelatin (PVA/GEL) nanofibrous patches are produced by electrospinning. Scanning electron microscopy (SEM) images show smooth surfaces are obtained for both pure and drug-loaded nanofibrous patches. The tensile test results report that loading the FLU and VAN separately into the PVA/GEL patches decrease both the tensile strength and elongation at break and it is further reduced when combining two drug-loaded layers in one patch. According to drug release results, the FLU and VAN-loaded nanofibrous patches show a controlled release profile extending up to 96 h. Moreover, PVA/GEL/FLU, PVA/GEL/VAN, and PVA/GEL/FLU/VAN nanofibrous patches display significant antimicrobial activity against Candida albicans and Staphylococcus aureus. SEM, 4'-6diamidynofenyloindol (DAPI) staining, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay show that PVA/FLU and PVA/GEL/FLU/VAN nanofibrous patches have a superior effect on NIH3T3 cell spreading and proliferation. The novelty of this study lays in the development of a potential dual drug rapid treatment for corneal ulcers of aggressive nature. 相似文献